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Immunohistochemical Distribution of Beta-Protein Kinase C in Rat Hippocampus Determined with an Antibody against a Synthetic Peptide Sequence.

机译:用抗合成肽序列抗体测定大鼠海马β-蛋白激酶C的免疫组化分布。

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An antibody directed against a synthetic peptide sequence specific for the Beta-subtype of protein kinase C(PKC)was used to determine the distribution of Beta-PKC in rat hippocampus by immunocytochemistry. PKC was distributed primarily in the stratum oriens and radiatum of the CA1 region. Positive staining cell bodies were only observed after colchicine treatment in pyramidal cells (CA2-CA4) and granule cells of the dentate gyrus. The discrete localization of various subtypes of PKC should provide clues to their functions. Keywords: Beta-protein kinase C; Hippocampus; Immunohistochemistry; Reprints. (KT)

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