Hypertonic/Hyperoncotic Resuscitation from Shock: Reduced Volume Requirement and Lower Intracranial Pressure.

摘要

The completed project accomplished the stated goals: To determine the effects on intracranial pressure (ICP) of resuscitation from hemorrhage using conventional volumes of isotonic (SAL) resuscitation solutions in comparison to small volumes of hypertonic 7.2% saline (HS), hyperoncotic 20% hydroxyethylstarch (HES) or the combination of hypertonic 7.2% saline and 20% hydroxyethylstarch (HES/HS). To determine the effects on cerebral blood flow (CBF) of resuscitation from hemorrhage using conventional volumes of isotonic (SAL) resuscitation solutions in comparison to small volumes of hypertonic 7.2% saline (HS), hyperoncotic 20% hydroxyethylstarch (HES), or the combination of hypertonic 7.2% saline and 20% hydroxyethylstarch (HES/HS). (JES)