Treatment of Syphacia Obvelata in Mice Using Invermectin.

摘要

Syphacia obvelata is a common pinworm parasite of wild and laboratory mice. A high proportion of conventional mouse colonies are affected by this parasite, which has a host range that also includes the Norway rat and the Mongolian gerbil. No gross lesions directly attributable to this infestation have been produced experimentally. However, rectal prolapse, intussusception, enteritis, fecal impaction, liver granulomas and poor weight gain have been observed in heavily infected mice. Since parasitized mice are not desirable as experimental subjects, it is important to keep laboratory rodent colonies parasite free. Reported treatments for rodent pinworms include cesarian rederivation or anthelmintics such as piperazines, metronidazole, mebendazole, trichlorfon, thiabendazole, dichlorvos and invermectin. Keywords: Reprints. (KR)