Characterization of African Human Retroviruses Related to HTLV-III/LAV

摘要

Various epidemiologic patterns of HIV-2 and HIV-1 suggest both different population dynamics but also different origins. In HIV-2 prevalent areas, the virus demonstrates features of long-term endemicity. Incidence rates for HIV-2 are low as compared to that of HIV-1 and may reflect other in vitro characteristics; decreased infectivity and cytopathicity. Clinico-prospective studies have still failed to demonstrate AIDS or related symptoms in HIV-2 positive individuals followed both clinically and immunologically. RA 1; Human retroviruses; AIDS; HIV-1; HIV-2; SIV; West Africa. (kt)