Human Herpesvirus Type 6 and HIV Infection in Africa

摘要

Human herpesvirus type 6 (HHV6) was first isolated from patients withlymphoproliferative disorders in 1986. Two of these patients also tested positive for HIV, and subsequently elevated antibody titers to HHV6 were found in HIV seropositives from the USA and Europe. The two viruses do not appear to share the same cellular receptors; however, they do cause additive cytopathic effect in co-infected cells. These associations suggest that HHV6 may be a cofactor in disease caused by HIV infection.