Effect of Helium and Heliox on Glutamate Decarboxylase Activity.

摘要

Humans and experimental animals exposed to ambient pressures of 2.0 MPa or greater experience a disturbance of neurologic function that is manifest as tremor, myoclonus, nausea, and/or psychomotor changes. The appearance of these neurologic symptoms in response to high pressure has been termed the high pressure nervous syndrome (HPNS). Such nervous system dysfunction has prompted a number of studies describing the effects of elevated hydrostatic or gas pressure on neuronal function at the molecular and cellular levels. A review of this literature has been presented by Wann and MacDonald. Keywords: Glutamate decarboxylase, High pressure, Helium, High pressure nervous syndrome. (JS)