Inactivation of Hepatitis A Virus (HAV) by Chlorine and Iodine in Water

摘要

The inactivation kinetics of hepatitis A virus (HAV), poliovirus 1 (Pl) andechovirus 1 (El) by free chlorine and Army iodine (globaline) were studied in phosphate buffered, halogen demand free-water (PBDFW) and in PBDFW supplemented with 5 NTU of clay turbidity and 10 mg/l humic+fulvic acids. HAV was rapidly inactivated by free chlorine under all conditions tested (1-7 mg/L, 5 and 25 C, pH 4.5, 7.0 and 9.5), with 99.99% reductions in <8 minutes. Pl and El were inactivated more slowly than HAV but by >99.99% under most conditions tested. Iodine at 1 and 2 tablets per quart was effective at pH 9.5, with >99.99% inactivation of all three viruses in <10 minutes. However, at pH 4.5 and 7.0 and S C, iodine inactivation of Pl and El was sometimes slow. Iodine may not inactivate HAV and other enteroviruses effectively under some field conditions.