Proceedings of the Workshop on Convulsions and Related Brain Damage Induced byOrganophosphorus Agents Held in Aberdeen Proving Ground, Maryland on 1-2 February 1990

摘要

The Workshop on Convulsions and Related Brain Damage Induced by OrganophosphorusAgents was held at Edgewood Arsenal on 1-2 February 1990. The objectives of the workshop were to: describe the morphological changes in brain tissue induced by organophosphorus agents; review current developments in the research efforts directed toward delineating the mechanism of brain injury induced by organophosphorus agents; and discuss therapeutic approaches aimed at preventing or ameliorating brain injury caused by organophosphorus agents. Critical issues demanding additional research were identified. This proceedings document will serve as a valuable reference guide for scientists interested in the neuropathology and the mechanisms of convulsions associated with nerve agent intoxication. Keywords: Organophosphorus agents, Convulsions, Brain seizures, Anticonvulsant drugs, Neuropathology, Excitatory amino acids, Cholinergic mechanisms, Symposia, Pharmacology. (JG)