Regioselective Aza-Cope Rearrangement of Alpha-Halogenated and NonhalogenatedImines

摘要

The 3-aza-Cope rearrangement of alpha-halogenated and nonhalogenated ketimines bydeprotonation of the corresponding minimum slats was found to be an especially facile and regions selective process. Deuterium labeling studies supported the proposed mechanism which required the rearrangement to be highly concerted. Keywords: Aza-cope, Sigmatropic rearrangement, Compounds, Stereoselective. (JS)