Investigation of Stress Induced Alterations in Neutrophil Function.

摘要

The studies reported here have examined neutrophil activity and function in (1) human subjects engaged in a week-long Bushmaster exercise, a field operation in which military medical students are involved in a simulation of MASH operations and (2) rats subjected to cold stress over a four hour exposure period. Military medical students engaged in four Bushmaster exercises have been studied twice before and once immediately following the exercise. A final measurement was made approximately two weeks following exercise. The findings representing up to 19 subjects suggest that the exercise was associated with a time related increases in neutrophil respiratory burst capacity as measured in nitroblue tetrazolium reactions of chemoattractant stimulated neutrophils. Measures of neutrophils adherence were variable compared to matched control subjects and failed to reflect an exercise effect.