Effectiveness of the Revaccination of Hamadryas Baboons with Dried Live PlagueVaccine NIIS and Yersinia Pestis Fraction I

摘要

In order to prevent illnesses in plague endemic regions the USSR is using a livevaccine made on the basis of the EV plague microbe strain. Numerous studies have demonstrated that among the mass methods of plague vaccine immunization, the inhalation method has the greatest productivity, simplicity and is highly effective. At the the same time it is known that a single injection of live vaccine, including by inhalation, does not ensure the formation of a lengthy and highly intensive immunity. It is therefore necessary to experimentally develop an effective vaccination system that would guarantee a high level of resistance for a lengthy time in those inoculated.