Development of a Mathematical Description of the Olfactory Bulb, Validated withIntracellular and Voltage-Sensitive Dye Recordings

摘要

The objective of this work is to develop a detailed mathematical description ofthe function of the olfactory epithelium and bulb in the tiger salamander, an animal from which we, and others, have obtained substantial morphological, biochemical, physiological and behavioral information. This project focuses especially on incorporating the information available about the number cells, their connectives, and the single sell and ensemble physiological responses using voltage-sensitive dye fluorescence, into the model.