Surface-Bound Membrane-Mimetic Assemblies: Electrostatic Attributes of IntegralMembrane Proteins

摘要

The objective of this project was to develop a system for investigating stimulus-induced displacements of charges associated with integral membrane proteins. A technology was developed for incorporating membrane receptor proteins into matrices that mimic a natural lipid bilayer but which are bound to the surface of solid electrode materials. The focus of the investigation was on the photoreceptor protein, rhodopsin, as a model for a broad class of membrane receptor proteins.