Effects of Feeding on Muscle Blood Flow During Prolonged Exercise in MiniatureSwine

摘要

Eight exercise trained miniature swine were studied during prolonged treadmillruns under fasting and pre-exercise feeding conditions. Each animal ran at identical external work loads for two exercise bouts. Cardiac outputs and stroke volumes were higher and heart rates lower for fed than fasting runs. Preexercise feeding did not alter oxygen consumption, core temperature, mean arterial pressure and arterial-mixed venous oxygen difference during prolonged exercise; however, mixed venous lactate was lower at the end of exercise compared to fasting conditions. Microsphere measurements of regional blood flow revealed higher total gastrointestinal flow for fed compared to fasting conditions. Combined hindlimb muscle blood flow averaged lower under feeding than fasting run conditions.