Investigations of Hemorrhagic Fever with Renal Syndrome (HFRS) in Yugoslavia.

摘要

Five hundred and forty-four rodents and small mammals were trapped in various regions of Yugoslavia and examined. Antihantaviruses, immunofluorescent (IF) antibodies were detected in the blood samples of 129 animals. Antigens were detected in the lung samples of 139 animals. Sixty-seven animals tested positive for both the presence of antibodies in the sera and antigens in the lungs. Hantaviral antibodies and/or antigens were detected most in the yellow-necked mouse (Apodemus flavicollis) (88/189), the wood mouse (Apodemus sylvaticus (28/146), the striped field mouse (Apodemus agrarius) (10/64), house mouse (Mus musculus) (14/29), and the Norway rat (Rattus norvegicus) (14/21). Five other species of rodents and insectivora were infrequently infected. Hantavirus infection in small mammals, according to age, gender, location and species indicated a disparity from region to region prior to and during the epidemic. RA 1; HFRS; Ecology; Human Disease; BD.