Effect of CO sub 2 Laser on Fibroblast Cultures

摘要

Surgeons, particularly in the field of otolaryngology/head and neck surgery, havebeen developing and refining applications for the carbon dioxide (CO2) laser for the past 10 to 15 years. During this time, many studies of CO2 laser wound healing have appeared, most comparing healing of laser and standard scalpel incisions. These reports consistently described delays in CO2 laser wound healing when compared to healing of scalpel incisions. Several studies involving skin wound tensile strength comparisons between scalpel and laser incisions in rats (6) and pigs (2,5) have shown that healing laser wounds are significantly weaker for several weeks post-incision. In a histologic comparison of laser and scalpel incisions in pigs, Norris and Mullarky (10) noted delayed collagen formation in