Use of Adjuvant Containing Mycobacterial Cell-Wall Skeleton, Monophosphoryl LipidA, and Squalane in Malaria Circumsporozoite Protein Vaccine

摘要

Malaria sporozoite vaccines, like many bio-engineered vaccines, do notconsistently induce high concentrations of circulating antibodies. Aluminum salts, introduced as adjuvants in 1926, continue to be essentially the only ones