Molecular Studies of HTLV-1 in a Newly Recognized High Risk Population (AIDS)

摘要

The report summarizes the first year of contract of the research aimed to definenewly recognized high risk population for HTLV-I infection. To define the extent of HTLV-I infection among groups of Jewish immigrants to Israel with an increased frequency of Adult T-cell Leukemia (ATL). Various serological and molecular screening of methods were used, including ELISA and PCR use for molecular survey by amplification of HTLV-I proviral DNA from preipheral blood mononuclear cells DNA. The overall rate of infection was 12% for Jews arriving from Khurusan-North-Eastern Iran. No positive HTLV-I carriers were found from other parts of Iran, Ethiopia, and other Mid-Eastern countries.