Binding of DNA to Alpha/Beta-Type Small, Acid-Soluble Proteins from Spores ofBacillus or Clostridium Species Prevents Formation of Cytosine Dimers, Cytosine-Thymine Dimers, and Bipyrimidine Photoadducts after UV Irradiation

摘要

Small, acid-soluble proteins (SASP) of the alpha/beta-type from spores ofBacillus and Clostridium species bind to DNA; this binding prevents formation of cyclobutane-type thymine dimers upon UV irradiation, but promotes formation of the spore photoproduct, an adduct between adjacent thymine residues. Alpha/beta-