Chemically Sensitive Microelectrochemical Devices: New Approaches to Sensors

摘要

Described herein are the proof of concept results demonstrating a new approach toelectrochemical sensors based upon chemically sensitive microelectrochemical devices. A typical device consists of at least two individually addressable electrodes. The working electrode is a microelectrode and is derivatized with at least one molecule that has a chemically sensitive formal potential and serves as the indicator, and one molecule that has a chemically insensitive formal potential and serves as a reference. The indicator and reference molecules are confined to the electrodes either by monolayer self assembly techniques or by dissolving in a thin film of solid electrolyte. Detection in these systems is accomplished by measuring either the potential difference associated with current peaks for oxidation (or reduction) of microelectrode confined redox reagents.