Ambient Temperature Effects on Thermoregulation and Endurance inAnticholinesterase-Treated Rats

摘要

In sedentary animals, physostigmine (PH) administration resulted in a decreasedcore temperature that is ambient temperature (Ta) dependent. PH administration in rats exercising on a treadmill 26 deg C, 50% rh, 1 1 m/min, 6' incline) decremented endurance and increased rate of rise of core temperature (heating rate, HR). This study was undertaken to examine the effects of Ta on the endurance and thermoregulatory decrements of PH-treated running rats. Adult male rats (510-530g) were given either 0.2mi saline (C) or 100 ug/kg physostigmine salicylate in 0.2 ml saline via tail vein 15 min prior to the start of running to