Decreases in Invasive Haemophilus influenzae Diseases in U.S. Army Children: 1984-1991

摘要

The annual number of cases of Haemophilus influenzae invasive diseases decreasedfrom a high of 188 in 1986 to 43 in 1991. The incidence in the age group at highest risk for Haemophilus influenzae disease, those 6 to 11 months of age, decreased from 355 per 100,00 in 1986 to 116 per 100,000 in 1991 (p .0001, chi square for trend). The incidence for Haemophilus influenzae meningitis declined from 59/100,000 in 1986 to 6/100,000 in 1991 (p .00001, chi square for trend). Conclusions: The decrease in Haemophilus influenzae invasive diseases closely follows the dates of Haemophilus influenzae type b vaccine licensure for use in progressively younger age groups. Some age groups, however, experienced a decline in disease rates even before being eligible for vaccination.... Haemophilus influenzae, Meningitis, Pneumonia, Cellulitis.