Metabolism of 2,2-Dichloro-1,1,1 Trifluoroethane (HCFC-123) by Human HepaticMicrosomes

摘要

As part of its safety evaluation, the in vitro metabolism of 2,2-dichloro-1,1,l-trifluoroethane (HCFC-123), a replacement candidate for Halon 1211, by human hepatic microsomes, was assessed. Microsomal incubations containing HCFC-123 ranging from 6 to 75% (v/v) in the headspace produced increasing amounts of