Electroporation of Bacteria and Yeast: An Experimental Study of Molecular Transport

摘要

This reseaech involves a basic study of electroporation with an emphasis on molecular transport across cell membranes. We have explored a new mechanism for drug delivery, the use of electroporation to move molecules into, across and out of tissues. Electroporation of human skin may provide the basis for greatly enhanced transdermal drug delivery, and for non-invasive 'sensing' of biochemicals within the body. Another advance is a new general method for rapidly determinmg the clonal growth of individual cells.