Non-Invasive Oxygenation Measurements in Surface and Deep Tissues.

摘要

MEDECD has demonstrated the proposed capabilities of MED-DASI (medical-Digital Array Scanned Interferometer) as an oxygenation sensor for deep tissues. We have obtained higher S/N spectra over a broader spectral range in a shorter integration period through a greater depth of tissue than any reported literature spectra. We have obtained hyperspectral oxygenation measurements. We find that spatial information from deep tissues survives and define methods for its retrieval via its spectral content. Typical MED-DASI parameters, as used in these tests, are: Penetration Depth: over 50 mm at 850 nm (flash lamp); Spectral Coverage: 600-1100 nm Spectral Resolution: over 200; Angular resolution: 1 milliradian (imaging); fiber determined for fiber coupling; S/N: over 1000 per frame for integration under 1 sec. Size: test DASI: 1 inch diameter, 3 inch length, (without detector/interface); Weight: 3 oz. Temperature range: +/- 40 deg C; Computer: 486x66 equivalent; Power: battery capable. These capabilities are realized in rugged, small, low weight and power sensors that are insensitive to ambient conditions such light variability, vibration, temperature variability, etc. Hence, the feasibility of a field-capable sensor to measure oxygenation in deep tissues is demonstrated.