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Clinical Studies of Synthetic Peptide-Containing Pulmonary Surfactant in Patientswith Adult Respiratory Distress Syndrome

机译：成人呼吸窘迫综合征患者合成多肽肺表面活性物质的临床研究

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A peptide-containing pulmonary surfactant has been developed, called KL -Surfactant. Assessment of activity and safety has been performed successfully in preterm subhuman primates and in 47 preterm human infants (IND %4O,287). This synthetic surfactant is now being tested in Adult human RDS.

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作者
Cochrane, C. G.;
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年度 1995
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总页数 4
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Respiratory system; Pulmonary insufficiency; Respiratory diseases; Humans; Peptides; Clinical medicine; Signs and symptoms; Primates; Adults; Infants;

机译：呼吸系统;肺功能不全;呼吸系统疾病;人类;多肽;临床医学;体征和症状;灵长类动物;成人;婴儿;

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专利

1. Surfactant treatment before first breath for respiratory distress syndrome in preterm lambs: comparison of a peptide-containing synthetic lung surfactant with porcine-derived surfactant [J] . Johann M van Zyl, Johan Smith Drug Design, Development and Therapy . 2013,第4期

机译：初呼吸对早产羔羊呼吸窘迫综合征的表面活性剂治疗：含肽的合成肺表面活性剂与猪源性表面活性剂的比较
2. A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome [J] . David G Sweet, Mark A Turner, Zbyněk Straňák, Archives of disease in childhood. Fetal and neonatal edition . 2017,第6期

机译：新型SP-B和SP-C富集的合成表面活性剂（CHF5633）在呼吸窘迫综合征早产婴儿中的首次人体临床研究
3. A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome [J] . Sweet David G., Turner Mark A., Stranak Zbynek, Archives of disease in childhood. Fetal and neonatal edition . 2017,第6期

机译：用呼吸窘迫综合征早产儿
4. Retrospective analysis of Pulmonary Surfactant on Respiratory Distress Syndrome of Late Premature or Full-term Infants Paper Title [C] . Hui Wu, Jing Cui, Dan Dang, International Conference on Information Science and Technology Applications . 2013

机译：肺表面活性剂对晚期过早或全职婴幼儿纸标题呼吸窘迫综合征的回顾性分析
5. Development and testing of a modified clinical definition of the acute respiratory distress syndrome. [D] . Ferguson, Niall Douglas. 2002

机译：开发和测试急性呼吸窘迫综合征的改良临床定义。
6. Surfactant treatment before first breath for respiratory distress syndrome in preterm lambs: comparison of a peptide-containing synthetic lung surfactant with porcine-derived surfactant [O] . Johann M van Zyl, Johan Smith 2013

机译：初呼吸对早产羔羊呼吸窘迫综合征的表面活性剂治疗：含肽的合成肺表面活性剂与猪源性表面活性剂的比较
7. Surfactant treatment before first breath for respiratory distress syndrome in preterm lambs : comparison of a peptide-containing synthetic lung surfactant with porcine-derived surfactant [O] . Van Zyl, Johann M., Smith, Johan 2013

机译：早产羔羊呼吸窘迫综合征首次呼吸前的表面活性剂治疗：含肽合成肺表面活性物质与猪源性表面活性剂的比较

Clinical Studies of Synthetic Peptide-Containing Pulmonary Surfactant in Patientswith Adult Respiratory Distress Syndrome

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