Dose (and Time Dependent) Blockade of Pregnancy in Sprague-Dawley Rats Administered Ammonium Dinitramide in the Drinking Water

摘要

Ammonium dinitramide (ADN) is a class 1.1 explosive oxidizer, which may be used in solid rocket propellant mixtures and explosives. A 90-day general toxicity/reproductive screen performed on this compound at doses of 162, 103, 29, and 0.0 mg ADN kg/day resulted in a treatment-related adverse effect on litter production.