Serotonin and the Scientific Basis of Anti-Emetic Therapy

摘要

Vomiting is perhaps the most complex reflex response which makes extensive use ofthe autonomic and motor systems. Involved in the reflex activity are salivation. spasmodic respiratory movement effected by the antagonistic action of the inspiratory and expiratory musculature, gastrointestinal reactions of a specialised nature and posture characteristics of the head. body and appendages typically adapted to the process of expulsion of the gastric contents. In addition, there are psychological and cardiovascular effects which fit into the total integrated response (l).