International Meeting on Cholinesterase (5th). A Satellite Meeting of theInternational Congress of Biochemistry and Molecular Biology

摘要

The principal role played by acetylcholinesterase in neurotransmission within thecentral and peripheral nervous systems commands the interest of chemists, biochemists, cell biologists, pharmacologists, clinical scientists, neuroscientists, and toxicologists. The field has a very large, multidisciplinary, international following. Recent rapid advances in the understanding of molecular properties and structure of the cholinesterases, in genes encoding the enzymes, and pharmacological properties of cholinesterase inhibitors and reactivators provide an opportunity for an unparalleled account of our knowledge of this rapidly evolving field. These developments have arisen from the molecular cloning and characterization of the cholinesterase genes and the elucidation of the three-dimensional structure of acetylcholinesterase.