天南星提取物及其用于创伤‑愈合作用的用途

摘要

本发明提供天南星的水和醇提取物、从天南星分离的化合物(比如3‑O‑(9,12‑十八碳二烯酰基)‑甘油基‑β‑D‑吡喃半乳糖苷、N‑(β‑D‑呋喃核糖‑1‑基)‑苯丙氨酸、和腺苷)、包含前述成分的药物组合物、以及其用于促进创伤愈合的用途。在一个实施方案中，所述药物组合物为局部剂型，比如乳膏剂、软膏剂、泡沫剂、洗剂、硬膏剂、凝胶剂和乳剂。Provided are water and alcohol extracts of Rhizoma arisaematis, compounds isolated from Rhizoma arisaematis (such as 3-O-(9,12-octadecadienoyl)-glyceryl-beta-D-galactopyranoside, N-(beta-D-ribofuranose-1-yl)-phenylalanine, and adenosine), pharmaceutical compositions comprising the aforementioned ingredients, as well as uses thereof for promoting wound healing. In one embodiment, the pharmaceutical composition is a topical formulation, such as a cream, ointment, foam, lotion, plaster, gel, and emulsion.