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Aging Cell

【机译】：老化细胞

ISSN：-
出版周期：Bimonthly
语言：English

起始发布年份：2002
出版者：Oxford, UK : Blackwell Pub., c2002-
出版地：England

NLM刊名缩写：Aging Cell

数据库引入：PubMed: v1n1,Oct. 2002-, PMC

MeSH词表主题词：Aging/physiology; Cellular Senescence/physiology*

备注：Title from cover. Print issues ceased with v. 12, no. 6 (Dec. 2013). Also issued展开▼

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1.Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome

机译：细胞骨架僵硬调节Hutchinson-Gilford Progeria综合征的细胞衰老和先天免疫应答
- 作者：Xiaodong Mu;Chieh Tseng;William S. Hambright;Polina Matre;Chih‐Yi Lin;Palas Chanda;Wanqun Chen;Jianhua Gu;Sudheer Ravuri;Yan Cui;Ling Zhong;John P. Cooke;Laura J. Niedernhofer;Paul D. Robbins;Johnny Huard
- 期刊名称：《Aging Cell》 | 2020年第8期
- accelerated aging;
- cell nucleus;
- cellular senescence;
- skeletal muscle;
- stem cells;
2.Responsiveness of dentate neurons generated throughout adult life is associated with resilience to cognitive aging

机译：在整个成年生命中产生的牙齿神经元的反应性与认知老龄化的韧性相关
- 作者：Marie‐Françoise Montaron;Vanessa Charrier;Nicolas Blin;Pierre Garcia;Djoher Nora Abrous
- 期刊名称：《Aging Cell》 | 2020年第8期
- adult neurogenesis;
- aging cell;
- hippocampus;
- resilience;
- spatial memory;
- successful aging;
3.The inherited methylome landscape is directly altered with paternal aging and associated with offspring neurodevelopmental disorders

机译：遗传性甲基族景观直接用父老化和后代神经发育障碍相关
- 作者：Michelle M. Denomme;Mary E. Haywood;Jason C. Parks;William B. Schoolcraft;Mandy G. Katz‐Jaffe
- 期刊名称：《Aging Cell》 | 2020年第8期
- advanced paternal age;
- blastocyst;
- DNA methylation;
- epigenetics;
- offspring neurodevelopmental disorders;
- sperm;
4.Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27

机译：rab27α/β后神经元α/β后神经元的寿命调节
- 作者：Wen‐Yu Lien;Yu‐Ting Chen;Yi‐Jhan Li;Jie‐Kai Wu;Kuan‐Lin Huang;Jian‐Rong Lin;Shih‐Ching Lin;Chia‐Chun Hou;Horng‐Dar Wang;Chia‐Lin Wu;Shu‐Yi Huang;Chih‐Chiang Chan
- 期刊名称：《Aging Cell》 | 2020年第8期
- Drosophila;
- lifespan extension;
- mushroom body;
- Rab27;
- S6K;
- TOR;
5.Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline

机译：增加龄哺乳动物种系中的精子RDNA和其他重复元素的甲基化
- 作者：Ramya Potabattula;Federica Zacchini;Grazyna Ewa Ptak;Marcus Dittrich;Tobias Müller;Nady El Hajj;Thomas Hahn;Charis Drummer;Rüdiger Behr;Andrea Lucas‐Hahn;Heiner Niemann;Martin Schorsch;Thomas Haaf
- 期刊名称：《Aging Cell》 | 2020年第8期
- embryo developmental potential;
- epigenetic clock;
- germline aging;
- repetitive DNA elements;
- ribosomal DNA;
- sperm DNA methylation;
6.Aging and sex: Impact on microglia phagocytosis

机译：老化和性别：对微胶质细胞增生的影响
- 作者：Natalia Yanguas‐Casás;Andrea Crespo‐Castrillo;Maria‐Angeles Arevalo;Luis Miguel Garcia‐Segura
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- dysfunction;
- irresponsiveness;
- Microglia;
- neuroinflammation;
- phagocytosis;
- sex differences;
7.Liver osteopontin is required to prevent the progression of age‐related nonalcoholic fatty liver disease

机译：需要肝脏骨桥蛋白以防止与年龄相关的非酒精性脂肪肝病的进展
- 作者：Beatriz Gómez‐Santos;Diego Saenz de Urturi;Maitane Nuñez‐García;Francisco Gonzalez‐Romero;Xabier Buque;Igor Aurrekoetxea;Virginia Gutiérrez de Juan;Maria J. Gonzalez‐Rellan;Carmelo García‐Monzón;Águeda González‐Rodríguez;Lorena Mosteiro;Gaizka Errazti;Patricia Mifsut;Sonia Gaztambide;Luis Castaño;Cesar Martin;Rubén Nogueiras;María L. Martinez‐Chantar;Wing‐Kin Syn;Patricia Aspichueta
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- lipid metabolism;
- nonalcoholic fatty liver disease;
- Osteopontin;
- p53;
- senescence;
8.The SIRT6 activator MDL‐800 improves genomic stability and pluripotency of old murine‐derived iPS cells

机译：SIRT6活化剂MDL-800改善了旧鼠衍生的IPS细胞的基因组稳定性和多能性
- 作者：Yu Chen;Jiayu Chen;Xiaoxiang Sun;Jiayu Yu;Zhen Qian;Li Wu;Xiaojun Xu;Xiaoping Wan;Ying Jiang;Jian Zhang;Shaorong Gao;Zhiyong Mao
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- DNA repair;
- genome integrity;
- MDL‐800;
- pluripotency;
- SIRT6;
9.Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages

机译：通过在巨噬细胞中促进刺痛介导的NLRP3活化来衰老肝脏缺血和再灌注损伤
- 作者：Weizhe Zhong;Zhuqing Rao;Jianhua Rao;Guoyong Han;Ping Wang;Tao Jiang;Xiongxiong Pan;Shun Zhou;Haoming Zhou;Xuehao Wang
- 期刊名称：《Aging Cell》 | 2020年第8期
10.Aging is associated with a decline in Atg9b‐mediated autophagosome formation and appearance of enlarged mitochondria in the heart

机译：老化与ATG9B介导的自噬体形成和心脏扩大线粒体的外观有关
- 作者：Wenjing Liang;Alexandra G. Moyzis;Mark A. Lampert;Rachel Y. Diao;Rita H. Najor;Åsa B. Gustafsson
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- Atg9;
- autophagy;
- heart;
- mitochondria;
- mitophagy;
- Parkin;
11.Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss

机译：老化将线粒体动力学转移到裂变以促进种系干细胞损失
- 作者：Oyundari Amartuvshin;Chi‐Hung Lin;Shao‐Chun Hsu;Shih‐Han Kao;Alvin Chen;Wei‐Chun Tang;Han‐Lin Chou;Dong‐Lin Chang;Yen‐Yang Hsu;Bai‐Shiou Hsiao;Elham Rastegari;Kun‐Yang Lin;Yu‐Ting Wang;Chi‐Kuang Yao;Guang‐Chao Chen;Bi‐Chang Chen;Hwei‐Jan Hsu
- 期刊名称：《Aging Cell》 | 2020年第8期
- BMP;
- Drp1;
- GSC;
- Marf;
- mitochondrial fission;
- mitochondrial fusion;
12.The aged hematopoietic system promotes hippocampal‐dependent cognitive decline

机译：老年造血系统促进海马依赖的认知下降
- 作者：Lucas K. Smith;Evgenia Verovskaya;Gregor Bieri;Alana M. Horowitz;Saskia N. I. von Ungern‐Sternberg;Karin Lin;Peter Seizer;Emmanuelle Passegué;Saul A. Villeda
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- cognition;
- cyclophilin A;
- hematopoietic system;
- hippocampus;
13.RTN4B‐mediated suppression of Sirtuin 2 activity ameliorates β‐amyloid pathology and cognitive impairment in Alzheimers disease mouse model

机译：RTN4B介导的SIRTUIN 2活性的抑制改善了阿尔茨海默病小鼠模型中的β-淀粉样蛋白病理学和认知障碍
- 作者：Yan Wang;Jing‐Qi Yang;Ting-Ting Hong;Yuan‐Hong Sun;Hai‐Li Huang;Feng Chen;Xiong‐Jin Chen;Hui‐Yi Chen;Shan‐Shan Dong;Li‐Li Cui;Tie‐Lin Yang
- 期刊名称：《Aging Cell》 | 2020年第8期
- Alzheimers disease;
14.Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice

机译：生长分化因子15保护人和小鼠中衰老介导的全身炎症反应
- 作者：Ji Sun Moon;Ludger J. E. Goeminne;Jung Tae Kim;Jing Wen Tian;Seok‐Hwan Kim;Ha Thi Nga;Seul Gi Kang;Baeki E. Kang;Jin‐Seok Byun;Young‐Sun Lee;Jae‐Han Jeon;Minho Shong;Johan Auwerx;Dongryeol Ryu;Hyon‐Seung Yi
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- inflammation;
- mitochondria;
- senescence;
- T cell;
15.Vascular dysfunction in aged mice contributes to persistent lung fibrosis

机译：老年小鼠的血管功能障碍有助于持续肺纤维化
- 作者：Nunzia Caporarello;Jeffrey A. Meridew;Aja Aravamudhan;Dakota L. Jones;Susan A. Austin;Tho X. Pham;Andrew J. Haak;Kyoung Moo Choi;Qi Tan;Adil Haresi;Steven K. Huang;Zvonimir S. Katusic;Daniel J. Tschumperlin;Giovanni Ligresti
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- eNOS;
- fibroblast activation;
- lung fibrosis;
- vascular dysfunction;
16.A decade of epigenetic change in aging twins: Genetic and environmental contributions to longitudinal DNA methylation

机译：老化双胞胎的表观遗传变化十年：遗传和环境贡献对纵向DNA甲基化
- 作者：Chandra A. Reynolds;Qihua Tan;Elizabeth Munoz;Juulia Jylhävä;Jacob Hjelmborg;Lene Christiansen;Sara Hägg;Nancy L. Pedersen
- 期刊名称：《Aging Cell》 | 2020年第8期
- aging;
- DNA methylation;
- heritability;
- longitudinal;
17.Targeting RAS‐converting enzyme 1 overcomes senescence and improves progeria‐like phenotypes of ZMPSTE24 deficiency

机译：靶向RAS-转换酶1克服衰老并改善了ZMPSTE24缺乏的普形蛋白酶样表型
- 作者：Haidong Yao;Xue Chen;Muhammad Kashif;Ting Wang;Mohamed X. Ibrahim;Elin Tüksammel;Gwladys Revêchon;Maria Eriksson;Clotilde Wiel;Martin O. Bergo
- 期刊名称：《Aging Cell》 | 2020年第8期
- mouse models;
- prelamin A;
- progeria;
- RCE1;
- ZMPSTE24;
18.Modeling the human aging transcriptome across tissues health status and sex

机译：将人衰老转录组跨组织健康状况和性别建模
- 作者：Maxim N. Shokhirev;Adiv A. Johnson
- 期刊名称：《Aging Cell》 | 2021年第1期
- age prediction;
- aging clock;
- machine learning;
- meta‐analysis;
- random forest;
- transcriptomics;
19.Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease

机译：直接转化的星形胶质细胞保留了供体成纤维细胞的老化特征并阐明了对人体CNS健康和疾病的星形胶质效果
- 作者：Noemi Gatto;Cleide Dos Santos Souza;Allan C. Shaw;Simon M. Bell;Monika A. Myszczynska;Samantha Powers;Kathrin Meyer;Lydia M. Castelli;Evangelia Karyka;Heather Mortiboys;Mimoun Azzouz;Guillaume M. Hautbergue;Nóra M. Márkus;Pamela J. Shaw;Laura Ferraiuolo
- 期刊名称：《Aging Cell》 | 2021年第1期
20.SPATA4 improves aging‐induced metabolic dysfunction through promotion of preadipocyte differentiation and adipose tissue expansion

机译：蜘蛛通过促进前脂肪细胞分化和脂肪组织膨胀来改善衰老诱导的代谢功能障碍
- 作者：Zhongchi Li;Kang Xu;Sen Zhao;Yannan Guo;Huiling Chen;Jianquan Ni;Qingfei Liu;Zhao Wang
- 期刊名称：《Aging Cell》 | 2021年第1期
- adipocyte differentiation;
- aging;
- fat redistribution;
- SPATA4;
21.Mitochondrial DNA in extracellular vesicles declines with age

机译：细胞外囊中的线粒体DNA随着年龄的增长而下降
- 作者：Stephanie Lazo;Nicole Noren Hooten;Jamal Green;Erez Eitan;Nicolle A. Mode;Qing‐Rong Liu;Alan B. Zonderman;Ngozi Ezike;Mark P. Mattson;Paritosh Ghosh;Michele K. Evans
- 期刊名称：《Aging Cell》 | 2021年第1期
- aging;
- biomarker;
- circulating cell‐free mitochondrial DNA;
- exosomes;
- extracellular vesicles;
- intercellular communication;
- microvesicles;
- mitochondrial DNA;
22.Effects of myocardial ischemia/reperfusion injury on plasma metabolomic profile during aging

机译：心肌缺血/再灌注损伤对老化血浆代谢型剖面的影响
- 作者：Claudio de Lucia;Michela Piedepalumbo;Lu Wang;Fausto Carnevale Neto;Daniel Raftery;Erhe Gao;Domenico Praticò;Daniel E. L. Promislow;Walter J. Koch
- 期刊名称：《Aging Cell》 | 2021年第1期
- aging;
- heart disease;
- LC‐MS;
- metabolism;
- metabolomics;
- myocardial ischemia;
23.Interleukin‐6 neutralization ameliorates symptoms in prematurely aged mice

机译：白细胞介素-6中和改善过早老年小鼠的症状
- 作者：Stefano Squarzoni;Elisa Schena;Patrizia Sabatelli;Elisabetta Mattioli;Cristina Capanni;Vittoria Cenni;Maria Rosaria DApice;Davide Andrenacci;Giuseppe Sarli;Valeria Pellegrino;Anna Festa;Fabio Baruffaldi;Gianluca Storci;Massimiliano Bonafè;Catia Barboni;Mara Sanapo;Anna Zaghini;Giovanna Lattanzi
- 期刊名称：《Aging Cell》 | 2021年第1期
- accelerated aging;
- ageing;
- anti‐aging;
- cellular senescence;
- cytokines;
- inflammation;
- laminopathies;
- nuclear lamina;
24.Antiallergic drug desloratadine as a selective antagonist of 5HT

机译：抗血糖药物脱氯碱作为5ht的选择性拮抗剂
- 作者：Jian Lu;Chuzhao Zhang;Jianlu Lv;Xialin Zhu;Xingwu Jiang;Weiqiang Lu;Yin Lu;Zongxiang Tang;Jiaying Wang;Xu Shen
- 期刊名称：《Aging Cell》 | 2021年第1期
- 5HT;
25.Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR‐127 in aged animals

机译：外周炎症前述缺血通过涉及老年动物miR-127的机制损害神经元生存期
- 作者：Sanna Loppi;Paula Korhonen;Maria Bouvy‐Liivrand;Simone Caligola;Tiia A. Turunen;Mikko P. Turunen;Ana Hernandez de Sande;Natalia Kołosowska;Flavia Scoyni;Anna Rosell;Teresa García‐Berrocoso;Sighild Lemarchant;Hiramani Dhungana;Joan Montaner;Jari Koistinaho;Katja M. Kanninen;Minna U. Kaikkonen;Rosalba Giugno;Merja Heinäniemi;Tarja Malm
- 期刊名称：《Aging Cell》 | 2021年第1期
- aging;
- inflammation;
- microRNA;
- proteasome;
- sequencing;
- stroke;
26.Up‐regulation of cofilin‐1 in cell senescence associates with morphological change and p27

机译：细胞衰老辅助诱导症的凝结性与形态变化和P27
- 作者：Cheng‐Han Tsai;Chun‐Yuan Chang;Bing‐Ze Lin;Yu‐Lou Wu;Meng‐Hsiu Wu;Liang‐Tin Lin;Wen‐Chien Huang;Jonathan D. Holz;Tzong‐Jen Sheu;Jhih‐Shian Lee;Richard N. Kitsis;Pei‐Han Tai;Yi‐Jang Lee
- 期刊名称：《Aging Cell》 | 2021年第1期
- cofilin‐1;
- growth arrest;
- morphology;
- p27;
27.Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimers disease

机译：光致调节通过激活ERK / MKP7来抑制JNK3以衰减阿尔茨海默病患者的AMPA受体内吞作用
- 作者：Qi Shen;Lei Liu;Xiaotong Gu;Da Xing
- 期刊名称：《Aging Cell》 | 2021年第1期
- Alzheimers disease;
- AMPA receptor endocytosis;
- JNK3;
- Photobiomodulation therapy;
- synaptic dysfunction;
28.Is exercise a senolytic medicine? A systematic review

机译：运动是一种森林药吗？系统评价
- 作者：Xiang‐Ke Chen;Zhen‐Ni Yi;Gordon Tin‐Chun Wong;Kazi Md. Mahmudul Hasan;Joseph Shiu‐Kwong Kwan;Alvin Chun‐Hang Ma;Raymond Chuen‐Chung Chang
- 期刊名称：《Aging Cell》 | 2021年第1期
- cellular senescence;
- exercise;
- senescent cells;
- senolytic medicine;
- senolytics;
29.Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ

机译：衰老通过调节RBPJ的表达促进早期T滤泡辅助细胞分化
- 作者：Louise M. C. Webb;Sigrid Fra‐Bido;Silvia Innocentin;Louise S. Matheson;Noudjoud Attaf;Alexandre Bignon;Julien Novarino;Nicolas Fazilleau;Michelle A. Linterman
- 期刊名称：《Aging Cell》 | 2021年第1期
- age;
- CXCR5;
- Notch;
- RBPJ;
- T follicular helper cells;
30.Diacetyl odor shortens longevity conferred by food deprivation in

机译：二乙酰气味缩短了食物剥夺赋予的寿命
- 作者：Sangsoon Park;Murat Artan;Dae‐Eun Jeong;Hae‐Eun H. Park;Heehwa G. Son;Sieun S. Kim;Yoonji Jung;Yunji Choi;Jin I. Lee;Kyuhyung Kim;Seung‐Jae V. Lee
- 期刊名称：《Aging Cell》 | 2021年第1期
- aging;
31.Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD

机译：Cockayne综合征蛋白CSA和CSB通过NAD维持线粒体稳态
- 作者：Mustafa N. Okur;Evandro F. Fang;Elayne M. Fivenson;Vinod Tiwari;Deborah L. Croteau;Vilhelm A. Bohr
- 期刊名称：《Aging Cell》 | 2020年第12期
- accelerated ageing;
- aging;
- AMPK;
- Cockayne syndrome;
- mitochondrial maintenance;
- mitophagy;
- NAD;
32.On the evolution of cellular senescence

机译：关于细胞衰老的演变
- 作者：Axel Kowald;João F. Passos;Thomas B. L. Kirkwood
- 期刊名称：《Aging Cell》 | 2020年第12期
- aging;
- anti‐aging;
- cellular senescence;
- evolution;
- senolytics;
33.The role of senescent T cells in immunopathology

机译：衰老T细胞在免疫病理学中的作用
- 作者：Luciana P. Covre;Roel P. H. De Maeyer;Daniel C. O. Gomes;Arne N. Akbar
- 期刊名称：《Aging Cell》 | 2020年第12期
- aging;
- senescence;
- T cell;
34.Exercise‐linked improvement in age‐associated loss of balance is associated with increased vestibular input to motor neurons

机译：年龄相关的平衡损失的运动有关的改善与用于运动神经元的前庭输入增加有关
- 作者：Fabienne Battilana;Stefan Steurer;Giorgio Rizzi;Ana C. Delgado;Kelly R. Tan;Christoph Handschin
- 期刊名称：《Aging Cell》 | 2020年第12期
- aging;
- balance;
- exercise;
- motor control;
- motor neurons;
- proprioceptive system;
- training;
- vestibular system;
35.Prevalent intron retention fine‐tunes gene expression and contributes to cellular senescence

机译：普遍的内含子保留细曲面基因表达并有助于细胞衰老
- 作者：Jun Yao;Dong Ding;Xueping Li;Ting Shen;Haihui Fu;Hua Zhong;Gang Wei;Ting Ni
- 期刊名称：《Aging Cell》 | 2020年第12期
- CPNE1;
- intron retention;
- senescence;
- splicing factor;
- U2AF1;
36.Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis

机译：通过平行单细胞分析显示的老年小鼠的卵母细胞的转录组变异和局部DNA甲基化变化增加
- 作者：Juan Castillo‐Fernandez;Erika Herrera‐Puerta;Hannah Demond;Stephen J. Clark;Courtney W. Hanna;Myriam Hemberger;Gavin Kelsey
- 期刊名称：《Aging Cell》 | 2020年第12期
- advanced maternal age;
- chromatin;
- DNA methylation;
- epigenetics;
- gene expression;
- oocytes;
- single‐cell genomics;
37.Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats

机译：花青素通过调节老年大鼠一氧化氮合酶的解压来衰减内皮功能障碍
- 作者：Geum‐Hwa Lee;The‐Hiep Hoang;Eun‐Soo Jung;Su‐Jin Jung;Seong‐Kyu Han;Myoung‐Ja Chung;Soo‐Wan Chae;Han‐Jung Chae
- 期刊名称：《Aging Cell》 | 2020年第12期
- anthocyanins;
- eNOS deacetylation;
- NO;
- senescence;
- SIRT1;
38.Impaired phagocytic function in CX3CR1

机译：CX3CR1中的吞噬功能受损
- 作者：Constance E. Runyan;Lynn C. Welch;Emilia Lecuona;Masahiko Shigemura;Luciano Amarelle;Hiam Abdala‐Valencia;Nikita Joshi;Ziyan Lu;Kiwon Nam;Nikolay S. Markov;Alexandra C. McQuattie‐Pimentel;Raul Piseaux‐Aillon;Yuliya Politanska;Lango Sichizya;Satoshi Watanabe;Kinola J.N. Williams;G. R. Scott Budinger;Jacob I. Sznajder;Alexander V. Misharin
- 期刊名称：《Aging Cell》 | 2020年第9期
- influenza;
- macrophages;
- pneumonia;
- skeletal muscle;
39.FOXO3a acts to suppress DNA double‐strand break‐induced mutations

机译：FOXO3A起抑制DNA双链断裂引起的突变
- 作者：Ryan R. White;Alexander Y. Maslov;Moonsook Lee;Samantha E. Wilner;Matthew Levy;Jan Vijg
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
- bleomycin;
- DNA damage;
- DSB repair;
- FOXO3a;
- mutations;
40.Mechanisms by which autophagy regulates memory capacity in ageing

机译：自噬调节老化内存容量的机制
- 作者：Maria De Risi;Giulia Torromino;Michele Tufano;Stéphanie Moriceau;Annabella Pignataro;Manon Rivagorda;Nicolò Carrano;Silvia Middei;Carmine Settembre;Martine Ammassari‐Teule;Fabrizio Gardoni;Andrea Mele;Franck Oury;Elvira De Leonibus
- 期刊名称：《Aging Cell》 | 2020年第9期
- ageing;
- amyloid fibrils;
- alpha‐synuclein;
- autophagy;
- GluA1;
- mild cognitive impairment;
- Spermidine;
41.Plasma proteomic profile of frailty

机译：浆液的血浆蛋白质组学概况
- 作者：Sanish Sathyan;Emmeline Ayers;Tina Gao;Sofiya Milman;Nir Barzilai;Joe Verghese
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
- cumulative frailty score;
- frailty;
- frailty prediction;
- proteomics;
- SomaScan;
42.CD8

机译：CD8.
- 作者：Manuel Moreno‐Valladares;Leire Moreno‐Cugnon;Tulio Mateo Silva;Juan Pablo Garcés;Ander Saenz‐Antoñanzas;María Álvarez‐Satta;Ander Matheu
- 期刊名称：《Aging Cell》 | 2020年第9期
- Aging;
- CD8;
43.The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism reducing inflammation and oxidative stress in high‐fat diet‐fed obese rats

机译：通过改善脂质代谢降低高脂饮食肥胖大鼠的脂质代谢降低炎症和氧化胁迫植物化学癫痫植物的植物化学癫痫术延长了寿命
- 作者：Hang Yuan;Yuqiao Li;Fan Ling;Yue Guan;Dandan Zhang;Qiushuang Zhu;Jinxiao Liu;Yuqing Wu;Yucun Niu
- 期刊名称：《Aging Cell》 | 2020年第9期
- EGCG;
- free fatty acid;
- high‐fat dietary;
- lifespan;
- proteomics;
- transcriptome;
44.Rapid senescence‐like response after acute injury

机译：急性损伤后的快速衰老响应
- 作者：Xiaogang Chu;Jin Wen;Raghavan Pillai Raju
- 期刊名称：《Aging Cell》 | 2020年第9期
- acute senescence;
- aging;
- cell cycle;
- senescence‐associated secretory phenotype;
45.Glucagon‐like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle

机译：胰高血糖素肽1输注克服了较老人肌肉喂养的合成代谢抗性
- 作者：Haitham Abdulla;Bethan E. Phillips;Daniel J. Wilkinson;Marie Limb;Tereza Jandova;Joseph J. Bass;Debbie Rankin;Jessica Cegielski;Mariwan Sayda;Hannah Crossland;John P. Williams;Kenneth Smith;Iskandar Idris;Philip J. Atherton
- 期刊名称：《Aging Cell》 | 2020年第9期
- glucagon‐like peptide 1;
- microvascular blood flow;
- muscle protein breakdown;
- muscle protein synthesis;
46.Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging

机译：鉴定老化小鼠和猪模型中常见的心脏异构改变和Deriocation途径
- 作者：Víctor Fanjul;Inmaculada Jorge;Emilio Camafeita;Álvaro Macías;Cristina González‐Gómez;Ana Barettino;Beatriz Dorado;María Jesús Andrés‐Manzano;José Rivera‐Torres;Jesús Vázquez;Carlos López‐Otín;Vicente Andrés
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
- cardiometabolic disease;
- HGPS;
- Hutchinson–Gilford progeria syndrome;
- mouse models;
- pathophysiology;
- pig models;
- proteomics;
47.Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development

机译：SIRT1通过减缓抗施用胚胎发育所需的卵母细胞质量的年龄相关的下降巩固了女性生育
- 作者：Juvita D. Iljas;Zhe Wei;Hayden A. Homer
- 期刊名称：《Aging Cell》 | 2020年第9期
- ageing;
- fertility;
- mitochondria;
- oocyte;
- oxidative stress;
- Sirt1;
48.Activation of CXCR7 promotes endothelial repair and reduces the carotid atherosclerotic lesions through inhibition of pyroptosis signaling pathways

机译：CXCR7的激活促进内皮修复并通过抑制糊化酶信号通路来减少颈动脉粥样硬化病变
- 作者：Lisha Qiu;Min Zhang;Sheng Zhang;Yalin Tang;Yanyan Zhang;Congcong Li;Yi Wang;Li Jiang;Jialin C. Zheng
- 期刊名称：《Aging Cell》 | 2020年第9期
- atherosclerosis;
- CXCR7;
- human umbilical vein endothelial cells;
- NLRP3;
- ox‐LDL;
49.Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD

机译：线粒体DNA突变通过NADH / NAD的损伤加剧了女性生殖老化
- 作者：Liang Yang;Xiaobing Lin;Haite Tang;Yuting Fan;Sheng Zeng;Lei Jia;Yukun Li;Yanan Shi;Shujing He;Hao Wang;Zhijuan Hu;Xiao Gong;Xiaoyan Liang;Yi Yang;Xingguo Liu
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
- fertility;
- mitochondria;
- mitochondrial DNA;
- nicotinamide mononucleotide;
50.Body weight and high‐fat diet are associated with epigenetic aging in female members of the BXD murine family

机译：体重和高脂饮食与BXD小鼠家族的女性成员中的表观遗传衰老有关
- 作者：Jose Vladimir Sandoval‐Sierra;Alexandra H. B. Helbing;Evan G. Williams;David G. Ashbrook;Suheeta Roy;Robert W. Williams;Khyobeni Mozhui
- 期刊名称：《Aging Cell》 | 2020年第9期
- age acceleration;
- DNA methylation clock;
- life span;
- longevity;
51.Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice

机译：CDC42活性的抑制延伸了寿命减少了老年女性C57BL / 6小鼠中的循环炎性细胞因子
- 作者：Maria Carolina Florian;Hanna Leins;Michael Gobs;Yang Han;Gina Marka;Karin Soller;Angelika Vollmer;Vadim Sakk;Kalpana J. Nattamai;Ahmad Rayes;Xueheng Zhao;Kenneth Setchell;Medhanie Mulaw;Wolfgang Wagner;Yi Zheng;Hartmut Geiger
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
- Cdc42;
- epigenetic clock;
- inflammaging;
- interferon gamma;
- lifespan;
52.Tau‐induced upregulation of C/EBPβ‐TRPC1‐SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration

机译：TAU诱导的C /EBPβ-TRPC1-SOCE信号传导的上调加剧了TAUOPALES：Alzheimer神经变性的恶性循环
- 作者：Jinwang Ye;Ying Yin;Yaling Yin;Huaqiu Zhang;Huali Wan;Lu Wang;Yue Zuo;Di Gao;Mengzhu Li;Jun Li;Yanchao Liu;Dan Ke;Jian‐Zhi Wang
- 期刊名称：《Aging Cell》 | 2020年第9期
53.Attenuation of epigenetic regulator SMARCA4 and ERK‐ETS signaling suppresses aging‐related dopaminergic degeneration

机译：表观遗传调节器SMARCA4和ERK-ETS信号传导抑制衰老相关的多巴胺能退化
- 作者：Ling Sun;Jie Zhang;Wenfeng Chen;Yun Chen;Xiaohui Zhang;Mingjuan Yang;Min Xiao;Fujun Ma;Yizhou Yao;Meina Ye;Zhenkun Zhang;Kai Chen;Fei Chen;Yujun Ren;Shiwei Ni;Xi Zhang;Zhangming Yan;Zhi‐Rong Sun;Hai‐Meng Zhou;Hongqin Yang;Shusen Xie;M. Emdadul Haque;Kun Huang;Yufeng Yang
- 期刊名称：《Aging Cell》 | 2020年第9期
- aging;
54.Dependence of PINK1 accumulation on mitochondrial redox system

机译：PINK1积累对线粒体氧化还原系统的依赖性
- 作者：Feng Gao;Yan Zhang;Xiaoou Hou;Zhouteng Tao;Haigang Ren;Guanghui Wang
- 期刊名称：《Aging Cell》 | 2020年第9期
- autophagy;
- mitochondrion;
- mitophagy;
- neurodegenerative diseases;
- PINK1;
55.Histone methyltransferase Smyd3 is a new regulator for vascular senescence

机译：组蛋白甲基转移酶SMYD3是血管衰老的新调节剂
- 作者：Di Yang;Gang Wei;Fen Long;Hongbo Nie;Xiaoli Tian;Lefeng Qu;ShuangXi Wang;Peng Li;Yue Qiu;Yang Wang;Wanjin Hong;Ting Ni;Xinhua Liu;Yi Zhun Zhu
- 期刊名称：《Aging Cell》 | 2020年第9期
- angiotensin II;
- endothelial cell;
- p21;
- Smyd3;
- vascular senescence;
56.Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus

机译：中年后代的二甲双胍治疗可缓解微胶质激活和海马自噬增强的认知功能
- 作者：Maheedhar Kodali;Sahithi Attaluri;Leelavathi N. Madhu;Bing Shuai;Raghavendra Upadhya;Jenny Jaimes Gonzalez;Xiaolan Rao;Ashok K. Shetty
- 期刊名称：《Aging Cell》 | 2021年第2期
- activated microglia;
- cognitive function;
- metformin;
- neurogenesis;
- neuroinflammation;
57.Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

机译：百岁脑和后代的蛋白质签名建议百岁老人年龄比其他人慢
- 作者：Paola Sebastiani;Anthony Federico;Melody Morris;Anastasia Gurinovich;Toshiko Tanaka;Kevin B. Chandler;Stacy L. Andersen;Gerald Denis;Catherine E. Costello;Luigi Ferrucci;Lori Jennings;David J. Glass;Stefano Monti;Thomas T. Perls
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- longevity;
- protein;
- senescence;
- SomaLogic;
58.α‐ketoglutarate delays age‐related fertility decline in mammals

机译：α-酮急性延迟哺乳动物的年龄相关的生育率下降
- 作者：Zhenzhen Zhang;Changjiu He;Yu Gao;Lu Zhang;Yukun Song;Tianqi Zhu;Kuanfeng Zhu;Dongying Lv;Jing Wang;Xiuzhi Tian;Teng Ma;Pengyun Ji;Wei Cui;Guoshi Liu
- 期刊名称：《Aging Cell》 | 2021年第2期
- mTOR;
- ovarian aging;
- reproduction;
- telomere;
- α‐KG;
59.Pain modulatory network is influenced by sex and age in a healthy state and during osteoarthritis progression in rats

机译：疼痛调制网络受到健康状态的性和年龄的影响以及大鼠骨关节炎进展的影响
- 作者：Joyce T. Da Silva;Christina Tricou;Youping Zhang;Amir Tofighbakhsh;David A. Seminowicz;Jin Y. Ro
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- brain;
- osteoarthritis;
- pain;
- pain inhibition;
- sex;
60.Novel DNA methylation marker discovery by assumption‐free genome‐wide association analysis of cognitive function in twins

机译：新的DNA甲基化标志物通过孪生的认知功能的无假设基因组 - 宽协会分析发现
- 作者：Afsaneh Mohammadnejad;Mette Soerensen;Jan Baumbach;Jonas Mengel‐From;Weilong Li;Jesper Lund;Shuxia Li;Lene Christiansen;Kaare Christensen;Jacob V. B. Hjelmborg;Qihua Tan
- 期刊名称：《Aging Cell》 | 2021年第2期
- Cognitive function;
- epigenetics;
- generalized correlation coefficient;
- linear regression;
- twins;
61.Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice

机译：全身衰老细胞清除减轻了与小鼠的年龄相关的脑炎和认知障碍
- 作者：Mikolaj Ogrodnik;Shane A. Evans;Edward Fielder;Stella Victorelli;Patrick Kruger;Hanna Salmonowicz;Bettina M. Weigand;Ayush D. Patel;Tamar Pirtskhalava;Christine L. Inman;Kurt O. Johnson;Stephanie L. Dickinson;Azucena Rocha;Marissa J. Schafer;Yi Zhu;David B. Allison;Thomas von Zglinicki;Nathan K. LeBrasseur;Tamar Tchkonia;Nicola Neretti;João F. Passos;James L. Kirkland;Diana Jurk
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- brain;
- cognition;
- memory;
- neurodegeneration;
- SASP;
- senescence;
- senolytic;
- telomeres;
62.Preserving transcriptional stress responses as an anti‐aging strategy

机译：保持转录应力应激作为抗衰老策略
- 作者：Yang Cheng;Andrew Pitoniak;Julia Wang;Dirk Bohmann
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- chromatin;
- drosophila;
- Nrf2;
- oxidative stress;
- transcription;
63.MiR‐103‐3p targets the m

机译：mir-103-3p目标是m
- 作者：Zhongyang Sun;Han Wang;Yuxiang Wang;Guodong Yuan;Xin Yu;Hui Jiang;Qi Wu;Binkui Yang;Zebing Hu;Fei Shi;Xinsheng Cao;Shu Zhang;Ting Guo;Jianning Zhao
- 期刊名称：《Aging Cell》 | 2021年第2期
- METTL14;
- miR‐103‐3p;
- N;
64.Targeting age‐specific changes in CD4

机译：针对CD4的年龄特异性变化
- 作者：Yeqi Nian;Jasper Iske;Ryoichi Maenosono;Koichiro Minami;Timm Heinbokel;Markus Quante;Yang Liu;Haruhito Azuma;Jinrui Yang;Reza Abdi;Hao Zhou;Abdallah Elkhal;Stefan G. Tullius
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- cellular immunology;
- cellular senescence;
- interleukin 2;
- metabolic rate;
- mitochondria;
- respiratory chains;
- T cell;
65.Role of sirtuins in bone biology: Potential implications for novel therapeutic strategies for osteoporosis

机译：SIRTUINS在骨质生物学中的作用：对骨质疏松症新治疗策略的潜在影响
- 作者：Qiangqiang Li;Jack Chun‐yiu Cheng;Qing Jiang;Wayne Yuk‐wai Lee
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- bone remodeling;
- osteoporosis;
- sirtuins;
66.Unlike dietary restriction rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice

机译：与膳食限制不同雷帕霉素未能延长寿命并降低葡萄甾体DNA修复缺陷小鼠的转录应激
- 作者：María B. Birkisdóttir;Dick Jaarsma;Renata M. C. Brandt;Sander Barnhoorn;Nicole van Vliet;Sandra Imholz;Conny T. van Oostrom;Bhawani Nagarajah;Eliana Portilla Fernández;Anton J. M. Roks;Ype Elgersma;Harry van Steeg;José A. Ferreira;Jeroen L. A. Pennings;Jan H. J. Hoeijmakers;Wilbert P. Vermeij;Martijn E. T. Dollé
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- dietary restriction;
- DNA damage repair;
- rapamycin;
- transcription stress;
67.Increasing skeletal muscle carnitine content in older individuals increases whole‐body fat oxidation during moderate‐intensity exercise

机译：增加老年人骨骼肌肉肉碱含量增加了中等强度运动期间的全体脂肪氧化
- 作者：Carolyn Chee;Chris E. Shannon;Aisling Burns;Anna L. Selby;Daniel Wilkinson;Kenneth Smith;Paul L. Greenhaff;Francis B. Stephens
- 期刊名称：《Aging Cell》 | 2021年第2期
- carnitine;
- fat oxidation;
- insulin resistance;
- intramyocellular lipid;
- older adults;
- skeletal muscle;
68.Mtor inhibition by INK128 extends functions of the ovary reconstituted from germline stem cells in aging and premature aging mice

机译：MTOR通过INK128抑制卵巢从老化和过早老化小鼠中从种系干细胞重构的卵巢的功能
- 作者：Dai Heng;Xiaoyan Sheng;Chenglei Tian;Jie Li;Linlin Liu;Mo Gou;Lin Liu
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- Hormone;
- INK128;
- primordial germ cells;
- rapamycin;
- reconstituted ovary;
- stem cell transplantation;
69.Age‐related changes in hippocampal‐dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor

机译：P75神经营养蛋白受体介导的海马依赖突触塑性和记忆的年龄相关变化
- 作者：Lik‐Wei Wong;Yee Song Chong;Wei Lin;Lilian Kisiswa;Eunice Sim;Carlos F. Ibáñez;Sreedharan Sajikumar
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- hippocampus;
- Late‐LTP;
- p75;
70.JUNB‐FBXO21‐ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy

机译：Junb-FBXO21-ERK轴通过抑制自噬促进骨关节炎的软骨变性
- 作者：Zhiming Lin;Jianing Miao;Tao Zhang;Ming He;Ziyuan Wang;Xinyuan Feng;Lunhao Bai
- 期刊名称：《Aging Cell》 | 2021年第2期
- autophagy;
- cartilage degeneration;
- ERK;
- FBXO21;
- JUNB;
- metabolism;
- osteoarthritis;
- rats;
71.Lycorine hydrochloride suppresses stress‐induced premature cellular senescence by stabilizing the genome of human cells

机译：通过稳定人细胞的基因组盐酸盐酸盐植物抑制应激诱导的过早细胞衰老
- 作者：Weina Zhang;Jiaqing Yang;Yu Chen;Renhao Xue;Zhiyong Mao;Wen Lu;Ying Jiang
- 期刊名称：《Aging Cell》 | 2021年第2期
- cellular senescence;
- genome integrity;
- homologous recombination;
- Lycorine hydrochloride;
- nonhomologous end joining;
- SIRT1;
- SIRT6;
72.Incomplete proline catabolism drives premature sperm aging

机译：不完全脯氨酸分解代谢驱动过早的精子老化
- 作者：Chia‐An Yen;Sean P. Curran
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
73.Interleukin‐37 improves T‐cell‐mediated immunity and chimeric antigen receptor T‐cell therapy in aged backgrounds

机译：白细胞介素-37改善T细胞介导的免疫和嵌合抗原受体T细胞疗法在年龄的背景下
- 作者：Jamie A. G. Hamilton;Miyoung Y. Lee;Rae Hunter;Raira S. Ank;Jamie Y. Story;Ganesh Talekar;Talia Sisroe;Dov B. Ballak;Andrew Fedanov;Christopher C. Porter;Elan Z. Eisenmesser;Charles A. Dinarello;Sunil S. Raikar;James DeGregori;Curtis J. Henry
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- CAR T‐cells;
- cytokines;
- inflammation;
- leukemia;
- PD‐1;
- signaling;
- T‐cells;
74.Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis

机译：降低的p53与老年人表皮中的不对称干细胞自我更新的下降相关
- 作者：Alexandra Charruyer;Tracy Weisenberger;Hang Li;Ayman Khalifa;Andrew W. Schroeder;Annika Belzer;Ruby Ghadially
- 期刊名称：《Aging Cell》 | 2021年第2期
- asymmetric division;
- epidermis;
- keratinocyte;
- p53;
- self‐renewal;
- stem cell;
75.Delineating the relationship between immune system aging and myogenesis in muscle repair

机译：划定免疫系统衰老与肌肉修复中肌动生殖物的关系
- 作者：Stephanie W. Tobin;Faisal J. Alibhai;Lukasz Wlodarek;Azadeh Yeganeh;Sean Millar;Jun Wu;Shu‐hong Li;Richard D. Weisel;Ren‐Ke Li
- 期刊名称：《Aging Cell》 | 2021年第2期
- aging;
- bone marrow transplant;
- inflammation;
- myogenesis;
- satellite cells;
76.Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells

机译：免疫细胞细胞衰老和细胞衰老的标志性和检测技术
- 作者：Dingxi Zhou;Mariana Borsa;Anna Katharina Simon
- 期刊名称：《Aging Cell》 | 2021年第2期
- ageing markers;
- immunosenescence;
- methods;
77.Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

机译：二甲双胍抑制慢性肾病诱导的DNA损伤和间充质干细胞的衰老
- 作者：Hyoungnae Kim;Mi Ra Yu;Haekyung Lee;Soon Hyo Kwon;Jin Seok Jeon;Dong Cheol Han;Hyunjin Noh
- 期刊名称：《Aging Cell》 | 2021年第2期
- chronic kidney disease;
- DNA damage;
- mesenchymal stem cells;
- metformin;
- senescence;
78.Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells

机译：抑制寿命调节剂PAPP-A通过抑制间充质基质细胞来调节组织稳定性
- 作者：Mary Mohrin;Justin Liu;Jose Zavala‐Solorio;Sakshi Bhargava;John Maxwell Trumble;Alyssa Brito;Dorothy Hu;Daniel Brooks;Georgios Koukos;Lama Alabdulaaly;Jonathan S. Paw;Kayley Hake;Ganesh Kolumam;Mary L. Bouxsein;Roland Baron;Yuliya Kutskova;Adam Freund
- 期刊名称：《Aging Cell》 | 2021年第3期
- aging;
- bone marrow;
- collagen;
- extracellular matrix;
- hematopoiesis;
- insulin/IGF‐1 signalling;
- mesenchymal stem cells;
79.Senescent cells and the incidence of age‐related diseases

机译：衰老细胞和年龄相关疾病的发病率
- 作者：Itay Katzir;Miri Adler;Omer Karin;Netta Mendelsohn‐Cohen;Avi Mayo;Uri Alon
- 期刊名称：《Aging Cell》 | 2021年第3期
- age‐related disease;
- aging;
- cancer;
- cellular senescence;
- diabetes;
- electronic medical records;
- fibrosis;
- incidence rate;
- idiopathic pulmonary fibrosis;
- mathematical model;
- osteoarthritis;
80.ATF3 drives senescence by reconstructing accessible chromatin profiles

机译：ATF3通过重建可接近的染色质谱来驱动衰老
- 作者：Chao Zhang;Xuebin Zhang;Li Huang;Yiting Guan;Xiaoke Huang;Xiao‐Li Tian;Lijun Zhang;Wei Tao
- 期刊名称：《Aging Cell》 | 2021年第3期
- AP‐1;
- ATF3;
- chromatin accessibility;
- IARs;
- DNA methylation;
- heterochromatin;
- DARs;
- senescence;
81.Early growth response 2 (EGR2) is a novel regulator of the senescence programme

机译：早期生长反应2（EGR2）是衰老计划的新型调节因素
- 作者：Eleanor J. Tyler;Ana Gutierrez del Arroyo;Bethany K. Hughes;Ryan Wallis;James C. Garbe;Martha R. Stampfer;Jim Koh;Robert Lowe;Michael P. Philpott;Cleo L. Bishop
- 期刊名称：《Aging Cell》 | 2021年第3期
- cellular senescence;
- EGR2;
- Ink4a;
- p16;
- replicative lifespan;
- senescence;
- transcription factor;
82.Taurine represses age‐associated gut hyperplasia in

机译：牛磺酸镇压年龄相关的肠道增生
- 作者：Gang Du;Zhiming Liu;Zihua Yu;Zhangpeng Zhuo;Yuedan Zhu;Juanyu Zhou;Yang Li;Haiyang Chen
- 期刊名称：《Aging Cell》 | 2021年第3期
- aging;
- ER stress;
- gut;
- intestinal stem cell;
- JNK signaling;
- taurine;
- unfolded protein response;
83.BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy

机译：钻头年龄：基于转录组的老化时钟接近理论极限的准确性
- 作者：David H. Meyer;Björn Schumacher
- 期刊名称：《Aging Cell》 | 2021年第3期
- aging;
- aging clock;
- biological aging;
- biomarkers;
84.Age‐associated mitochondrial complex I deficiency is linked to increased stem cell proliferation rates in the mouse colon

机译：相关的线粒体复合物I缺乏与小鼠结肠中的干细胞增殖速率增加相关联
- 作者：Craig Stamp;Julia C. Whitehall;Anna L. M. Smith;David Houghton;Carla Bradshaw;Elizabeth A. Stoll;Alasdair P. Blain;Doug M. Turnbull;Laura C. Greaves
- 期刊名称：《Aging Cell》 | 2021年第3期
- aging;
- colon;
- complex I;
- mitochondria;
- stem cells;
85.Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15651 Chinese individuals

机译：综合遗传分析显示了新的人类长寿基因座减少了队列队列的群体群体的疾病风险为15651名中国人
- 作者：Xiaomin Liu;Zijun Song;Yan Li;Yao Yao;Mingyan Fang;Chen Bai;Peng An;Huashuai Chen;Zhihua Chen;Biyao Tang;Juan Shen;Xiaotong Gao;Mingrong Zhang;Pengyu Chen;Tao Zhang;Huijue Jia;Xiao Liu;Yong Hou;Huanming Yang;Jian Wang;Fudi Wang;Xun Xu;Junxia Min;Chao Nie;Yi Zeng
- 期刊名称：《Aging Cell》 | 2021年第3期
- centenarians;
- human genetics;
- life span;
- longevity;
- sex difference;
86.Mutation of

机译：突变
- 作者：Yuan Zhao;Bruce Zhang;Ioan Marcu;Faria Athar;Hongyuan Wang;Evgeniy R. Galimov;Hannah Chapman;David Gems
- 期刊名称：《Aging Cell》 | 2021年第3期
- aging;
87.Ibrutinib modulates Aβ/tau pathology neuroinflammation and cognitive function in mouse models of Alzheimers disease

机译：Ibrutinib调节Aβ/ Tau病理神经炎症和在阿尔茨海默病的小鼠模型中的认知功能
- 作者：Hyun‐ju Lee;Seong Gak Jeon;Jieun Kim;Ri Jin Kang;Seong‐Min Kim;Kyung‐Min Han;HyunHee Park;Ki‐taek Kim;You Me Sung;Hye Yeon Nam;Young Ho Koh;Minseok Song;Kyoungho Suk;Hyang‐Sook Hoe
- 期刊名称：《Aging Cell》 | 2021年第3期
- 5xFAD mice;
- Alzheimers disease;
- amyloid beta;
- ibrutinib;
- neuroinflammation;
- PS19 mice;
- spinogenesis;
- tau;
88.Activation of CREB‐mediated autophagy by thioperamide ameliorates β‐amyloid pathology and cognition in Alzheimer’s disease

机译：硫代酰胺激活CREB介导的自噬改善β-淀粉样蛋白病理学和认知在阿尔茨海默病中
- 作者：Jiangong Wang;Bin Liu;Yong Xu;Meizi Yang;Chaoyun Wang;Mengmeng Song;Jing Liu;Wentao Wang;Jingjing You;Fengjiao Sun;Dan Wang;Dunjiang Liu;Haijing Yan
- 期刊名称：《Aging Cell》 | 2021年第3期
89.Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity

机译：老化脑瘫患者的星形胶质细胞营养不良受损突触可塑性
- 作者：Alexander Popov;Alexey Brazhe;Pavel Denisov;Oksana Sutyagina;Li Li;Natalia Lazareva;Alexei Verkhratsky;Alexey Semyanov
- 期刊名称：《Aging Cell》 | 2021年第3期
- ageing;
- astrocyte;
- astrocytic complexity;
- astrocytic cradle;
- glutamate uptake;
- K;
90.Issue Information

机译：发布信息
- 期刊名称：《Aging Cell》 | 2021年第3期
91.Announcement

机译：公告
- 期刊名称：《Aging Cell》 | 2021年第3期
92.Mossy cell synaptic dysfunction causes memory imprecision via miR128 inhibition of STIM2 in Alzheimers disease mouse model

机译：苔藓细胞突触功能障碍通过MIR128抑制Alzheimer疾病小鼠模型的抑制记忆不精确
- 期刊名称：《Aging Cell》 | 2021年第3期
93.Age‐induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge

机译：诱导年龄诱导的线粒体DNA点突变不足以改变代谢稳态以应对营养挑战
- 作者：Timothy M. Moore;Zhenqi Zhou;Alexander R. Strumwasser;Whitaker Cohn;Amanda J. Lin;Kevin Cory;Kate Whitney;Theodore Ho;Timothy Ho;Joseph L. Lee;Daniel H. Rucker;Austin N. Hoang;Kevin Widjaja;Aaron D. Abrishami;Sarada Charugundla;Linsey Stiles;Julian P. Whitelegge;Lorraine P. Turcotte;Jonathan Wanagat;Andrea L. Hevener
- 期刊名称：《Aging Cell》 | 2020年第11期
- aging;
- insulin resistance;
- metabolism;
- mitochondria;
- mitochondrial DNA;
- obesity;
- POLG;
94.FOXO3 targets are reprogrammed as Huntingtons disease neural cells and striatal neurons face senescence with p16

机译：FOXO3目标被重新编程为亨廷顿的疾病神经细胞和纹状体神经元脸上衰老P16
- 作者：Jessica Voisin;Francesca Farina;Swati Naphade;Morgane Fontaine;Kizito‐Tshitoko Tshilenge;Carlos Galicia Aguirre;Alejandro Lopez‐Ramirez;Julia Dancourt;Aurélie Ginisty;Satish Sasidharan Nair;Kuruwitage Lakshika Madushani;Ningzhe Zhang;François‐Xavier Lejeune;Marc Verny;Judith Campisi;Lisa M. Ellerby;Christian Neri
- 期刊名称：《Aging Cell》 | 2020年第11期
- neurodegenerative disease;
- neuronal differentiation;
- neuronal senescence;
- response mechanisms;
- temporal dynamics;
95.Targeting miR‐124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model

机译：靶向miR-124 /脱乳蛋白信号通过抑制老年脑内出血小鼠模型中的凋亡和脱裂病变来改善神经元细胞死亡
- 作者：Wen‐Dai Bao;Xiao‐Ting Zhou;Lan‐Ting Zhou;Fudi Wang;Xiaoping Yin;Youming Lu;Ling‐Qiang Zhu;Dan Liu
- 期刊名称：《Aging Cell》 | 2020年第11期
- apoptosis;
- ferroptosis;
- Fpn;
- intracerebral hemorrhage;
- iron;
- miR‐124;
96.miR‐195 reduces age‐related blood–brain barrier leakage caused by thrombospondin‐1‐mediated selective autophagy

机译：MiR-195减少了由血压素-1介导的选择性自噬引起的年龄相关的血脑屏障泄漏
- 作者：Chien‐Yuan Chen;Yung‐Mei Chao;Hsiu‐Fen Lin;Chao‐Jung Chen;Cheng‐Sheng Chen;Jenq‐Lin Yang;Julie Y. H. Chan;Suh‐Hang H. Juo
- 期刊名称：《Aging Cell》 | 2020年第11期
- blood–brain barrier;
- miR‐195;
- selective autophagy;
- thrombospondin‐1;
- tight junction;
97.microRNA‐146a controls age‐related bone loss

机译：MicroRNA-146A控制年龄相关的骨质损失
- 作者：Victoria Saferding;Melanie Hofmann;Julia S. Brunner;Birgit Niederreiter;Melanie Timmen;Nathaniel Magilnick;Silvia Hayer;Gerwin Heller;Günter Steiner;Richard Stange;Mark Boldin;Gernot Schabbauer;Moritz Weigl;Matthias Hackl;Johannes Grillari;Josef S. Smolen;Stephan Blüml
- 期刊名称：《Aging Cell》 | 2020年第11期
- aging;
- bone metabolism;
- microRNA;
- osteopetrosis;
- osteoporosis;
98.Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age

机译：来自健康个体的血液细胞外囊调节造血干细胞作为人年龄
- 作者：Isabelle Grenier‐Pleau;Kathrin Tyryshkin;Tri Dung Le;John Rudan;Eric Bonneil;Pierre Thibault;Karen Zeng;Cecilia Lässer;David Mallinson;Dimitrios Lamprou;Jialui Hui;Lynne‐Marie Postovit;Edmond Y. W. Chan;Sheela A. Abraham
- 期刊名称：《Aging Cell》 | 2020年第11期
- aging;
- clonal hematopoiesis;
- exosomes;
- extracellular vesicles;
- hematopoiesis;
- hematopoietic stem cells;
99.Parallels between retinal and brain pathology and response to immunotherapy in old late‐stage Alzheimers disease mouse models

机译：视网膜和大脑病理与旧晚期阿尔茨海默病疾病小鼠模型之间的视网膜和大脑病理学与免疫疗法的反应
- 作者：Jonah Doustar;Altan Rentsendorj;Tania Torbati;Giovanna C. Regis;Dieu‐Trang Fuchs;Julia Sheyn;Nazanin Mirzaei;Stuart L. Graham;Prediman K. Shah;Mitra Mastali;Jennifer E. Van Eyk;Keith L. Black;Vivek K. Gupta;Mehdi Mirzaei;Yosef Koronyo;Maya Koronyo‐Hamaoui
- 期刊名称：《Aging Cell》 | 2020年第11期
- astrocytes reactivation;
- glutamine synthetase;
- myeloid cells;
- neurodegenerative disease;
- ocular proteins;
- retina;
- synaptic preservation;
- vascular amyloidosis;
100.Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

机译：增加的骨髓脂肪发生在雌性小鼠中没有有助于年龄依赖性骨质骨质损失
- 作者：Maria Almeida;Ha‐Neui Kim;Li Han;Daohong Zhou;Jeff Thostenson;Ryan M. Porter;Elena Ambrogini;Stavros C. Manolagas;Robert L. Jilka
- 期刊名称：《Aging Cell》 | 2020年第11期
- aging;
- osteoporosis;
- osteoblasts;
- PPARγ;
- rosiglitazone;
- porosity;