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Current Chemical Genomics and Translational Medicine

【机译】：目前的化学基因组学和转化医学

ISSN：-
出版周期：Annual
语言：English

起始发布年份：2013
出版者：Sharjah, U.A.E : Bentham Open, [2013]-[2018]
出版地：United Arab Emirates

数据库引入：PubMed: v7, 2013-v12, 2018, PMC

MeSH词表主题词：Genomics*; Pharmacoepidemiology*; Translational Medical Research*

备注：Articles added as received to annual volume in progress. Description based on:展开▼

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1.NRF2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent

机译：重金属诱导的NRF2氧化应激取决于细胞类型
- 作者：Steven O Simmons;Chun-Yang Fan;Kim Yeoman;John Wakefield;Ram Ramabhadran
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Nrf2 metals oxidative stress reporter gene cell lines toxicity testing.;
2.A High Throughput Assay for Discovery of Bacterial β-Glucuronidase Inhibitors

机译：发现细菌β-葡萄糖醛酸苷酶抑制剂的高通量分析
- 作者：Syed Ahmad;Mark A Hughes;Kimberly T Lane;Matthew R Redinbo;Li-An Yeh;John E Scott
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- β-glucuronidase CPT-11 screen inhibitor.;
3.Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells

机译：测量THP-1细胞中TNF-α的两种高通量筛选方法
- 作者：Kristin P Leister;Ruili Huang;Bonnie L Goodwin;Andrew Chen;Christopher P Austin;Menghang Xia
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- AlphaLISA technology HTRF technology inhibition of TNF-α production qHTS TNF-α 1536-well plate.;
4.Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS)

机译：高通量筛选人类精子特异性甘油醛3-磷酸脱氢酶（GAPDHS）亚型的方法
- 作者：Jonathan Z Sexton;Polina V Danshina;David R Lamson;Mark Hughes;Alan J House;Li-An Yeh;Deborah A O’Brien;Kevin P Williams
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Glycolysis GAPDHS high throughput screening sperm contraceptive.;
5.An Automated Approach to Efficiently Reformat a Large Collection of Compounds

机译：一种有效地重新格式化大量化合物的自动化方法
- 作者：Jimmy Cui;Sergio C Chai;Anang A Shelat;R. Kiplin Guy;Taosheng Chen
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Automation compound dynamic high throughput screening library reformat.;
6.Suppl 1: Promoting Illiteracy in Epigenetics: An Emerging Therapeutic Strategy

机译：增刊1：促进表观遗传学的文盲：一种新兴的治疗策略
- 作者：Tim J Wigle
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
7.Suppl 1: Drug Discovery Toward Antagonists of Methyl-Lysine Binding Proteins

机译：补充1：针对甲基赖氨酸结合蛋白拮抗剂的药物发现
- 作者：J. Martin Herold;Lindsey A Ingerman;Cen Gao;Stephen V Frye
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Histones chromatin chemical probes reader domains methyl-lysine methyl-arginine post-translational modifications pi-cation interactions drug discovery.;
8.Suppl 1: Chemical Biology of Lysine Demethylases

机译：补充1：赖氨酸脱甲基酶的化学生物学
- 作者：Tom D Heightman
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Epigenetic chromatin histone lysine demethylase inhibitor.;
9.Suppl 1: Targets in Epigenetics: Inhibiting the Methyl Writers of the Histone Code

机译：补充1：表观遗传学的目标：抑制组蛋白密码的甲基化作者
- 作者：Julianne M Yost;Ilia Korboukh;Feng Liu;Cen Gao;Jian Jin
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- PRMT inhibitors PKMT inhibitors HMT inhibitors methyltransferase inhibitors small molecule inhibitors drug discovery Epigenetics.;
10.Suppl 1: Structural Chemistry of Human SET Domain Protein Methyltransferases

机译：补充1：人SET域蛋白甲基转移酶的结构化学
- 作者：Matthieu Schapira
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Methyltransferase SET domain structure PMT histone epigenetics.;
11.Suppl 1: Methods for Activity Analysis of the Proteins that Regulate Histone Methylation

机译：补充1：调节组蛋白甲基化的蛋白质活性分析方法
- 作者：Amy M Quinn;Anton Simeonov
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Epigenetics lysine methyltransferase arginine methyltransferase lysine demethylase reader domain histone methylation enzyme assays protein-protein interactions small molecule inhibitors.;
12.Suppl 1: Quantitative Proteomic Approaches to Studying Histone Modifications

机译：增刊1：定量蛋白质组学方法研究组蛋白修饰
- 作者：Barry M Zee;Nicolas L Young;Benjamin A Garcia
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Histone mass spectrometry proteomic modification epigenetic.;
13.Catalytic Specificity of Human Protein Tyrosine Kinases Revealed by Peptide Substrate Profiling

机译：多肽底物分析揭示了人类蛋白质酪氨酸激酶的催化特异性。
- 作者：Julie Blouin;Philippe Roby;Mathieu Arcand;Lucille Beaudet;Francesco Lipari
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Peptide substrates protein-tyrosine kinases.;
14.A Cell-Based Protein-Protein Interaction Method Using a Permuted Luciferase Reporter

机译：基于细胞的蛋白质-蛋白质相互作用方法使用置换的萤光素酶报道分子
- 作者：Haifeng Eishingdrelo;Jidong Cai;Paul Weissensee;Praveen Sharma;Michael J Tocci;Paul S Wright
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2011年第-1期
- Cell-based assay permuted luciferase protein-protein interactions GPCR NHR RTK cell signaling beta-arrestins.;
15.Development of a Cell-Based High-Throughput Assay to Screen for Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3

机译：基于细胞的高通量检测方法的发展以筛选有机阴离子转运多肽1B1和1B3的抑制剂。
- 作者：Chunshan Gui;Amanda Obaidat;Rathnam Chaguturu;Bruno Hagenbuch
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- OATP1B1 OATP1B3 fluorescein-methotrexate cell based assay high-throughput screening.;
16.HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1

机译：HTS兼容的患者衍生的基于细胞的方法以识别小分子调节剂的1型强直性营养不良中异常剪接。
- 作者：Debra A. O’Leary;Leonardo Vargas;Orzala Sharif;Michael E. Garcia;Yury J. Sigal;Siu-Kei Chow;Christian Schmedt;Jeremy S. Caldwell;Achim Brinker;Ingo H. Engels
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Alternative splicing HTS myotonic dystrophy DM1 cell-based assay.;
17.Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis

机译：共晶体结构揭示的新型色氨酸羟化酶抑制剂的抑制机理及动力学分析
- 作者：Giovanni Cianchetta;Terry Stouch;Wangsheng Yu;Zhi-Cai Shi;Leslie W. Tari;Ronald V. Swanson;Michael J Hunter;Isaac D. Hoffman;Qingyun Liu
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Serotonin structure kinetics gastrointestinal disorder carcinoid monooxygenase.;
18.Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase

机译：c-Met激酶的磷酸化依赖状态的高通量筛选
- 作者：Elham Behshad;Ronald M. Klabe;Alexander Margulis;Mary Becker-Pasha;Mark J. Rupar;Paul Collier;Phillip C. Liu;Gregory F. Hollis;Timothy C. Burn;Richard Wynn
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Kinase phosphorylation high throughput screening HTRF c-Met cancer.;
19.Novel Inhibitors of E. coli RecA ATPase Activity

机译：大肠杆菌RecA ATPase活性的新型抑制剂
- 作者：Jonathan Z Sexton;Tim J Wigle;Qingping He;Mark A Hughes;Ginger R Smith;Scott F Singleton;Alfred L Williams;Li-An Yeh
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Antibiotic resistance ATPase inhibition high throughput screening microbial drug resistance RecA SOS response.;
20.Improved Dual-Luciferase Reporter Assays for Nuclear Receptors

机译：改进的核受体双荧光素酶报告基因测定
- 作者：Aileen Paguio;Pete Stecha;Keith V Wood;Frank Fan
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Nuclear receptor luciferase reporter assays HTS drug discovery cytotoxicity.;
21.Fabry Disease – Current Treatment and New Drug Development

机译：法布里病–当前治疗和新药开发
- 作者：Omid Motabar;Ellen Sidransky;Ehud Goldin;Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Fabry Disease Alpha-Galactosidase Lysosomal Storage Disorders Chaperone Therapy High Throughput Screening Drug Development.;
22.A Grid Algorithm for High Throughput Fitting of Dose-Response Curve Data

机译：剂量响应曲线数据高通量拟合的网格算法
- 作者：Yuhong Wang;Ajit Jadhav;Noel Southal;Ruili Huang;Dac-Trung Nguyen
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Curve fitting Hill equation Grid algorithm Dose-response curve High throughput screening.;
23.High Throughput Screening for Inhibitors of Alpha-Galactosidase

机译：高通量筛选α-半乳糖苷酶抑制剂
- 作者：Omid Motabar;Ke Liu;Noel Southall;Juan J Marugan;Ehud Goldin;Ellen Sidransky;Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Alpha-galactosidase inhibitor Fabry disease drug target high throughput screening.;
24.A Rapid Inexpensive High Throughput Screen Method for Neurite Outgrowth

机译：快速廉价的高通量筛选神经突产物的方法
- 作者：Susan T Yeyeodu;Sam M Witherspoon;Nailya Gilyazova;Gordon C Ibeanu
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Nerve growth factor neurite outgrowth high content screening PC12 NS-1 SU6656.;
25.Luciferase Reporter Assay System for Deciphering GPCR Pathways

机译：萤光素酶报告基因检测系统用于解读GPCR途径
- 作者：Zhijie Cheng;Denise Garvin;Aileen Paguio;Pete Stecha;Keith Wood;Frank Fan
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2010年第-1期
- Luciferase Reporter assays GPCR profile of receptor/G protein coupling.;
26.HTS-Compatible β-Lactamase Transcriptional Reporter Gene Assay for Interrogating the Heat Shock Response Pathway

机译：HTS兼容的β-内酰胺酶转录报告基因基因测定用于询问热休克反应途径
- 作者：Michael K Hancock;Menghang Xia;Elizabeth S Frey;Srilatha Sakamuru;Kun Bi
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
27.A Cell-Based β-Lactamase Reporter Gene Assay for the CREB Signaling Pathway

机译：CREB信号通路的基于细胞的β-内酰胺酶报告基因分析
- 作者：Menghang Xia;Vicky Guo;Ruili Huang;James Inglese;Marshall Nirenberg;Christopher P Austin
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
28.Phenotypic Fingerprinting of Small Molecule Cell Cycle Kinase Inhibitors for Drug Discovery

机译：用于药物发现的小分子细胞周期激酶抑制剂的表型指纹图谱。
- 作者：Jonathan Low;Arunava Chakravartty;Wayne Blosser;Michele Dowless;Christopher Chalfant;Patty Bragger;Louis Stancato
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
29.HTRF: A Technology Tailored for Drug Discovery –A Review of Theoretical Aspects and Recent Applications

机译：HTRF：专为药物发现量身定制的技术–理论方面和最新应用的回顾
- 作者：François Degorce;Amy Card;Sharon Soh;Eric Trinquet;Glenn P Knapik;Bing Xie
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
- HTRF TR-FRET GPCR Kinase Biomarker Bioprocess.;
30.In Vitro Viability and Cytotoxicity Testing and Same-Well Multi-Parametric Combinations for High Throughput Screening

机译：高通量筛选的体外生存力和细胞毒性测试以及同等多参数组合
- 作者：Andrew L. Niles;Richard A. Moravec;Terry L. Riss
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
31.A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase

机译：一种高通量检测方法用于鉴定前列腺酸性磷酸酶的小分子调节剂
- 作者：Rylan S Larsen;Mark J Zylka;John E Scott
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
32.An Agarose-Gel Based Method for Transporting Cell Lines

机译：基于琼脂糖凝胶的细胞系运输方法
- 作者：Lingzhi Yang;Chufang Li;Ling Chen;Zhiyuan Li
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
- Cell transportation cell shipment live cell shipment agarose gel agarose gel based cell preservation cryopreserved cells.;
33.Development of Improved Models for Phosphodiesterase-4 Inhibitors with a Multi-Conformational Structure-Based QSAR Method

机译：基于多构象结构的QSAR方法开发磷酸二酯酶4抑制剂的改进模型
- 作者：Adetokunbo Adekoya;Xialan Dong;Jerry Ebalunode;Weifan Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2009年第-1期
34.Inhibition of Inducible Nitric Oxide Synthase Expression by a Novel Small Molecule Activator of the Unfolded Protein Response

机译：新型的小分子活化剂的未折叠的蛋白质反应的诱导型一氧化氮合酶表达的抑制。
- 作者：Kent T Symons;Mark E Massari;Sara J Dozier;Phan M Nguyen;David Jenkins;Mark Herbert;Timothy C Gahman;Stewart A Noble;Natasha Rozenkrants;Yan Zhang;Tadimeti S Rao;Andrew K Shiau;Christian A Hassig
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
35.Improvements in Live Cell Analysis of G Protein Coupled Receptors using Second Generation BD Calcium Assay Kits

机译：使用第二代BD钙测定试剂盒对G蛋白偶联受体进行活细胞分析的改进
- 作者：Xiao Li;Isabel Llorente;Mike Brasch
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
36.A Novel Bioluminescent Protease Assay Using Engineered Firefly Luciferase

机译：使用工程萤火虫荧光素酶的新型生物发光蛋白酶测定
- 作者：Susan S Wigdal;Jessica L Anderson;Gediminas J Vidugiris;John Shultz;Keith V Wood;Frank Fan
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
37.A New Structure-Based QSAR Method Affords both Descriptive and Predictive Models for Phosphodiesterase-4 Inhibitors

机译：一种新的基于结构的QSAR方法同时满足磷酸二酯酶4抑制剂的描述性模型和预测模型。
- 作者：Xialan Dong;Weifan Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
38.A Homogenous Luminescent Proximity Assay for 14-3-3 Interactions with Both Phosphorylated and Nonphosphorylated Client Peptides

机译：14-3-3与磷酸化和非磷酸化客户肽相互作用的同质发光法
- 作者：Yuhong Du;Fadlo R Khuri;Haian Fu
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
- 14-3-3 AlphaScreen protein-protein interaction HTS.;
39.A Novel Fluorogenic Coumarin Substrate for Monitoring Acid Phosphatase Activity at Low pH Environment

机译：用于监测低pH环境下酸性磷酸酶活性的新型荧光香豆素底物
- 作者：Desuo Yang;Zongxiao Li;Yubo Allan Diwu;Hanzhuo Fu;Jinfang Liao;Chunmei Wei;Zhenjun Diwu
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
40.A High Throughput Serum Paraoxonase Assay for Discovery of Small Molecule Modulators of PON1 Activity

机译：高通量血清对氧磷酶测定发现PON1活性的小分子调节剂。
- 作者：Tiffany L Graves;John E Scott
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
41.Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder

机译：谷氨酸能突触功能障碍和强迫症
- 作者：Jonathan T Ting;Guoping Feng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
- OCD Glutamate Glutamatergic Direct pathway Indirect pathway Striatonigral Striatopallidal CSTC Fronto-subcortical Synapse Neurotransmission Genetics SAPAP3 Riluzole Tourette’s syndrome Trichotillomania Neuropsychiatric disorder SSRI N-acetylcysteine Memantine Orbitofrontal cortex SLC1A1 GRIN2B NMDA receptor D-cycloserine Corticostriatal Cortico-striatal.;
42.Comparative Docking Assessment of Glucokinase Interactions with its Allosteric Activators

机译：葡萄糖激酶与其变构活化剂相互作用的对接比较评估
- 作者：Vandana Kumari;Chenglong Li
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
- Molecular docking Molecular recognition Free energy AutoDock glucokinase GKA Glucokinase activator Allosteric Drug design.;
43.Development of Fluorescence Polarization Assays for the Molecular Chaperone Hsp70 Family Members: Hsp72 and DnaK

机译：分子伴侣Hsp70家族成员：Hsp72和DnaK的荧光偏振测定的发展。
- 作者：Laura Ricci;Kevin P Williams
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
44.EDITORIAL

机译：社论
- 作者：Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
45.The Use of AlphaScreen Technology in HTS: Current Status

机译：HTS中AlphaScreen技术的使用：当前状态
- 作者：Richard M Eglen;Terry Reisine;Philippe Roby;Nathalie Rouleau;Chantal Illy;Roger Bossé;Martina Bielefeld
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
46.Multiplexing Bioluminescent and Fluorescent Reporters to Monitor Live Cells

机译：复用生物发光和荧光记者监测活细胞
- 作者：Michael Haugwitz;Omar Nourzaie;Tatiana Garachtchenko;Lanrong Hu;Suvarna Gandlur;Cathy Olsen;Andrew Farmer;Grigoriy Chaga;Hiroaki Sagawa
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
47.Development of a HTRF® Kinase Assay for Determination of Syk Activity

机译：开发用于确定Syk活性的HTRF®激酶测定法
- 作者：Christopher Harbert;Jeannette Marshall;Sharon Soh;Krista Steger
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
48.Cellular Assays for High-Throughput Screening for Modulators of Trk Receptor Tyrosine Kinases

机译：Trk受体酪氨酸激酶调节剂的高通量筛选的细胞分析
- 作者：Jun Wang;Michael K Hancock;Jeanne M Dudek;Kun Bi
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
49.Homogenous Fluorescent Assays for Characterizing Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK)

机译：表征AMP活化蛋白激酶（AMPK）小分子活化剂的均相荧光测定
- 作者：Laurie J Reichling;Steven M Riddle;Baigen Mei;Rica Bruinsma;Tony A Goossens;Kristin G Huwiler;Mark Maffitt;Alyssa M.G Newport;Xiao-Dong Qian;Carmen Ruttimann-Johnson;Kurt W Vogel
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
50.Fluorescent Cascade and Direct Assays for Characterization of RAF Signaling Pathway Inhibitors

机译：荧光级联反应和RAF信号通路抑制剂的表征的直接测定。
- 作者：Kevin R Kupcho;Rica Bruinsma;Tina M Hallis;David A Lasky;Richard L Somberg;Tammy Turek-Etienne;Kurt W Vogel;Kristin G Huwiler
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
- Cascade assay Direct Assay C-RAF B-RAF B-RAF V599E MEK1 ERK2 FRET TR-FRET.;
51.Cellular Ser/Thr-Kinase Assays Using Generic Peptide Substrates

机译：使用通用肽底物的细胞Ser / Thr激酶测定
- 作者：Deanna G Adams;Yu Wang;Puiying A Mak;Jason Chyba;Orzala Shalizi;Jason Matzen;Paul Anderson;Tim R Smith;Michael Garcia;Genevieve L Welch;Emmanuel J Claret;Michel Fink;Anthony P Orth;Jeremy S Caldwell;Achim Brinker
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
52.The Imaging Probe Development Center and the Production of Molecular Imaging Probes

机译：成像探针开发中心和分子成像探针的生产
- 作者：Gary L Griffiths
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
53.Comparison on Functional Assays for Gq-Coupled GPCRs by Measuring Inositol Monophospate-1 and Intracellular Calcium in 1536-Well Plate Format

机译：通过测量1536孔板形式的肌醇单磷酸酯1和细胞内钙来比较Gq偶联GPCR的功能测定
- 作者：Ke Liu;Steve Titus;Noel Southall;Pingjun Zhu;James Inglese;Christopher P Austin;Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2008年第-1期
54.Healthy Adult LDL-C Bears Reverse Association with Serum IL-17A Levels

机译：健康成人LDL-C与血清IL-17A水平负相关
- 作者：Azam Roohi;Mina Tabrizi;Mehdi Yaseri;Fereshteh Mir Mohammadrezaei;Behrouz Nikbin
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2018年第-1期
- Low-density lipoprotein cholesterol LDL-C IL-17A Atherosclerosis Inflammation;
55.Hepatocellular Carcinoma: Causes Mechanism of Progression and Biomarkers

机译：肝细胞癌：原因进展机制和生物标志物
- 作者：Amit Kumar Singh;Ramesh Kumar;Abhay K. Pandey
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2018年第-1期
- HCC HBV Hepatocarcinogenesis Apoptosis Biomarkers MiRNA;
56.Targeting Wolman Disease and Cholesteryl Ester Storage Disease: Disease Pathogenesis and Therapeutic Development

机译：针对Wolman疾病和胆固醇酯存储疾病：疾病发病机理和治疗发展
- 作者：Francis Aguisanda;Natasha Thorne;Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2017年第-1期
- Wolman disease Cholesteryl ester storage disease Lysosomal storage disease High-throughput screening Induced pluripotent stem cells Cell-based disease model;
57.Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity

机译：人肾近端小管上皮细胞的开发及其在复合毒性评估中的应用
- 作者：Shuaizhang Li;Jinghua Zhao;Ruili Huang;Toni Steiner;Maureen Bourner;Michael Mitchell;David C. Thompson;Bin Zhao;Menghang Xia
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2017年第-1期
- Apoptosis Mitochondrial membrane potential (MMP) Nephrotoxicity SA7K cells Transporters;
58.MiR-9 Promotes Apoptosis Via Suppressing SMC1A Expression in GBM Cell Lines

机译：MiR-9通过抑制GBM细胞系中的SMC1A表达促进细胞凋亡。
- 作者：Yong Zu;Zhichuan Zhu;Min Lin;Dafeng Xu;Yongjun Liang;Yueqian Wang;Zhengdong Qiao;Ting Cao;Dan Yang;Lili Gao;Pengpeng Jin;Peng Zhang;Jianjun Fu;Jing Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2017年第-1期
- GBM miR-9 SMC1A U87 U251 apoptosis;
59.Duodenal-Jejunal Bypass Surgery Reverses Diabetic Phenotype and Reduces Obesity in db/db Mice

机译：十二指肠-空肠旁路手术可逆转糖尿病表型并降低db / db小鼠的肥胖
- 作者：Yongjun Liang;Yueqian Wang;Zhengdong Qiao;Ting Cao;Ying Feng;Lin Zhang;Peng Zhang
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2017年第-1期
- Type 2 Diabetes Mellitus (T2DM) Duodenal-Jejunal Bypass (DJB) db/db mice Fasting Blood Glucose (FBG) Fasting Plasma Insulin;
60.Evidence for Natural Selection in Nucleotide Content Relationships Based on Complete Mitochondrial Genomes: Strong Effect of Guanine Content on Separation between Terrestrial and Aquatic Vertebrates

机译：基于完全线粒体基因组的核苷酸含量关系中自然选择的证据：鸟嘌呤含量对陆生和水生脊椎动物分离的强烈影响
- 作者：Kenji Sorimachi;Teiji Okayasu
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2015年第-1期
61.A Facile Method for Simultaneously Measuring Neuronal Cell Viability and Neurite Outgrowth

机译：同时测量神经元细胞活力和神经突生长的简便方法
- 作者：Michael K. Hancock;Leisha Kopp;Navjot Kaur;Bonnie J. Hanson
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2015年第-1期
- Cell membrane stain fluorescence multiplex assay neural cell viability neurite outgrowth plate reader.;
62.Editorial

机译：社论
- 作者：Zhuyin Li
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2014年第Suppl-1期
63.Identifying Small Molecules which Inhibit Autophagy: a PhenotypicScreen Using Image-Based High-Content Cell Analysis

机译：识别抑制自噬的小分子：表型使用基于图像的高内涵细胞分析的屏幕
- 作者：J.V. Peppard;C. Rugg;M. Smicker;C. Dureuil;B. Ronan;O. Flamand;L. Durand;B. Pasquier
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2014年第Suppl-1期
- HTS phenotypic screening autophagy LC3 inhibitors image-based screening high-content screening.;
64.Establishing a High-content Analysis Method for Tubulin Polymerizationto Evaluate Both the Stabilizing and Destabilizing Activities of Compounds

机译：建立微管蛋白聚合的高含量分析方法评估化合物的稳定和去稳定活性
- 作者：Chi Shing Sum;Debra Nickischer;Ming Lei;Andrea Weston;Litao Zhang;Liang Schweizer
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2014年第Suppl-1期
- High-content analysis microtubule polymerization tubulin stabilizer destabilizer.;
65.Live Multicellular Tumor Spheroid Models For High-Content Imagingand Screening In Cancer Drug Discovery

机译：实时多细胞肿瘤球体模型用于高内涵成像和筛选癌症药物中的发现
- 作者：Brian G. Reid;Taleen Jerjian;Purvi Patel;Qiong Zhou;Byong Hoon Yoo;Peter Kabos;Carol A. Sartorius;Daniel V. LaBarbera
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2014年第Suppl-1期
- Multicellular Tumor Spheroid (MCTS) High-Throughput Screening (HTS) High-Content Screening (HCS) Cancer Stem Cells (CSC) Cytokeratin 5 Systems Biology Luminal Breast Cancer Cancer Drug Discovery.;
66.Identification of Thyroid Hormone Receptor Active Compounds Using aQuantitative High-Throughput Screening Platform

机译：甲状腺激素受体活性化合物的鉴定定量高通量筛选平台
- 作者：Jaime Freitas;Nicole Miller;Brenda J. Mengeling;Menghang Xia;Ruili Huang;Keith Houck;Ivonne M.C.M. Rietjens;J. David Furlow;Albertinka J. Murk
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2014年第-1期
67.Development of RNA Aptamer and its Ligand Binding Assay on Microchip Electrophoresis

机译：RNA适体的开发及其在芯片电泳中的配体结合测定
- 作者：Ken-ichi Ohno;Chikara Nakata;Yoshihiro Sano;Fumiko Nishikawa;Satoshi Nishikawa;Hidetoshi Arakawa
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Aptamer conformational differences fluorescence detection intercalating dyes microchip electrophoresis SELEX.;
68.Suppl 1: HaloTag® Platform: From Proteomics to Cellular Analysis and Animal Imaging

机译：补充1：HaloTag®平台：从蛋白质组学到细胞分析和动物成像
- 作者：Mei Cong
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
69.Suppl 1: The HaloTag: Improving Soluble Expression and Applications in Protein Functional Analysis

机译：补充1：HaloTag：改善可溶性表达及其在蛋白质功能分析中的应用
- 作者：Scott N Peterson;Keehwan Kwon
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- HaloTag protein-protein interactions protein-DNA interactions expression immobilization Type 3 secretion factors E. coli RpoA.;
70.Suppl 1: Galectin-1 and Galectin-3 Mediate Protocadherin-24-Dependent Membrane Localization of β-catenin in Colon Cancer Cell Line HCT116

机译：补充1：Galectin-1和Galectin-3介导结肠癌细胞HCT116中β-catenin的Protocadherin-24依赖性膜定位。
- 作者：Rui Ose;Osamu Oharaa;Takahiro Nagase
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- β-catenin galectin-1 galectin-3 HaloTag HCT116 PCDH24 pull-down assay.;
71.Suppl 1: A Dual Reporter Splicing Assay Using HaloTag-containing Proteins

机译：Suppl 1：使用含HaloTag的蛋白质进行双重报告子剪接测定
- 作者：Koichi Oshima;Takahiro Nagase;Kohsuke Imai;Shigeaki Nonoyama;Megumi Obara;Tomoyuki Mizukami;Hiroyuki Nunoi;Hirokazu Kanegane;Futoshi Kuribayashi;Shin Amemiya;Osamu Ohara
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Chronic granulomatous disease CYBB gene HaloTag fusion protein luciferase reporter assay splicing genetic mutation.;
72.Suppl 1: Utilizing HaloTag Technology to Track the Fate of PCSK9 from Intracellular vs. Extracellular Sources

机译：增刊1：利用HaloTag技术跟踪来自细胞内和细胞外来源的PCSK9的命运
- 作者：Xi Ai;Paul Fischer;Oksana C Palyha;Douglas Wisniewski;Brian Hubbard;Karen Akinsanya;Alison M Strack;Anka G Ehrhardt
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Confocal imaging HaloTag intracellular trafficking LDL receptor PCSK9 protein label protein uptake subcellu-lar localization.;
73.Suppl 1: In Vivo Fluorescent Labeling of Tumor Cells with the HaloTag® Technology

机译：补充1：使用HaloTag®技术对肿瘤细胞进行体内荧光标记
- 作者：Jen-Chieh Tseng;Hélène A Benink;Mark G McDougall;Isabel Chico-Calero;Andrew L Kung
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Fluorescent imaging HaloTag tumor xenograft in vivo labeling.;
74.Suppl 1: Development of a Dehalogenase-Based Protein Fusion Tag Capable of Rapid Selective and Covalent Attachment to Customizable Ligands

机译：Suppl 1：开发基于脱卤酶的蛋白质融合标签该标签能够快速选择性和共价结合到可定制的配体上
- 作者：Lance P Encell;Rachel Friedman Ohana;Kris Zimmerman;Paul Otto;Gediminas Vidugiris;Monika G Wood;Georgyi V Los;Mark G McDougall;Chad Zimprich;Natasha Karassina;Randall D Learish;Robin Hurst;James Hartnett;Sarah Wheeler;Pete Stecha;Jami English;Kate Zhao;Jacqui Mendez;Hélène A Benink;Nancy Murphy;Danette L Daniels;Michael R Slater;Marjeta Urh;Aldis Darzins;Dieter H Klaubert;Robert F Bulleit;Keith V Wood
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
75.Suppl 1: HaloTag a Platform Technology for Protein Analysis

机译：增刊1：HaloTag蛋白质分析的平台技术
- 作者：Marjeta Urh;Martin Rosenberg
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- HaloTag technology protein fusion tags protein interactions protein imaging protein purification.;
76.High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington’s Disease Model

机译：亨廷顿病模型中蛋白质聚集和细胞毒性的高通量多重定量
- 作者：Steven A Titus;Noel Southall;Juan Marugan;Christopher P Austin;Wei Zheng
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Huntington’s disease protein aggregation high-throughput screen polyglutamine expansion multiplex assay.;
77.A Comparison of the Performance and Application Differences Between Manual and Automated Patch-Clamp Techniques

机译：手动和自动膜片钳技术的性能和应用差异的比较
- 作者：Xiao Yajuan;Liang Xin;Li Zhiyuan
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Automated patch clamp technique Ion channels Induced pluripotent stem (iPS) cells Drug discovery Drug safety Patch clamp.;
78.A Homogenous Luminescence Assay Reveals Novel Inhibitors for Giardia Lamblia Carbamate Kinase

机译：均相发光分析揭示了贾第鞭毛虫氨基甲酸酯激酶的新型抑制剂。
- 作者：Catherine Z Chen;Noel Southall;Andrey Galkin;Kap Lim;Juan J Marugan;Liudmila Kulakova;Paul Shinn;Danielle van Leer;Wei Zheng;Osnat Herzberg
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2012年第-1期
- Carbamate kinase Giardia high throughput screening assay development.;
79.A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists

机译：多重荧光钙和NFAT报告基因基因鉴定GPCR激动剂。
- 作者：Heeral Sheth;Colleen Gorey;Nicole Roush;Shelly Smallman;Elizabeth Collantes;Maxine Santoro;Barbara Olson;Laura Fitzgerald;Paul H Lee;Xiqiang John Shen
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2013年第-1期
- FLIPR assay fluorescent calcium assay beta-lactamase reporter gene assay GPCR high throughput screening multiplex assay.;
80.Minireview: Targeting GPCR Activated ERK Pathways for Drug Discovery

机译：Minireview：靶向GPCR激活的ERK途径进行药物发现
- 作者：Haifeng Eishingdrelo;Sathapana Kongsamut
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2013年第-1期
81.A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction

机译：HTS兼容分类的HIV-1 Nef / Hck SH3相互作用抑制剂的生化/生物物理检测法。
- 作者：Sebastian Breuer;Sheryll Espinola;Xavier Morelli;Bruce E Torbett;Stefan T Arold;Ingo H Engels
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2013年第-1期
- HIV HTS label-free technology Nef protein-protein interaction inhibitor resonant waveguide grating SH3 TR-FRET.;
82.High-Content Screening of Human Primary Muscle Satellite Cells for New Therapies for Muscular Atrophy/Dystrophy

机译：高水平筛选人类原代肌肉卫星细胞的肌肉萎缩/营养不良的新疗法
- 作者：Lidia S Nierobisz;Bentley Cheatham;Benjamin M Buehrer;Jonathan Z Sexton
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2013年第-1期
83.A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK)

机译：发现与AMP激活的蛋白激酶（AMPK）绑定的小分子的高通量检测
- 作者：Sarah E Sinnett;Jonathan Z Sexton;Jay E Brenman
- 期刊名称：《Current Chemical Genomics and Translational Medicine》 | 2013年第-1期