首页>美国卫生研究院文献>Briefings in Bioinformatics

Briefings in Bioinformatics

【机译】：生物信息学简报

ISSN：-
出版周期：Quarterly
语言：English

起始发布年份：2000
出版者：London ; Birmingham, AL : H. Stewart Publications, [2000-
出版地：England

数据库引入：

MeSH词表主题词：Computational Biology/methods*; Databases, Factual; Medical Informatics; Molecular Sequence Data; Software

备注：Also available online.展开▼

期刊论文

热门论文

年度选择

更多>>

全选（0）

1.Harmonizing semantic annotations for computational models in biology

机译：协调生物学计算模型的语义注释
- 作者：Maxwell Lewis Neal;Matthias König;David Nickerson;Göksel Mısırlı;Reza Kalbasi;Andreas Dräger;Koray Atalag;Vijayalakshmi Chelliah;Michael T Cooling;Daniel L Cook;Sharon Crook;Miguel de Alba;Samuel H Friedman;Alan Garny;John H Gennari;Padraig Gleeson;Martin Golebiewski;Michael Hucka;Nick Juty;Chris Myers;Brett G Olivier;Herbert M Sauro;Martin Scharm;Jacky L Snoep;Vasundra Touré;Anil Wipat;Olaf Wolkenhauer;Dagmar Waltemath
- 期刊名称：《Briefings in Bioinformatics》
- semantic annotation computational modeling knowledge representation modeling standards data integration;
2.Post genome-wide association analysis: dissecting computational pathwayetwork-based approaches

机译：后全基因组关联分析：剖析计算途径/基于网络的方法
- 作者：Emile R Chimusa;Shareefa Dalvie;Collet Dandara;Ambroise Wonkam;Gaston K Mazandu
- 期刊名称：《Briefings in Bioinformatics》
- genome-wide association post-GWAS subnetwork pathways biological network protein–protein interaction;
3.Community-driven roadmap for integrated disease maps

机译：社区驱动的综合疾病图路线图
- 作者：Marek Ostaszewski;Stephan Gebel;Inna Kuperstein;Alexander Mazein;Andrei Zinovyev;Ugur Dogrusoz;Jan Hasenauer;Ronan M T Fleming;Nicolas Le Novère;Piotr Gawron;Thomas Ligon;Anna Niarakis;David Nickerson;Daniel Weindl;Rudi Balling;Emmanuel Barillot;Charles Auffray;Reinhard Schneider
- 期刊名称：《Briefings in Bioinformatics》
- disease maps molecular biology mathematical modeling knowledge repository biocuration translational medicine pathway representation;
4.Nanopore sequencing technology and tools for genome assembly: computational analysis of the current state bottlenecks and future directions

机译：用于基因组组装的纳米孔测序技术和工具：当前状态瓶颈和未来方向的计算分析
- 作者：Damla Senol Cali;Jeremie S Kim;Saugata Ghose;Can Alkan;Onur Mutlu
- 期刊名称：《Briefings in Bioinformatics》
- nanopore sequencing genome sequencing genome analysis assembly mapping;
5.Comprehensive analysis of Helicobacter pylori infection-associated diseases based on miRNA-mRNA interaction network

机译：基于miRNA-mRNA相互作用网络的幽门螺杆菌感染相关疾病综合分析
- 作者：Jue Yang;Hui Song;Kun Cao;Jialei Song;Jianjiang Zhou
- 期刊名称：《Briefings in Bioinformatics》
- Helicobacter pylori miRNA gastric cancer cardiovascular disease;
6.Open-source chemogenomic data-driven algorithms for predicting drug–target interactions

机译：开源化学基因组数据驱动算法用于预测药物-靶标相互作用
- 作者：Ming Hao;Stephen H Bryant;Yanli Wang
- 期刊名称：《Briefings in Bioinformatics》
- drug–target interaction in silico drug repositioning drug discovery chemogenomic data mean percentile ranking open-source code;
7.Bioinformatics for precision oncology

机译：精准肿瘤学的生物信息学
- 作者：Jochen Singer;Anja Irmisch;Hans-Joachim Ruscheweyh;Franziska Singer;Nora C Toussaint;Mitchell P Levesque;Daniel J Stekhoven;Niko Beerenwinkel
- 期刊名称：《Briefings in Bioinformatics》
- cancer molecular tumor board data analysis pipeline mutation calling clinical decision support;
8.Bioinformatics in the Netherlands: the value of a nationwide community

机译：荷兰的生物信息学：全国性社区的价值
- 作者：Celia W G van Gelder;Rob W W Hooft;Merlijn N van Rijswijk;Linda van den Berg;Ruben G Kok;Marcel Reinders;Barend Mons;Jaap Heringa
- 期刊名称：《Briefings in Bioinformatics》
9.Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches

机译：系统生物信息学：通过基于网络的方法提高计算诊断和治疗的精度
- 作者：Anastasis Oulas;George Minadakis;Margarita Zachariou;Kleitos Sokratous;Marilena M Bourdakou;George M Spyrou
- 期刊名称：《Briefings in Bioinformatics》
- Systems Bioinformatics precision medicine computational diagnostics computational therapeutics network analysis drug repurposing;
10.Translational bioinformatics in mental health: open access data sources and computational biomarker discovery

机译：心理健康中的转化生物信息学：开放获取数据源和计算生物标志物的发现
- 作者：Jessica D Tenenbaum;Krithika Bhuvaneshwar;Jane P Gagliardi;Kate Fultz Hollis;Peilin Jia;Liang Ma;Radhakrishnan Nagarajan;Gopalkumar Rakesh;Vignesh Subbian;Shyam Visweswaran;Zhongming Zhao;Leon Rozenblit
- 期刊名称：《Briefings in Bioinformatics》
- translational bioinformatics mental health open access biomarker discovery;
11.Coloured Petri nets for multilevel multiscale and multidimensional modelling of biological systems

机译：彩色Petri网用于生物系统的多层次多尺度和多维建模
- 作者：Fei Liu;Monika Heiner;David Gilbert
- 期刊名称：《Briefings in Bioinformatics》
- multilevel multiscale and multidimensional modelling coloured Petri nets biological systems;
12.An evaluation of noncoding genome annotation tools through enrichment analysis of 15 genome-wide association studies

机译：通过对15个全基因组关联研究的富集分析评估非编码基因组注释工具
- 作者：Boyang Li;Qiongshi Lu;Hongyu Zhao
- 期刊名称：《Briefings in Bioinformatics》
- noncoding genome annotation genome-wide association study enrichment analysis;
13.Evaluation and comparison of methods for recapitulation of 3D spatial chromatin structures

机译：评估和比较3D空间染色质结构概述的方法
- 作者：Jincheol Park;Shili Lin
- 期刊名称：《Briefings in Bioinformatics》
- 3D structure contact maps dependency data resolution;
14.Translational medicine in the Age of Big Data

机译：大数据时代的转化医学
- 作者：Nicholas P Tatonetti
- 期刊名称：《Briefings in Bioinformatics》
- translational bioinformatics data mining observational analysis translational medicine biomedical informatics Big Data;
15.PHAST PHASTER and PHASTEST: Tools for finding prophage in bacterial genomes

机译：PHASTPHASTER和PHASTEST：在细菌基因组中查找噬菌体的工具
- 作者：David Arndt;Ana Marcu;Yongjie Liang;David S Wishart
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics bacterial genome phage prophage metagenomics;
16.Bioinformatics in the Netherlands: the value of a nationwide community

机译：荷兰的生物信息学：全国性社区的价值
- 作者：Celia W G van Gelder;Rob W W Hooft;Merlijn N van Rijswijk;Linda van den Berg;Ruben G Kok;Marcel Reinders;Barend Mons;Jaap Heringa
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics community bioinformatics training interoperability fair data principles national research infrastructure bioinformatics research;
17.Microbial genome analysis: the COG approach

机译：微生物基因组分析：COG方法
- 作者：Michael Y Galperin;David M Kristensen;Kira S Makarova;Yuri I Wolf;Eugene V Koonin
- 期刊名称：《Briefings in Bioinformatics》
- comparative genomics genome annotation enzyme evolution orthologs paralogs;
18.MAFFT online service: multiple sequence alignment interactive sequence choice and visualization

机译：MAFFT在线服务：多序列比对交互式序列选择和可视化
- 作者：Kazutaka Katoh;John Rozewicki;Kazunori D Yamada
- 期刊名称：《Briefings in Bioinformatics》
- multiple sequence alignment sequence analysis phylogenetic tree;
19.A global perspective on evolving bioinformatics and data science training needs

机译：不断发展的生物信息学和数据科学培训需求的全球视角
- 作者：Teresa K Attwood;Sarah Blackford;Michelle D Brazas;Angela Davies;Maria Victoria Schneider
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics training training survey skills gap computational and statistical competency data science training trainers;
20.Federation in genomics pipelines: techniques and challenges

机译：基因组学管道中的联合：技术和挑战
- 作者：Somali Chaterji;Jinkyu Koo;Ninghui Li;Folker Meyer;Ananth Grama;Saurabh Bagchi
- 期刊名称：《Briefings in Bioinformatics》
- computational genomics cyberinfrastructure federation identity management MG-RAST genomic privacy;
21.A comparative study of rank aggregation methods for partial and top ranked lists in genomic applications

机译：基因组应用中部分和最高排名列表的排名聚合方法的比较研究
- 作者：Xue Li;Xinlei Wang;Guanghua Xiao
- 期刊名称：《Briefings in Bioinformatics》
- coverage rate full list meta-analysis partial list performance evaluation top ranked list;
22.Big data management challenges in health research—a literature review

机译：卫生研究中的大数据管理挑战-文献综述
- 作者：Xiaoming Wang;Carolyn Williams;Zhen Hua Liu;Joe Croghan
- 期刊名称：《Briefings in Bioinformatics》
- big data management system performance data quality machine learning SQL and NoSQL;
23.‘Multi-omic’ data analysis using O-miner

机译：使用O-miner进行多组学数据分析
- 作者：Ajanthah Sangaralingam;Abu Z Dayem Ullah;Jacek Marzec;Emanuela Gadaleta;Ai Nagano;Helen Ross-Adams;Jun Wang;Nicholas R Lemoine;Claude Chelala
- 期刊名称：《Briefings in Bioinformatics》
- multi-omics sequencing data analysis data integration O-miner;
24.VirGenA: a reference-based assembler for variable viral genomes

机译：VirGenA：可变病毒基因组的基于参考的汇编程序
- 作者：Gennady G Fedonin;Yury S Fantin;Alexnader V Favorov;German A Shipulin;Alexey D Neverov
- 期刊名称：《Briefings in Bioinformatics》
- viral genome assembly NGS genotyping mixture separation;
25.OPATs: Omnibus P-value association tests

机译：OPAT：Omnibus P值关联测试
- 作者：Chia-Wei Chen;Hsin-Chou Yang
- 期刊名称：《Briefings in Bioinformatics》
- OPATs P-value combination genetic association genome-wide association study;
26.Network approaches to systems biology analysis of complex disease: integrative methods for multi-omics data

机译：复杂疾病的系统生物学分析的网络方法：多组学数据的集成方法
- 作者：Jingwen Yan;Shannon L Risacher;Li Shen;Andrew J Saykin
- 期刊名称：《Briefings in Bioinformatics》
- integrative omics network approaches systems biology computational methods;
27.Establishing a distributed national research infrastructure providing bioinformatics support to life science researchers in Australia

机译：建立分布式国家研究基础设施为澳大利亚生命科学研究人员提供生物信息学支持
- 作者：Maria Victoria Schneider;Philippa C Griffin;Sonika Tyagi;Madison Flannery;Saravanan Dayalan;Simon Gladman;Nathan Watson-Haigh;Philipp E Bayer;Michael Charleston;Ira Cooke;Rob Cook;Richard J Edwards;David Edwards;Dominique Gorse;Malcolm McConville;David Powell;Marc R Wilkins;Andrew Lonie
- 期刊名称：《Briefings in Bioinformatics》
- EMBL-ABR distributed network bioinformatics infrastructure data-driven analysis bioinformatics service bioinformatics training data-driven science national capability services;
28.Mathematical modeling and computational prediction of cancer drug resistance

机译：癌症耐药性的数学建模和计算预测
- 作者：Xiaoqiang Sun;Bin Hu
- 期刊名称：《Briefings in Bioinformatics》
- cancer drug resistance mechanisms mathematical modeling computational prediction drug combination biomarker;
29.Recent computational developments on CLIP-seq data analysis and microRNAtargeting implications

机译：CLIP-seq数据分析和microRNA的最新计算开发定位含义
- 作者：Silvia Bottini;David Pratella;Valerie Grandjean;Emanuela Repetto;Michele Trabucchi
- 期刊名称：《Briefings in Bioinformatics》
- RNA immunoprecipitation;
- bioinformatics workflow computational guideline large-scale analysis quality management microRNAs human pathologies;
30.Power and sample size calculations for high-throughput sequencing-based experiments

机译：基于高通量测序的实验的功效和样本量计算
- 作者：Chung-I Li;David C Samuels;Ying-Yong Zhao;Yu Shyr;Yan Guo
- 期刊名称：《Briefings in Bioinformatics》
- high-throughput sequencing power sample size;
31.Mutational signatures and mutable motifs in cancer genomes

机译：癌症基因组中的突变特征和可变基序
- 作者：Igor B Rogozin;Youri I Pavlov;Alexander Goncearenco;Subhajyoti De;Artem G Lada;Eugenia Poliakov;Anna R Panchenko;David N Cooper
- 期刊名称：《Briefings in Bioinformatics》
- mutation spectra classification DNA sequence context somatic hypermutation cancer genomics methylation;
32.Bioinformatics in Germany: toward a national-level infrastructure

机译：德国的生物信息学：建立国家级基础设施
- 作者：Andreas Tauch;Arwa Al-Dilaimi
- 期刊名称：《Briefings in Bioinformatics》
- de.NBI distributed network bioinformatics infrastructure big data analysis bioinformatics service bioinformatics training;
33.Bioinformatics tools for the identification of gene clusters that biosynthesize specialized metabolites

机译：用于鉴定生物合成专门代谢物的基因簇的生物信息学工具
- 作者：Arvind K Chavali;Seung Y Rhee
- 期刊名称：《Briefings in Bioinformatics》
- metabolic gene cluster biosynthetic gene cluster specialized metabolism secondary metabolism natural products signature enzyme bacteria fungi plant computational biology;
34.Methodological implementation of mixed linear models in multi-locus genome-wide association studies

机译：多基因组全基因组关联研究中混合线性模型的方法学实施
- 作者：Yang-Jun Wen;Hanwen Zhang;Yuan-Li Ni;Bo Huang;Jin Zhang;Jian-Ying Feng;Shi-Bo Wang;Jim M Dunwell;Yuan-Ming Zhang;Rongling Wu
- 期刊名称：《Briefings in Bioinformatics》
35.How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications

机译：Lisp家族语言的优势如何促进构建复杂而灵活的生物信息学应用程序
- 作者：Bohdan B Khomtchouk;Edmund Weitz;Peter D Karp;Claes Wahlestedt
- 期刊名称：《Briefings in Bioinformatics》
36.Critical evaluation of bioinformatics tools for the prediction of protein crystallization propensity

机译：对预测蛋白质结晶倾向的生物信息学工具的重要评估
- 作者：Huilin Wang;Liubin Feng;Geoffrey I Webb;Lukasz Kurgan;Jiangning Song;Donghai Lin
- 期刊名称：《Briefings in Bioinformatics》
- structural genomics protein crystallization propensity target selection bioinformatics sequence analysis machine learning;
37.A review of connectivity map and computational approaches in pharmacogenomics

机译：药物基因组学中的连接图和计算方法综述
- 作者：Aliyu Musa;Laleh Soltan Ghoraie;Shu-Dong Zhang;Galina Glazko;Olli Yli-Harja;Matthias Dehmer;Benjamin Haibe-Kains;Frank Emmert-Streib
- 期刊名称：《Briefings in Bioinformatics》
38.Strategies for processing and quality control of Illumina genotyping arrays

机译：Illumina基因分型阵列的处理和质量控制策略
- 作者：Shilin Zhao;Wang Jing;David C Samuels;Quanghu Sheng;Yu Shyr;Yan Guo
- 期刊名称：《Briefings in Bioinformatics》
- SNP array genotyping genotyping array quality control cluster;
39.Detection of drug–drug interactions through data mining studies using clinical sources scientific literature and social media

机译：通过使用临床来源科学文献和社交媒体的数据挖掘研究来检测药物相互作用
- 作者：Santiago Vilar;Carol Friedman;George Hripcsak
- 期刊名称：《Briefings in Bioinformatics》
- data mining drug–drug interactions adverse drug effects FAERS electronic health records;
40.Genome-wide characterization of lncRNAs in acute myeloidleukemia

机译：急性髓细胞中lncRNA的全基因组表征白血病
- 作者：Lijun Lei;Siyu Xia;Dan Liu;Xiaoqing Li;Jing Feng;Yaqi Zhu;Jun Hu;Linjian Xia;Lieping Guo;Fei Chen;Hui Cheng;Ke Chen;Hanyang Hu;Xiaohua Chen;Feng Li;Shan Zhong;Nupur Mittal;Guohua Yang;Zhijian Qian;Leng Han;Chunjiang He
- 期刊名称：《Briefings in Bioinformatics》
- lncRNA acute myeloid leukemia;
41.Systematic analyses of drugs and disease indications in RepurposeDB revealpharmacological biological and epidemiological factors influencing drugrepositioning

机译：RepurposeDB中药物和疾病适应症的系统分析显示影响药物的药理生物学和流行病学因素重新定位
- 作者：Khader Shameer;Benjamin S Glicksberg;Rachel Hodos;Kipp W Johnson;Marcus A Badgeley;Ben Readhead;Max S Tomlinson;Timothy O’Connor;Riccardo Miotto;Brian A Kidd;Rong Chen;Avi Ma’ayan;Joel T Dudley
- 期刊名称：《Briefings in Bioinformatics》
- precision medicine drug repositioning translational bioinformatics drug development drug discovery precision pharmacology systems pharmacology;
42.DNA copy number profiling using single-cell sequencing

机译：使用单细胞测序进行DNA拷贝数分析
- 作者：Xuefeng Wang;Hao Chen;Nancy R Zhang
- 期刊名称：《Briefings in Bioinformatics》
- change point detection DNA copy number variation single-cell sequencing tumor heterogeneity;
43.Notions of similarity for systems biology models

机译：系统生物学模型的相似性概念
- 作者：Ron Henkel;Robert Hoehndorf;Tim Kacprowski;Christian Knüpfer;Wolfram Liebermeister;Dagmar Waltemath
- 期刊名称：《Briefings in Bioinformatics》
44.Gene co-expression analysis for functional classification and gene–disease predictions

机译：基因共表达分析用于功能分类和基因疾病预测
- 作者：Sipko van Dam;Urmo Võsa;Adriaan van der Graaf;Lude Franke;João Pedro de Magalhães
- 期刊名称：《Briefings in Bioinformatics》
- transcriptomics functional genomics disease gene prediction next-generation sequencing network analysis;
45.miRDis: a Web tool for endogenous and exogenous microRNA discovery based on deep-sequencing data analysis

机译：miRDis：基于深度测序数据分析的内源性和外源性microRNA发现的Web工具
- 作者：Hanyuan Zhang;Bruno Vieira Resende e Silva;Juan Cui
- 期刊名称：《Briefings in Bioinformatics》
- MicroRNA sequencing endogenous microRNA exogenous microRNA microRNA expression novel microRNA;
46.A review of connectivity map and computational approaches in pharmacogenomics

机译：药物基因组学中的连接图和计算方法综述
- 作者：Aliyu Musa;Laleh Soltan Ghoraie;Shu-Dong Zhang;Galina Glazko;Olli Yli-Harja;Matthias Dehmer;Benjamin Haibe-Kains;Frank Emmert-Streib
- 期刊名称：《Briefings in Bioinformatics》
- pharmacogenomics drug discovery bioinformatics drug repurposing drug repositioning big data;
47.Plant genome and transcriptome annotations: from misconceptions to simple solutions

机译：植物基因组和转录组注释：从误解到简单的解决方案
- 作者：Marie E Bolger;Borjana Arsova;Björn Usadel
- 期刊名称：《Briefings in Bioinformatics》
- plant genome annotation plant ontologies plant gene family databases genome annotation pipelines;
48.Design of RNAs: comparing programs for inverse RNA folding

机译：RNA设计：比较反向RNA折叠程序
- 作者：Alexander Churkin;Matan Drory Retwitzer;Vladimir Reinharz;Yann Ponty;Jérôme Waldispühl;Danny Barash
- 期刊名称：《Briefings in Bioinformatics》
- RNA design inverse RNA folding;
49.How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications

机译：Lisp家族语言的优势如何促进构建复杂而灵活的生物信息学应用程序
- 作者：Bohdan B Khomtchouk;Edmund Weitz;Peter D Karp;Claes Wahlestedt
- 期刊名称：《Briefings in Bioinformatics》
- lisp software engineering bioinformatics computational biology programming languages;
50.MTGIpick allows robust identification of genomic islands from a single genome

机译：MTGIpick可以从单个基因组中可靠地鉴定基因组岛
- 作者：Qi Dai;Chaohui Bao;Yabing Hai;Sheng Ma;Tao Zhou;Cong Wang;Yunfei Wang;Wenwen Huo;Xiaoqing Liu;Yuhua Yao;Zhenyu Xuan;Min Chen;Michael Q Zhang
- 期刊名称：《Briefings in Bioinformatics》
- genomic island detection genomic signature feature selection multiscale statistical test boundary detection;
51.Kinase impact assessment in the landscape of fusion genes that retain kinase domains: a pan-cancer study

机译：保留激酶结构域的融合基因中的激酶影响评估：一项全癌研究
- 作者：Pora Kim;Peilin Jia;Zhongming Zhao
- 期刊名称：《Briefings in Bioinformatics》
- kinase gene fusion kinase domain retention gene fusion network precision medicine;
52.Predictive approaches for drug combination discovery in cancer

机译：在癌症中发现药物组合的预测方法
- 作者：Seyed Ali Madani Tonekaboni;Laleh Soltan Ghoraie;Venkata Satya Kumar Manem;Benjamin Haibe-Kains
- 期刊名称：《Briefings in Bioinformatics》
- drug combination cancer predictive methods pharmacogenomics machine learning drug synergy;
53.Evaluation of computational programs to predict HLA genotypes from genomic sequencing data

机译：评估可从基因组测序数据预测HLA基因型的计算程序
- 作者：Denis C Bauer;Armella Zadoorian;Laurence O W Wilson;Natalie P Thorne
- 期刊名称：《Briefings in Bioinformatics》
- HLA genotyping in silico pathology test NGS clinical genomics;
54.Data-driven approaches used for compound library design hit triage and bioactivity modeling in high-throughput screening

机译：用于高通量筛选的化合物库设计命中分类和生物活性建模的数据驱动方法
- 作者：Shardul Paricharak;Oscar Méndez-Lucio;Aakash Chavan Ravindranath;Andreas Bender;Adriaan P IJzerman;Gerard J P van Westen
- 期刊名称：《Briefings in Bioinformatics》
- phenotypic assays library design screening paradigms;
55.An empirical likelihood ratio test robust to individual heterogeneity for differential expression analysis of RNA-seq

机译：对个体异质性具有鲁棒性的经验似然比检验用于RNA-seq的差异表达分析
- 作者：Maoqi Xu;Liang Chen
- 期刊名称：《Briefings in Bioinformatics》
- cancer transcriptome differential expression analysis empirical likelihood ratio test heterogeneity RNA-seq;
56.Transferring entropy to the realm of GxG interactions

机译：将熵转移到GxG交互领域
- 作者：Paola G Ferrario;Inke R König
- 期刊名称：《Briefings in Bioinformatics》
- information theory entropy genetic interactions estimation;
57.Notions of similarity for systems biology models

机译：系统生物学模型的相似性概念
- 作者：Ron Henkel;Robert Hoehndorf;Tim Kacprowski;Christian Knüpfer;Wolfram Liebermeister;Dagmar Waltemath
- 期刊名称：《Briefings in Bioinformatics》
- systems biology network model model version control information retrieval SBML;
58.A systematic evaluation of normalization methods in quantitative label-free proteomics

机译：无定量蛋白质组学中标准化方法的系统评价
- 作者：Tommi Välikangas;Tomi Suomi;Laura L Elo
- 期刊名称：《Briefings in Bioinformatics》
- proteomics normalization label free bias differential expression logarithmic fold change quantitation intragroup variation reproducibility mass spectrometry;
59.Unraveling chloroplast transcriptomes with ChloroSeq an organelle RNA-Seq bioinformatics pipeline

机译：利用细胞器RNA-Seq生物信息学管道ChloroSeq揭示叶绿体转录组
- 作者：David Roy Smith;Matheus Sanitá Lima
- 期刊名称：《Briefings in Bioinformatics》
- chloroplast transcription organelle transcriptomics plastid RNA RNA editing RNA-Seq;
60.A network medicine approach to build a comprehensive atlas for the prognosis of human cancer

机译：一种网络医学方法以建立全面的人类癌症预后图集
- 作者：Fan Zhang;Chunyan Ren;Kwun Kit Lau;Zihan Zheng;Geming Lu;Zhengzi Yi;Yongzhong Zhao;Fei Su;Shaojun Zhang;Bin Zhang;Eric A. Sobie;Weijia Zhang;Martin J. Walsh
- 期刊名称：《Briefings in Bioinformatics》
- landmark for cancer prognosis multi-dimensional cancer genomic data network medicine system medicine;
61.A protein network descriptor server and its use in studying protein disease metabolic and drug targeted networks

机译：蛋白质网络描述符服务器及其在研究蛋白质疾病代谢和药物靶向网络中的用途
- 作者：Peng Zhang;Lin Tao;Xian Zeng;Chu Qin;Shangying Chen;Feng Zhu;Zerong Li;Yuyang Jiang;Weiping Chen;Yu-Zong Chen
- 期刊名称：《Briefings in Bioinformatics》
- network descriptor network feature biological network web server;
62.Benchmarking computational tools for polymorphic transposable element detection

机译：用于多态易位元素检测的基准计算工具
- 作者：Lavanya Rishishwar;Leonardo Mariño-Ramírez;I King Jordan
- 期刊名称：《Briefings in Bioinformatics》
- transposable elements polymorphic transposable element detection next-generation sequencing human genome;
63.Indel detection from RNA-seq data: tool evaluation and strategies for accurate detection of actionable mutations

机译：从RNA序列数据中进行插入缺失检测：工具评估和准确检测可操作突变的策略
- 作者：Zhifu Sun;Aditya Bhagwate;Naresh Prodduturi;Ping Yang;Jean-Pierre A Kocher
- 期刊名称：《Briefings in Bioinformatics》
- RNA sequencing indels mutation alignment variant calling EGFR;
64.Computational models for predicting drug responses in cancer research

机译：预测癌症研究中药物反应的计算模型
- 作者：Francisco Azuaje
- 期刊名称：《Briefings in Bioinformatics》
- drug sensitivity computational prediction models cancer translational bioinformatics precision medicine;
65.Graphics processing units in bioinformatics computational biology and systems biology

机译：生物信息学计算生物学和系统生物学中的图形处理单元
- 作者：Marco S Nobile;Paolo Cazzaniga;Andrea Tangherloni;Daniela Besozzi
- 期刊名称：《Briefings in Bioinformatics》
- graphics processing units CUDA high-performance computing bioinformatics computational biology systems biology;
66.TBC2health: a database of experimentally validated health-beneficial effects of tea bioactive compounds

机译：TBC2health：经过实验验证的茶生物活性化合物对健康有益的数据库
- 作者：Shihua Zhang;Hongdong Xuan;Liang Zhang;Sicong Fu;Yijun Wang;Hua Yang;Yuling Tai;Youhong Song;Jinsong Zhang;Chi-Tang Ho;Shaowen Li;Xiaochun Wan
- 期刊名称：《Briefings in Bioinformatics》
- tea bioactive compound health benefit disease phenotype network;
67.Comparison of methods to detect differentially expressed genes between single-cell populations

机译：检测单细胞群体之间差异表达基因的方法比较
- 作者：Maria K Jaakkola;Fatemeh Seyednasrollah;Arfa Mehmood;Laura L Elo
- 期刊名称：《Briefings in Bioinformatics》
- single-cell comparison differential expression RNA-seq reproducibility;
68.Embracing an integromic approach to tissue biomarker research in cancer: Perspectives and lessons learned

机译：接受针对肿瘤组织生物标志物研究的整体方法：观点和经验教训
- 作者：Gerald Li;Peter Bankhead;Philip D Dunne;Paul G O’Reilly;Jacqueline A James;Manuel Salto-Tellez;Peter W Hamilton;Darragh G McArt
- 期刊名称：《Briefings in Bioinformatics》
- integromics big data biomarkers omics digital pathology interdisciplinary teamwork;
69.Ontology-based annotations and semantic relations in large-scale (epi)genomics data

机译：大规模（epi）基因组数据中基于本体的注释和语义关系
- 作者：Eugenia Galeota;Mattia Pelizzola
- 期刊名称：《Briefings in Bioinformatics》
- semantic annotation semantic similarity epigenetics transcription factor high-throughput sequencing natural language processing;
70.Heterogeneous molecular processes among the causes of how sequence similarity scores can fail to recapitulate phylogeny

机译：序列相似性评分如何无法概括系统发育的原因中的异构分子过程
- 作者：Stephen A Smith;James B Pease
- 期刊名称：《Briefings in Bioinformatics》
- phylogenetics sequence similarity BLAST rate heterogeneity phylostratigraphy compositional bias;
71.Development of a cloud-based Bioinformatics Training Platform

机译：开发基于云的生物信息学培训平台
- 作者：Jerico Revote;Nathan S Watson-Haigh;Steve Quenette;Blair Bethwaite;Annette McGrath;Catherine A Shang
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics training next-generation sequencing NGS cloud workshop;
72.Template-based protein–protein docking exploiting pairwise interfacial residue restraints

机译：基于模板的蛋白质-蛋白质对接利用成对界面残基限制
- 作者：Li C Xue;João P G L M Rodrigues;Drena Dobbs;Vasant Honavar;Alexandre M J J Bonvin
- 期刊名称：《Briefings in Bioinformatics》
- template-based modeling interface restrained docking CA-CA-guided docking AIR-guided docking refinement;
73.Tensor factorization toward precision medicine

机译：张量分解到精确医学
- 作者：Yuan Luo;Fei Wang;Peter Szolovits
- 期刊名称：《Briefings in Bioinformatics》
- tensor factorization precision medicine biomedical data mining multiple data modalities;
74.Zisland Explorer: detect genomic islands by combining homogeneity and heterogeneity properties

机译：Zisland Explorer：通过结合同质性和异质性属性来检测基因组岛
- 作者：Wen Wei;Feng Gao;Meng-Ze Du;Hong-Li Hua;Ju Wang;Feng-Biao Guo
- 期刊名称：《Briefings in Bioinformatics》
- genomic islands prediction homogeneity cumulative GC profile;
75.Towards an open collaborative reusable framework for sharing hands-on bioinformatics training workshops

机译：建立一个开放协作可重用的框架以共享动手生物信息学培训研讨会
- 作者：Nathan S Watson-Haigh;Jerico Revote;Radosław Suchecki;Sonika Tyagi;Susan M Corley;Catherine A Shang;Annette McGrath
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics;
- training;
- workshop;
- reusable;
- collaborative;
- open access;
76.Dimension reduction techniques for the integrative analysis of multi-omics data

机译：用于多组学数据集成分析的降维技术
- 作者：Chen Meng;*;Oana A. Zeleznik;*;Gerhard G. Thallinger;*;Bernhard Kuster;*;Amin M. Gholami;*;Aedín C. Culhane;*
- 期刊名称：《Briefings in Bioinformatics》
- multivariate analysis multi-omics data integration dimension reduction integrative genomics exploratory data analysis multi-assay;
77.Effect of lossy compression of quality scores on variant calling

机译：有损压缩质量得分对变量调用的影响
- 作者：Idoia Ochoa;Mikel Hernaez;Rachel Goldfeder;Tsachy Weissman;Euan Ashley
- 期刊名称：《Briefings in Bioinformatics》
- Genomic data;
- lossy compression;
- quality scores;
- variant calling;
78.A benchmark of gene expression tissue-specificity metrics

机译：基因表达组织特异性指标的基准
- 作者：Nadezda Kryuchkova-Mostacci;Marc Robinson-Rechavi
- 期刊名称：《Briefings in Bioinformatics》
- tissue specificity expression human mouse RNA-seq microarray;
79.Translational bioinformatics in the era of real-time biomedical health care and wellness data streams

机译：实时生物医学医疗保健和健康数据流时代的转化生物信息学
- 作者：Khader Shameer;Marcus A Badgeley;Riccardo Miotto;Benjamin S Glicksberg;Joseph W Morgan;Joel T Dudley
- 期刊名称：《Briefings in Bioinformatics》
- scientific wellness wellcare clinical decision support health monitoring individualized medicine wearables health information technology;
80.A comprehensive comparison of tools for differential ChIP-seq analysis

机译：差分ChIP-seq分析工具的全面比较
- 作者：Sebastian Steinhauser;*;Nils Kurzawa;*;Roland Eils;*;Carl Herrmann;*
- 期刊名称：《Briefings in Bioinformatics》
- ChIP-seq differential analysis software;
81.A proteogenomic approach to understand splice isoform functions through sequence and expression-based computational modeling

机译：一种蛋白质组学方法可通过基于序列和基于表达的计算建模来了解剪接异构体功能
- 作者：Hong-Dong Li;*;Gilbert S. Omenn;*;Yuanfang Guan;*
- 期刊名称：《Briefings in Bioinformatics》
- alternatively spliced isoform function prediction selection pressure isoform expression functional networks;
82.In the loop: promoter–enhancer interactions and bioinformatics

机译：循环中：启动子-增强子相互作用和生物信息学
- 作者：Antonio Mora;*;Geir Kjetil Sandve;*;Odd Stokke Gabrielsen;*;Ragnhild Eskeland;*
- 期刊名称：《Briefings in Bioinformatics》
- Chromatin loops chromosome conformation capture CTCF enhancer prediction histone modifications promoter–enhancer interactions SNPs transcription factories;
83.Interpreting functional effects of coding variants: challenges in proteome-scale prediction annotation and assessment

机译：解释编码变体的功能效果：蛋白质组规模预测注释和评估的挑战
- 作者：Khader Shameer;Lokesh P. Tripathi;Krishna R. Kalari;Joel T. Dudley;Ramanathan Sowdhamini
- 期刊名称：《Briefings in Bioinformatics》
- human genome functional variant human variation variant interpretation mutation human proteome non-synonymous mutations prediction algorithms functional genomics sequence analysis structure analysis;
84.Pathway Tools version 19.0 update: software for pathway/genome informatics and systems biology

机译：Pathway Tools版本19.0更新：用于途径/基因组信息学和系统生物学的软件
- 作者：Peter D. Karp;*;Mario Latendresse;*;Suzanne M. Paley;*;Markus Krummenacker;*;Quang D. Ong;*;Richard Billington;*;Anamika Kothari;*;Daniel Weaver;*;Thomas Lee;*;Pallavi Subhraveti;*;Aaron Spaulding;*;Carol Fulcher;*;Ingrid M. Keseler;*;Ron Caspi;*
- 期刊名称：《Briefings in Bioinformatics》
- metabolic pathways metabolic models systems biology computational genomics;
85.Public data and open source tools for multi-assay genomic investigation of disease

机译：用于疾病多测定基因组研究的公共数据和开源工具
- 作者：Lavanya Kannan;*;Marcel Ramos;*;Angela Re;*;Nehme El-Hachem;*;Zhaleh Safikhani;*;Deena M.A. Gendoo;*;Sean Davis;*;David Gomez-Cabrero;*;Robert Castelo;*;Kasper D. Hansen;*;Vincent J. Carey;*;Martin Morgan;*;Aedín C. Culhane;*;Benjamin Haibe-Kains;*;Levi Waldron;*
- 期刊名称：《Briefings in Bioinformatics》
- multiple assays (multi-assays) public data bioconductor integrative genomics cancer pharmacogenomics omics;
86.Statistical methods for detecting differentially methylated regions based on MethylCap-seq data

机译：基于MethylCap-seq数据检测差异甲基化区域的统计方法
- 作者：Deepak N. Ayyala;*;David E. Frankhouser;*;Javkhlan-Ochir Ganbat;*;Guido Marcucci;*;Ralf Bundschuh;*;Pearlly Yan;*;Shili Lin;*
- 期刊名称：《Briefings in Bioinformatics》
- differentially methylated regions methylCap-seq high dimensionality mean vector test;
87.MST2-RASSF protein–protein interactions through SARAH domains

机译：MST2-RASSF蛋白通过SARAH结构域的蛋白相互作用
- 作者：Goar Sánchez-Sanz;David Matallanas;Lan K. Nguyen;Boris N. Kholodenko;Edina Rosta;Walter Kolch;Nicolae-Viorel Buchete
- 期刊名称：《Briefings in Bioinformatics》
- competing protein interactions SARAH domains signaling switches apoptosis cell fate decision molecular dynamics;
88.Recent Advances and Emerging Applications in Text and Data Mining for Biomedical Discovery

机译：用于生物医学发现的文本和数据挖掘中的最新进展和新兴应用
- 作者：Graciela H. Gonzalez;*;Tasnia Tahsin;*;Britton C. Goodale;*;Anna C. Greene;*;Casey S. Greene;*
- 期刊名称：《Briefings in Bioinformatics》
- text mining data mining biomedical discovery gene prioritization pharmacogenomics toxicology;
89.Systems medicine of inflammaging

机译：系统发炎药
- 作者：Gastone C. Castellani;*;Giulia Menichetti;*;Paolo Garagnani;*;Maria Giulia Bacalini;*;Chiara Pirazzini;*;Claudio Franceschi;*;Sebastiano Collino;*;Claudia Sala;*;Daniel Remondini;*;Enrico Giampieri;*;Ettore Mosca;*;Matteo Bersanelli;*;Silvia Vitali;*;Italo Faria do Valle;*;Pietro Liò;*;Luciano Milanesi;*
- 期刊名称：《Briefings in Bioinformatics》
- propagation ecological model networks multilayer networks inflammation multi-scale;
90.Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data

机译：从外显子组和RNA测序数据检测线粒体序列作图策略和线粒体变异检测的实用性
- 作者：Pan Zhang;David C. Samuels;Brian Lehmann;Thomas Stricker;Jennifer Pietenpol;Yu Shyr;Yan Guo
- 期刊名称：《Briefings in Bioinformatics》
- mitochondria data mining SNP heteroplasmy;
91.Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases

机译：神经退行性疾病因果模型中遗传方差信息的推理
- 作者：Mufassra Naz;*;Alpha Tom Kodamullil;*;Martin Hofmann-Apitius;*
- 期刊名称：《Briefings in Bioinformatics》
- BEL model Alzheimer’s disease genetic variants GWAS causal reasoning cause-and-effect;
92.Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR

机译：通过定量实时RT-PCR获得的循环microRNA表达数据的标准化
- 作者：Francesco Marabita;*;Paola de Candia;*;Anna Torri;*;Jesper Tegnér;*;Sergio Abrignani;*;Riccardo L. Rossi;*
- 期刊名称：《Briefings in Bioinformatics》
- normalization circulating miRNA qPCR reference genes geNorm Normfinder;
93.Evaluation of somatic copy number estimation tools for whole-exome sequencingdata

机译：评估用于全外显子测序的体细胞拷贝数估计工具数据
- 作者：Jae-Yong Nam;Nayoung K. D. Kim;Sang Cheol Kim;Je-Gun Joung;Ruibin Xi;Semin Lee;Peter J. Park;Woong-Yang Park
- 期刊名称：《Briefings in Bioinformatics》
- CNV prediction somatic alterations the cancer genome atlas CNV algorithms;
94.VCF-Miner: GUI-based application for mining variants and annotations stored in VCF files

机译：VCF-Miner：基于GUI的应用程序用于挖掘存储在VCF文件中的变体和注释
- 作者：Steven N. Hart;*;Patrick Duffy;*;Daniel J. Quest;*;Asif Hossain;*;Mike A Meiners;*;Jean-Pierre Kocher;*
- 期刊名称：《Briefings in Bioinformatics》
- bioinformatics genomics analysis software user interface VCF;
95.Empirical comparison of structure-based pathway methods

机译：基于结构的途径方法的实证比较
- 作者：Maria K. Jaakkola;*;Laura L. Elo;*
- 期刊名称：《Briefings in Bioinformatics》
- pathway analysis pathway structure comparison functional genomics statistical analysis;
96.Improving protein identification from tandem mass spectrometry data by one-step methods and integrating data from other platforms

机译：通过一步方法并结合其他平台的数据来改善串联质谱数据中的蛋白质鉴定
- 作者：Sinjini Sikdar;Ryan Gill;Susmita Datta
- 期刊名称：《Briefings in Bioinformatics》
- protein identification tandem mass spectrometry one-step processes;
97.Using prior knowledge from cellular pathways and molecular networks for diagnostic specimen classification

机译：利用细胞途径和分子网络的先验知识进行诊断标本分类
- 作者：Enrico Glaab;*
- 期刊名称：《Briefings in Bioinformatics》
- biomarker modeling pathway analysis network analysis machine learning cross-study analysis;
98.A roadmap to multifactor dimensionality reduction methods

机译：多因素降维方法路线图
- 作者：Damian Gola;*;Jestinah M. Mahachie John;*;Kristel van Steen;*;Inke R. König;*
- 期刊名称：《Briefings in Bioinformatics》
- interaction epistasis multifactor dimensionality reduction machine learning data mining;
99.Community challenges in biomedical text mining over 10 years: success failure and the future

机译：十年来生物医学文本挖掘中的社区挑战：成功失败和未来
- 作者：Chung-Chi Huang;*;Zhiyong Lu;*
- 期刊名称：《Briefings in Bioinformatics》
- biomedical natural language processing (BioNLP) BioNLP challenges BioNLP shared tasks critical assessment text mining;
100.Crowdsourcing in biomedicine: challenges and opportunities

机译：生物医学众包：挑战与机遇
- 作者：Ritu Khare;*;Benjamin M. Good;*;Robert Leaman;*;Andrew I. Su;*;Zhiyong Lu;*
- 期刊名称：《Briefings in Bioinformatics》
- Amazon Mechanical Turk big data mining biomedicine community challenges crowdsourcing games;