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Human Gene Therapy Methods

【机译】：人类基因治疗的方法

ISSN：-
出版周期：Bimonthly
语言：English

起始发布年份：2011
出版者：New Rochelle, NY : Mary Ann Liebert
出版地：United States

NLM刊名缩写：Hum Gene Ther Methods

数据库引入：PubMed: v23n1, Feb. 2012-v30n6, Dec. 2019

MeSH词表主题词：Genetic Therapy*

备注：Issue for Feb. 2012 has title: Human gene therapy. Part B. Methods. Some articles展开▼

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1.Standardized Scalable and Timely Flexible Adeno-Associated Virus Vector Production Using Frozen High-Density HEK-293 Cell Stocks and CELLdiscs

机译：使用冷冻的高密度HEK-293细胞库存和CELLdiscs标准化可扩展且及时灵活的腺相关病毒载体生产
- 作者：Benjamin Strobel;Kai Zuckschwerdt;Gudrun Zimmermann;Christine Mayer;Ruth Eytner;Philipp Rechtsteiner;Sebastian Kreuz;Thorsten Lamla
- 期刊名称：《Human Gene Therapy Methods》
- cell factories cell stacks clinical process development biotechnology large-scale AAV production gene therapy;
2.The Functional Effect of Repeated Cryopreservation on Transduced CD34+ Cells from Patients with Thalassemia

机译：反复冷冻保存对地中海贫血症患者转导的CD34 +细胞的功能作用
- 作者：Garyfalia Karponi;Penelope-Georgia Papayanni;Fani Zervou;Asimina Bouinta;Achilles Anagnostopoulos;Evangelia Yannaki
- 期刊名称：《Human Gene Therapy Methods》
3.Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space

机译：重组腺相关病毒缓慢注入小鼠脑脊液空间。
- 作者：Dan Wang;Jia Li;Karen Tran;Daniel R. Burt;Li Zhong;Guangping Gao
- 期刊名称：《Human Gene Therapy Methods》
4.Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies

机译：球蛋白链对血红蛋白病基因和细胞治疗的快速灵敏评估
- 作者：Constantinos C. Loucari;Petros Patsali;Thamar B. van Dijk;Coralea Stephanou;Panayiota Papasavva;Maria Zanti;Ryo Kurita;Yukio Nakamura;Soteroulla Christou;Maria Sitarou;Sjaak Philipsen;Carsten W. Lederer;Marina Kleanthous
- 期刊名称：《Human Gene Therapy Methods》
5.Manufacture of Third-Generation Lentivirus for Preclinical Use with Process Development Considerations for Translation to Good Manufacturing Practice

机译：生产用于临床前的第三代慢病毒并考虑将过程开发考虑为良好生产规范的翻译
- 作者：Carolina Gándara;Valerie Affleck;Elizabeth Ann Stoll
- 期刊名称：《Human Gene Therapy Methods》
6.Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency

机译：慢病毒介导的基因转移对CSF2RA缺陷的功能和安全性
- 作者：Miriam Hetzel;Takuji Suzuki;Anna Rafiei Hashtchin;Paritha Arumugam;Brenna Carey;Marc Schwabbauer;Alexandra Kuhn;Johann Meyer;Axel Schambach;Johannes Van Der Loo;Thomas Moritz;Bruce C. Trapnell;Nico Lachmann
- 期刊名称：《Human Gene Therapy Methods》
7.Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines

机译：使用稳定的HEK293SF生产细胞株可扩展的慢病毒载体生产
- 作者：Aziza P. Manceur;Howard Kim;Vanja Misic;Nadejda Andreev;July Dorion-Thibaudeau;Stéphane Lanthier;Alice Bernier;Sonia Tremblay;Anne-Marie Gélinas;Sophie Broussau;Rénald Gilbert;Sven Ansorge
- 期刊名称：《Human Gene Therapy Methods》
8.Multimodal Lentiviral Vectors for Pharmacologically Controlled Switching Between Constitutive Single Gene Expression and Tetracycline-Regulated Multiple Gene Collaboration

机译：组成型单基因表达与四环素调节的多基因协作之间药理控制切换的多模式慢病毒载体。
- 作者：Maike Stahlhut;Axel Schambach;Olga S. Kustikova
- 期刊名称：《Human Gene Therapy Methods》
- lentiviral vectors constitutive and tetracycline-regulated genetic modification of HSCs and HPCs fate tracking;
9.CAR T-Cell Therapy: Progress and Prospects

机译：CAR T细胞疗法：进展和前景
- 作者：Olivia Wilkins;Allison M. Keeler;Terence R. Flotte
- 期刊名称：《Human Gene Therapy Methods》
10.Correction to: Hum Gene Ther Methods 2016;27:209–218

机译：更正为：Hum Gene Ther Methods 2016； 27：209–218
- 期刊名称：《Human Gene Therapy Methods》
11.Sodium Chloride Enhances Recombinant Adeno-Associated Virus Production in a Serum-Free Suspension Manufacturing Platform Using the Herpes Simplex Virus System

机译：氯化钠使用单纯疱疹病毒系统在无血清悬浮液生产平台中增强重组腺相关病毒的生产
- 作者：Laura Adamson-Small;Mark Potter;Barry J. Byrne;Nathalie Clément
- 期刊名称：《Human Gene Therapy Methods》
12.Assaying the Stability and Inactivation of AAV Serotype 1 Vectors

机译：测定AAV血清型1载体的稳定性和失活
- 作者：Douglas B. Howard;Brandon K. Harvey
- 期刊名称：《Human Gene Therapy Methods》
13.Characteristics of Minimally Oversized Adeno-Associated Virus Vectors Encoding Human Factor VIII Generated Using Producer Cell Lines and Triple Transfection

机译：使用生产细胞系和三重转染产生的编码人因子VIII的最小超大腺伴随病毒载体的特征
- 作者：Bindu Nambiar;Cathleen Cornell Sookdeo;Patricia Berthelette;Robert Jackson;Susan Piraino;Brenda Burnham;Shelley Nass;David Souza;Catherine R. ORiordan;Karen A. Vincent;Seng H. Cheng;Donna Armentano;Sirkka Kyostio-Moore
- 期刊名称：《Human Gene Therapy Methods》
14.A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies

机译：快速细胞扩增过程用于生产自体工程CAR-T细胞疗法
- 作者：Tangying Lily Lu;Omar Pugach;Robert Somerville;Steven A. Rosenberg;James N. Kochenderfer;Marc Better;Steven A. Feldman
- 期刊名称：《Human Gene Therapy Methods》
15.Adeno-Associated Virus 5 Transduces Adipose-Derived Stem Cells with Greater Efficacy Than Other Adeno-Associated Viral Serotypes

机译：腺相关病毒5转导脂肪来源的干细胞比其他腺相关病毒血清型具有更高的功效。
- 作者：Priyanka Sharma;Sunishka M. Wimalawansa;Gregory C. Gould;R. Michael Johnson;Katherine J.D.A. Excoffon
- 期刊名称：《Human Gene Therapy Methods》
16.Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope

机译：表达鸟苷酸环化酶C和PADRE T辅助抗原决定簇的复制缺陷型重组腺病毒5型血清型疫苗的临床前评价
- 作者：Adam E. Snook;Trevor R. Baybutt;Terry Hyslop;Scott A. Waldman
- 期刊名称：《Human Gene Therapy Methods》
17.Application of Droplet Digital PCR for Estimating Vector Copy Number States in Stem Cell Gene Therapy

机译：液滴数字PCR在干细胞基因治疗中估计载体拷贝数状态的应用
- 作者：Huan-Ting Lin;Takashi Okumura;Yukinori Yatsuda;Satoru Ito;Hiromitsu Nakauchi;Makoto Otsu
- 期刊名称：《Human Gene Therapy Methods》
18.A Partial E3 Deletion in Replication-Defective Adenoviral Vectors Allows for Stable Expression of Potentially Toxic Transgene Products

机译：复制缺陷型腺病毒载体中的部分E3删除允许潜在有毒的转基因产物的稳定表达
- 作者：Larissa H. Haut;Amanda L. Gill;Raj K. Kurupati;Ang Bian;Yan Li;Wynetta Giles-Davis;Zhiquan Xiang;Xiang Yang Zhou;Hildegund C. J. Ertl
- 期刊名称：《Human Gene Therapy Methods》
19.Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses

机译：进一步减少剂量的高效转导的优化AAV血清型载体的开发
- 作者：Chen Ling;Baozheng Li;Wenqin Ma;Arun Srivastava
- 期刊名称：《Human Gene Therapy Methods》
20.Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene

机译：逆转录病毒复制载体的广泛复制可以扩大脑心肌炎病毒内部核糖体进入位点的隆起并改变下游转基因的翻译效率。
- 作者：Amy H. Lin;Yanzheng Liu;Cynthia Burrascano;Kathrina Cunanan;Christopher R. Logg;Joan M. Robbins;Noriyuki Kasahara;Harry Gruber;Carlos Ibañez;Douglas J. Jolly
- 期刊名称：《Human Gene Therapy Methods》
21.Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types

机译：逆转录病毒复制载体传递胞嘧啶脱氨酶导致多种人类癌症类型的靶向5-氟尿嘧啶介导的细胞毒性。
- 作者：Chris G. Twitty;Oscar R. Diago;Daniel J. Hogan;Cindy Burrascano;Carlos E. Ibanez;Douglas J. Jolly;Derek Ostertag
- 期刊名称：《Human Gene Therapy Methods》
22.Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2 But Not AAV8 Vectors in Murine Hepatocytes In Vivo

机译：表面暴露的赖氨酸残基的定点诱变导致小鼠肝细胞体内的AAV2（而非AAV8）载体的转导提高
- 作者：Baozheng Li;Wenqin Ma;Chen Ling;Kim Van Vliet;Lin-Ya Huang;Mavis Agbandje-McKenna;Arun Srivastava;George V. Aslanidi
- 期刊名称：《Human Gene Therapy Methods》
23.Modified Genomic Sequencing PCR Using the MiSeq Platform to Identify Retroviral Integration Sites

机译：使用MiSeq平台鉴定逆转录病毒整合位点的改良基因组测序PCR
- 作者：Dustin T. Rae;Casey P. Collins;Jonah D. Hocum;Diana L. Browning;Grant D. Trobridge
- 期刊名称：《Human Gene Therapy Methods》
24.Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy

机译：通过视频显微镜观察人成肌细胞和间充质干细胞的相互作用
- 作者：Amanda B. Black;Heather Dahlenburg;Karen Pepper;Catherine Nacey;Suzanne Pontow;Maggie A. Kuhn;Peter C. Belafsky;Jan A. Nolta
- 期刊名称：《Human Gene Therapy Methods》
25.Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications

机译：用于临床前应用的重组腺相关病毒载体基于氯化铯和碘克沙醇的纯化的比较分析
- 作者：Benjamin Strobel;Felix D. Miller;Wolfgang Rist;Thorsten Lamla
- 期刊名称：《Human Gene Therapy Methods》
26.Progress with Recombinant Adeno-Associated Virus Vectors for Gene Therapy of Alpha-1 Antitrypsin Deficiency

机译：重组腺相关病毒载体用于α-1抗胰蛋白酶缺乏症基因治疗的进展
- 作者：Alisha M. Gruntman;Terence R. Flotte
- 期刊名称：《Human Gene Therapy Methods》
27.Preexisting Neutralizing Antibodies to Adeno-Associated Virus Capsids in Large Animals Other Than Monkeys May Confound In Vivo Gene Therapy Studies

机译：除猴子以外的大型动物中与腺相关病毒衣壳的既有中和抗体可能会混淆体内基因治疗研究
- 作者：Roberto Calcedo;Judith Franco;Qiuyue Qin;Dean W. Richardson;Jeffery B. Mason;Surina Boyd;James M. Wilson
- 期刊名称：《Human Gene Therapy Methods》
28.Systematic Comparison and Validation of Quantitative Real-Time PCR Methods for the Quantitation of Adeno-Associated Viral Products

机译：实时定量PCR方法对腺相关病毒产品定量的系统比较和验证
- 作者：Natalie Jayne Werling;Stifani Satkunanathan;Robin Thorpe;Yuan Zhao
- 期刊名称：《Human Gene Therapy Methods》
29.Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System

机译：体外报告系统测定抗腺相关病毒载体中和抗体滴度
- 作者：Amine Meliani;Christian Leborgne;Sabrina Triffault;Laurence Jeanson-Leh;Philippe Veron;Federico Mingozzi
- 期刊名称：《Human Gene Therapy Methods》
30.Quantitative Shearing Linear Amplification Polymerase Chain Reaction: An Improved Method for Quantifying Lentiviral Vector Insertion Sites in Transplanted Hematopoietic Cell Systems

机译：定量剪切线性扩增聚合酶链反应：一种用于量化移植的造血细胞系统中慢病毒载体插入位点的改进方法。
- 作者：Sheng Zhou;Melissa A. Bonner;Yong-Dong Wang;Samuel Rapp;Suk See De Ravin;Harry L. Malech;Brian P. Sorrentino
- 期刊名称：《Human Gene Therapy Methods》
31.Superior Long-Term Repopulating Capacity of G-CSF+Plerixafor-Mobilized Blood: Implications for Stem Cell Gene Therapy by Studies in the Hbbth-3 Mouse Model

机译：G-CSF + Plerixa用于动员血液的卓越长期繁殖能力：对Hbbth-3小鼠模型的研究对干细胞基因治疗的意义
- 作者：Nikoleta Psatha;Eleni Sgouramali;Antonios Gkountis;Athanasios Siametis;Panayotis Baliakas;Varnavas Constantinou;Evangelia Athanasiou;Minas Arsenakis;Achilles Anagnostopoulos;Thalia Papayannopoulou;George Stamatoyannopoulos;Evangelia Yannaki
- 期刊名称：《Human Gene Therapy Methods》
32.Repair of Single-Point Mutations by Polypurine Reverse Hoogsteen Hairpins

机译：修复多嘌呤反向Hoogsteen发夹单点突变
- 作者：Anna Solé;Xenia Villalobos;Carlos J. Ciudad;Véronique Noé
- 期刊名称：《Human Gene Therapy Methods》
33.Copackaging of Multiple Adeno-Associated Viral Vectors in a Single Production Step

机译：在单个生产步骤中多个腺相关病毒载体的共包装
- 作者：Phillip A. Doerfler;Barry J. Byrne;Nathalie Clément
- 期刊名称：《Human Gene Therapy Methods》
34.Manufacture of Gene-Modified Human T-Cells with a Memory Stem/Central Memory Phenotype

机译：具有记忆茎/中央记忆表型的基因修饰的人类T细胞的制造
- 作者：Raquel Gomez-Eerland;Bastiaan Nuijen;Bianca Heemskerk;Nienke van Rooij;Joost H. van den Berg;Jos H. Beijnen;Wolfgang Uckert;Pia Kvistborg;Ton N. Schumacher;John B.A.G. Haanen;Annelies Jorritsma
- 期刊名称：《Human Gene Therapy Methods》
35.Efficient Production of Dual Recombinant Adeno-Associated Viral Vectors for Factor VIII Delivery

机译：有效生产双重重组腺相关病毒载体的因子VIII传递。
- 作者：Qizhao Wang;Biao Dong;Jenni Firrman;Sean Roberts;Andrea Rossi Moore;Wenjing Cao;Yong Diao;Philipp Kapranov;Ruian Xu;Weidong Xiao
- 期刊名称：《Human Gene Therapy Methods》
36.Use of the piggyBac Transposon to Create Stable Packaging Cell Lines for the Production of Clinical-Grade Self-Inactivating γ-Retroviral Vectors

机译：使用piggyBac转座子创建稳定的包装细胞系以生产临床级别的自灭活γ-逆转录病毒载体
- 作者：Steven A. Feldman;Hui Xu;Mary A. Black;Tristen S. Park;Paul F. Robbins;James N. Kochenderfer;Richard A. Morgan;Steven A. Rosenberg
- 期刊名称：《Human Gene Therapy Methods》
37.A New Method for Generating Insulin-Secreting Cells from Human Pancreatic Epithelial Cells After Islet Isolation Transformed by NeuroD1

机译：从NeuroD1转化胰岛分离后从人胰腺上皮细胞生成胰岛素分泌细胞的新方法
- 作者：Masayuki Shimoda;Shuyuan Chen;Hirofumi Noguchi;Morihito Takita;Koji Sugimoto;Takeshi Itoh;Daisuke Chujo;Shuichi Iwahashi;Bashoo Naziruddin;Marlon F. Levy;Shinichi Matsumoto;Paul A. Grayburn
- 期刊名称：《Human Gene Therapy Methods》
38.In Utero Lung Gene Transfer Using Adeno-Associated Viral and Lentiviral Vectors in Mice

机译：小鼠腺相关病毒和慢病毒载体在子宫肺基因转移中的应用
- 作者：Luc Joyeux;Enrico Danzer;Maria P. Limberis;Philip W. Zoltick;Antoneta Radu;Alan W. Flake;Marcus G. Davey
- 期刊名称：《Human Gene Therapy Methods》
39.Fast and Efficient Multitransgenic Modification of Human Pluripotent Stem Cells

机译：人多能干细胞的快速和高效的多转基因修饰。
- 作者：Kristin Schwanke;Sylvia Merkert;Henning Kempf;Susann Hartung;Monica Jara-Avaca;Christian Templin;Gudrun Göhring;Axel Haverich;Ulrich Martin;Robert Zweigerdt
- 期刊名称：《Human Gene Therapy Methods》
40.Concurrent measures of fusion and transduction efficiency of primary CD34+ cells with human immunodeficiency virus 1-based lentiviral vectors reveal different effects of transduction enhancers

机译：同时检测基于人免疫缺陷病毒1的慢病毒载体对原代CD34 +细胞融合和转导效率的方法揭示了转导增强子的不同作用
- 作者：Dina Ingrao;Saliha Majdoul;Ababacar Seye;Anne Galy;David Fenard
- 期刊名称：《Human Gene Therapy Methods》
41.Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR

机译：液滴数字PCR绝对测定单链和自互补腺相关病毒载体基因组滴度
- 作者：Martin Lock;Mauricio R. Alvira;Shu-Jen Chen;James M. Wilson
- 期刊名称：《Human Gene Therapy Methods》
42.Improved Animal Models for Testing Gene Therapy for Atherosclerosis

机译：用于测试动脉粥样硬化基因治疗的改良动物模型
- 作者：Liang Du;Jingwan Zhang;Guido R.Y. De Meyer;Rowan Flynn;David A. Dichek
- 期刊名称：《Human Gene Therapy Methods》
43.Laser Photocoagulation Enhances Adeno-Associated Viral Vector Transduction of Mouse Retina

机译：激光光凝增强小鼠视网膜的腺相关病毒载体转导。
- 作者：Si Hyung Lee;Peter Colosi;Heuiran Lee;Young-Hoon Ohn;Sung-Woon Kim;Hyung Woo Kwak;Tae Kwann Park
- 期刊名称：《Human Gene Therapy Methods》
44.K137R Mutation on Adeno-Associated Viral Capsids Had Minimal Effect on Enhancing Gene Delivery In Vivo

机译：腺相关病毒衣壳上的K137R突变对增强体内基因传递的影响最小。
- 作者：Chunping Qiao;Chengwen Li;Chunxia Zhao;Jianbin Li;Tao Bian;Joshua Grieger;Juan Li;R. Jude Samulski;Xiao Xiao
- 期刊名称：《Human Gene Therapy Methods》
45.Adeno-Associated Virus Enhances Wild-Type and Oncolytic Adenovirus Spread

机译：腺相关病毒增强了野生型和溶瘤性腺病毒的传播
- 作者：Eduardo Laborda;Cristina Puig-Saus;Manel Cascalló;Miguel Chillón;Ramon Alemany
- 期刊名称：《Human Gene Therapy Methods》
46.Characterization of the Properties of Seven Promoters in the Motor Cortex of Rats and Monkeys After Lentiviral Vector-Mediated Gene Transfer

机译：慢病毒载体介导的基因转移后大鼠和猴子运动皮质中七个启动子的特性表征
- 作者：Masae Yaguchi;Yohei Ohashi;Tadashi Tsubota;Ayana Sato;Kenji W. Koyano;Ningqun Wang;Yasushi Miyashita
- 期刊名称：《Human Gene Therapy Methods》
47.Noninvasive Imaging of Hypoxia-Inducible Factor-1α Gene Therapy for Myocardial Ischemia

机译：缺氧诱导因子-1α基因治疗心肌缺血的无创成像
- 作者：Ian Y. Chen;Olivier Gheysens;Zongjin Li;Julia A. Rasooly;Qian Wang;Ramasamy Paulmurugan;Jarrett Rosenberg;Martin Rodriguez-Porcel;Juergen K. Willmann;David S. Wang;Christopher H. Contag;Robert C. Robbins;Joseph C. Wu;Sanjiv S. Gambhir
- 期刊名称：《Human Gene Therapy Methods》
48.Effect of Fetal Bovine Serum on Foamy and Lentiviral Vector Production

机译：胎牛血清对泡沫和慢病毒载体生产的影响
- 作者：John M. Powers;Grant D. Trobridge
- 期刊名称：《Human Gene Therapy Methods》
49.Ex Vivo Generation of Highly Purified and Activated Natural Killer Cells from Human Peripheral Blood

机译：从人外周血中高度纯化和活化的天然杀伤细胞的体内生成
- 作者：Satoru Saito;Yui Harada;Yosuke Morodomi;Mitsuho Onimaru;Kumi Yoshida;Ryoichi Kyuragi;Hisahiro Matsubara;Yoshikazu Yonemitsu
- 期刊名称：《Human Gene Therapy Methods》
50.Transduction of the Central Nervous System After Intracerebroventricular Injection of Adeno-Associated Viral Vectors in Neonatal and Juvenile Mice

机译：脑室内注射腺相关病毒载体在新生小鼠和幼年小鼠中对中枢神经系统的转导
- 作者：Shervin Gholizadeh;Sujeenthar Tharmalingam;Margarita E. MacAldaz;David R. Hampson
- 期刊名称：《Human Gene Therapy Methods》
51.A Systematic Approach to the Establishment and Characterization of Endothelial Progenitor Cells for Gene Therapy

机译：用于基因治疗的内皮祖细胞的建立和表征的系统方法
- 作者：Natalie Jayne Werling;Robin Thorpe;Yuan Zhao
- 期刊名称：《Human Gene Therapy Methods》
52.The Chicken Hypersensitivity Site 4 Core Insulator Blocks Promoter Interference in Lentiviral Vectors

机译：鸡超敏部位4核心绝缘子阻止慢病毒载体中的启动子干扰。
- 作者：Naoya Uchida;Hideki Hanawa;Motoko Yamamoto;Takashi Shimada
- 期刊名称：《Human Gene Therapy Methods》
53.Targeted Modifications in Adeno-Associated Virus Serotype 8 Capsid Improves Its Hepatic Gene Transfer Efficiency In Vivo

机译：腺相关病毒血清型8衣壳的靶向修饰可提高其体内肝基因转移效率。
- 作者：Dwaipayan Sen;Rupali A Gadkari;Govindarajan Sudha;Nishanth Gabriel;Yesupatham Sathish Kumar;Ruchita Selot;Rekha Samuel;Sumathi Rajalingam;V. Ramya;Sukesh C. Nair;Narayanaswamy Srinivasan;Alok Srivastava;Giridhara R. Jayandharan
- 期刊名称：《Human Gene Therapy Methods》
54.Bioengineering of AAV2 Capsid at Specific Serine Threonine or Lysine Residues Improves Its Transduction Efficiency in Vitro and in Vivo

机译：在特定的丝氨酸苏氨酸或赖氨酸残基上进行AAV2衣壳的生物工程改良可提高其体内外的转导效率。
- 作者：Nishanth Gabriel;Sangeetha Hareendran;Dwaipayan Sen;Rupali A. Gadkari;Govindarajan Sudha;Ruchita Selot;Mansoor Hussain;Ramya Dhaksnamoorthy;Rekha Samuel;Narayanaswamy Srinivasan;Alok Srivastava;Giridhara R. Jayandharan
- 期刊名称：《Human Gene Therapy Methods》
55.Induction of Aberrant Vascular Growth But Not of Normal Angiogenesis by Cell-Based Expression of Different Doses of Human and Mouse VEGF Is Species-Dependent

机译：通过基于细胞的不同剂量的人和小鼠VEGF的细胞表达诱导异常血管生长但不能正常血管生成是物种依赖性的
- 作者：Edin Mujagic;Roberto Gianni-Barrera;Marianna Trani;Abdulsamie Patel;Lorenz Gürke;Michael Heberer;Thomas Wolff;Andrea Banfi
- 期刊名称：《Human Gene Therapy Methods》
56.Retargeting Vesicular Stomatitis Virus Glycoprotein Pseudotyped Lentiviral Vectors with Enhanced Stability by In Situ Synthesized Polymer Shell

机译：通过原位合成的聚合物外壳提高稳定性的重定向水泡性口腔炎病毒糖蛋白假型慢病毒载体。
- 作者：Min Liang;Ming Yan;Yunfeng Lu;Irvin S.Y. Chen
- 期刊名称：《Human Gene Therapy Methods》
57.Comparison of Different Suicide-Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells

机译：不同自杀基因策略改善转基因T细胞安全性的比较
- 作者：Virna Marin;Elisabetta Cribioli;Brian Philip;Sarah Tettamanti;Irene Pizzitola;Andrea Biondi;Ettore Biagi;Martin Pule
- 期刊名称：《Human Gene Therapy Methods》
58.Development of an Equine-Tropic Replication-Competent Lentivirus Assay for Equine Infectious Anemia Virus-Based Lentiviral Vectors

机译：基于马传染性贫血病毒的慢病毒载体马属复制能力慢病毒检测方法的开发
- 作者：Daniel C. Farley;Richard Bannister;Marie A. Leroux-Carlucci;Nerys E. Evans;James E. Miskin;Kyriacos A. Mitrophanous
- 期刊名称：《Human Gene Therapy Methods》
59.Correlates Between Host and Viral Transcriptional Program Associated with Different Oncolytic Vaccinia Virus Isolates

机译：与宿主和病毒转录程序与不同的溶瘤痘苗病毒分离株相关联
- 作者：Jennifer Reinboth;Maria L. Ascierto;Nanhai G. Chen;Qian Zhang;Yong A. Yu;Richard J. Aguilar;Rafael Carretero;Andrea Worschech;Yingdong Zhao;Ena Wang;Francesco M. Marincola;Aladar A. Szalay
- 期刊名称：《Human Gene Therapy Methods》
60.Safety Profile of Gutless Adenovirus Vectors Delivered into the Normal Brain Parenchyma: Implications for a Glioma Phase 1 Clinical Trial

机译：胆汁腺病毒载体安全性概况交付正常脑实质：对胶质瘤1期临床试验的影响。
- 作者：A.K.M. Ghulam Muhammad;Weidong Xiong;Mariana Puntel;Catherine Farrokhi;Kurt M. Kroeger;Alireza Salem;Liliana Lacayo;Robert N. Pechnick;Kyle R. Kelson;Donna Palmer;Philip Ng;Chunyan Liu;Pedro R. Lowenstein;Maria G. Castro
- 期刊名称：《Human Gene Therapy Methods》
61.Restricted Transgene Expression in the Brain with Cell-Type Specific Neuronal Promoters

机译：细胞类型特定的神经元启动子在大脑中限制的转基因表达。
- 作者：Aurélie Delzor;Noelle Dufour;Fanny Petit;Martine Guillermier;Diane Houitte;Gwennaelle Auregan;Emmanuel Brouillet;Philippe Hantraye;Nicole Déglon
- 期刊名称：《Human Gene Therapy Methods》
62.Magnetic-Activated Cell Sorting of TCR-Engineered T Cells Using tCD34 as a Gene Marker but Not Peptide–MHC Multimers Results in Significant Numbers of Functional CD4+ and CD8+ T Cells

机译：使用tCD34作为基因标记而非肽MHC多聚体对TCR工程T细胞进行磁激活细胞分选导致大量功能性CD4 +和CD8 + T细胞
- 作者：Coen Govers;Cor Berrevoets;Elike Treffers-Westerlaken;Marieke Broertjes;Reno Debets
- 期刊名称：《Human Gene Therapy Methods》
63.Limitations of Encapsidation of Recombinant Self-Complementary Adeno-Associated Viral Genomes in Different Serotype Capsids and Their Quantitation

机译：不同血清型衣壳中重组自互补腺相关病毒基因组衣壳化的局限性及其定量
- 作者：Yuan Wang;Chen Ling;Liujiang Song;Lina Wang;George V. Aslanidi;Mengqun Tan;Changquan Ling;Arun Srivastava
- 期刊名称：《Human Gene Therapy Methods》
64.Optimization of Electroporation-Enhanced Intradermal Delivery of DNA Vaccine Using a Minimally Invasive Surface Device

机译：使用微创表面装置优化电穿孔增强DNA疫苗的皮内递送
- 作者：Feng Lin;Xuefei Shen;Gleb Kichaev;Janess M. Mendoza;Maria Yang;Philip Armendi;Jian Yan;Gary P. Kobinger;Alexander Bello;Amir S. Khan;Kate E. Broderick;Niranjan Y. Sardesai
- 期刊名称：《Human Gene Therapy Methods》
65.Inhalation of Nebulized Perfluorochemical Enhances Recombinant Adenovirus and Adeno-Associated Virus-Mediated Gene Expression in Lung Epithelium

机译：吸入雾化的全氟化物可增强肺上皮细胞中重组腺病毒和腺相关病毒介导的基因表达
- 作者：Travis Beckett;Laura Bonneau;Alan Howard;James Blanchard;Juan Borda;Daniel J. Weiner;Lili Wang;Guang Ping Gao;Jay K. Kolls;Rudolf Bohm;Denny Liggitt;Daniel J. Weiss
- 期刊名称：《Human Gene Therapy Methods》
66.A Simple and Effective Method to Generate Lentiviral Vectors for Ex Vivo Gene Delivery to Mature Human Peripheral Blood Lymphocytes

机译：一种简单有效的方法用于产生慢病毒载体用于体内基因传递给成熟的人外周血淋巴细胞
- 作者：Shicheng Yang;Neel K. Karne;Stephanie L. Goff;Mary A. Black;Hui Xu;Daniela Bischof;Kenneth Cornetta;Steven A. Rosenberg;Richard A. Morgan;Steven A. Feldman
- 期刊名称：《Human Gene Therapy Methods》
67.Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography

机译：离子交换色谱法分析重组腺伴随病毒血清型8载体的颗粒含量
- 作者：Martin Lock;Mauricio R. Alvira;James M. Wilson
- 期刊名称：《Human Gene Therapy Methods》
68.Priming of Hepatocytes Enhances In Vivo Liver Transduction with Lentiviral Vectors in Adult Mice

机译：肝细胞的启动增强了慢病毒载体在成年小鼠体内肝脏的转导。
- 作者：Virginie Pichard;Sébastien Boni;William Baron;Tuan Huy Nguyen;Nicolas Ferry
- 期刊名称：《Human Gene Therapy Methods》
69.Systemic Errors in Quantitative Polymerase Chain Reaction Titration of Self-Complementary Adeno-Associated Viral Vectors and Improved Alternative Methods

机译：自互补腺相关病毒载体定量聚合酶链反应滴定中的系统错误和改进的替代方法
- 作者：Paolo Fagone;J. Fraser Wright;Amit C. Nathwani;Arthur W. Nienhuis;Andrew M. Davidoff;John T. Gray
- 期刊名称：《Human Gene Therapy Methods》
70.Two-Dimensional Droplet Digital PCR as a Tool for Titration and Integrity Evaluation of Recombinant Adeno-Associated Viral Vectors

机译：二维液滴数字PCR作为重组腺相关病毒载体的滴定和完整性评估的工具
- 作者：Birei Furuta-Hanawa;Teruhide Yamaguchi;Eriko Uchida
- 期刊名称：《Human Gene Therapy Methods》
- droplet digital PCR qPCR two dimensional ddPCR AAV vector integrity;
71.Delineating the Cellular Mechanisms Associated with Skin Electroporation

机译：描绘与皮肤电穿孔相关的细胞机制
- 作者：Katherine Schultheis;Trevor R.F. Smith;William B. Kiosses;Kimberly A. Kraynyak;Amelia Wong;Janet Oh;Kate E. Broderick
- 期刊名称：《Human Gene Therapy Methods》
72.Efficiency and Specificity of Targeted Integration Mediated by the Adeno-Associated Virus Serotype 2 Rep 78 Protein

机译：腺相关病毒血清型2 Rep 78蛋白介导的靶向整合的效率和特异性。
- 作者：Pingjuan Li;Michael P. Marino;Jizhong Zou;Takele Argaw;Michael T. Morreale;Brian J. Iaffaldano;Jakob Reiser
- 期刊名称：《Human Gene Therapy Methods》
73.Improving the Transduction of Bone Marrow–Derived Cells with an Integrase-Defective Lentiviral Vector

机译：整合酶缺陷型慢病毒载体改善骨髓来源细胞的转导
- 作者：S. Louise Pay;Xiaoping Qi;Jeffrey F. Willard;Juliana Godoy;Kavya Sankhavaram;Ranier Horton;Sayak K. Mitter;Judith L. Quigley;Lung-Ji Chang;Maria B. Grant;Michael E. Boulton
- 期刊名称：《Human Gene Therapy Methods》
74.Impact of Inverted Terminal Repeat Integrity on rAAV8 Production Using the Baculovirus/Sf9 Cells System

机译：使用杆状病毒/ Sf9细胞系统反向末端重复完整性对rAAV8产生的影响
- 作者：Adrien Savy;Yohann Dickx;Lucile Nauwynck;Delphine Bonnin;Otto-Wilhelm Merten;Lionel Galibert
- 期刊名称：《Human Gene Therapy Methods》
75.Development of the First World Health Organization Lentiviral Vector Standard: Toward the Production Control and Standardization of Lentivirus-Based Gene Therapy Products

机译：世界卫生组织第一个慢病毒载体标准的制定：基于慢病毒的基因治疗产品的生产控制和标准化
- 作者：Yuan Zhao;Hannah Stepto;Christian K Schneider
- 期刊名称：《Human Gene Therapy Methods》
76.Improving miRNA Delivery by Optimizing miRNA Expression Cassettes in Diverse Virus Vectors

机译：通过优化多种病毒载体中的miRNA表达盒来改善miRNA传递
- 作者：Elena Herrera-Carrillo;Ying Poi Liu;Ben Berkhout
- 期刊名称：《Human Gene Therapy Methods》
77.A Guide to Approaching Regulatory Considerations for Lentiviral-Mediated Gene Therapies

机译：慢病毒介导的基因疗法的管理注意事项指南
- 作者：Michael White;Roger Whittaker;Carolina Gándara;Elizabeth A. Stoll
- 期刊名称：《Human Gene Therapy Methods》
78.A Scalable and Accurate Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate

机译：一种可扩展且准确的量化粗裂解物中重组腺相关病毒载体基因组的方法
- 作者：Jianzhong Ai;Raed Ibraheim;Phillip W.L. Tai;Guangping Gao
- 期刊名称：《Human Gene Therapy Methods》
79.RNA Trans-Splicing Targeting Endogenous β-Globin Pre-Messenger RNA in Human Erythroid Cells

机译：在人类类红细胞中靶向内源性β-球蛋白信使RNA的RNA反式剪接
- 作者：Naoya Uchida;Kareem N. Washington;Brian Mozer;Charlotte Platner;Josiah Ballantine;Luke P. Skala;Lydia Raines;Anna Shvygin;Matthew M. Hsieh;Lloyd G. Mitchell;John F. Tisdale
- 期刊名称：《Human Gene Therapy Methods》
80.OneBac 2.0: Sf9 Cell Lines for Production of AAV1 AAV2 and AAV8 Vectors with Minimal Encapsidation of Foreign DNA

机译：OneBac 2.0：Sf9细胞系用于生产AAV1AAV2和AAV8载体的最小外源DNA衣壳化
- 作者：Mario Mietzsch;Henrik Hering;Eva-Maria Hammer;Mavis Agbandje-McKenna;Sergei Zolotukhin;Regine Heilbronn
- 期刊名称：《Human Gene Therapy Methods》
81.Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors

机译：衣壳优化的AAV8载体在胰腺和胰腺肿瘤中的高效基因传递和表达
- 作者：Min Chen;Kyungah Maeng;Akbar Nawab;Rony A. Francois;Julie K. Bray;Mary K. Reinhard;Sanford L. Boye;William W. Hauswirth;Frederic J. Kaye;Georgiy Aslanidi;Arun Srivastava;Maria Zajac-Kaye
- 期刊名称：《Human Gene Therapy Methods》
82.Correction to: Hum Gene Ther Methods 2016;27(5):187–196

机译：更正为：Hum Gene Ther Methods 2016; 27（5）：187–196
- 期刊名称：《Human Gene Therapy Methods》
83.Effects of Self-Complementarity Codon Optimization Transgene and Dose on Liver Transduction with AAV8

机译：自我互补密码子优化转基因和剂量对AAV8肝转导的影响
- 作者：Peter Bell;Lili Wang;Shu-Jen Chen;Hongwei Yu;Yanqing Zhu;Mohamad Nayal;Zhenning He;John White;Deborah Lebel-Hagan;James M. Wilson
- 期刊名称：《Human Gene Therapy Methods》
84.Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn On Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model

机译：等速计量剂量多西环素的临床前疗效和安全性概况用于在神经胶质瘤模型中从高容量腺病毒载体打开治疗性转基因表达
- 作者：Nathan VanderVeen;Nicholas Raja;Elizabeth Yi;Henry Appelman;Philip Ng;Donna Palmer;Daniel Zamler;Marta Dzaman;Pedro R. Lowenstein;Maria G. Castro
- 期刊名称：《Human Gene Therapy Methods》
85.Development of rAAV2-CFTR: History of the First rAAV Vector Product to be Used in Humans

机译：rAAV2-CFTR的开发：第一个用于人类的rAAV矢量产品的历史
- 作者：Heather S. Loring;Mai K. ElMallah;Terence R. Flotte
- 期刊名称：《Human Gene Therapy Methods》
86.Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids

机译：表达超过腺相关病毒衣壳包装能力的转基因
- 作者：Kyle Chamberlain;Jalish Mahmud Riyad;Thomas Weber
- 期刊名称：《Human Gene Therapy Methods》
87.Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates

机译：基于AAV的基因治疗的小脑髓腔输送：非人类灵长类动物的技术说明
- 作者：Lluis Samaranch;John Bringas;Philip Pivirotto;Waldy San Sebastian;John Forsayeth;Krystof Bankiewicz
- 期刊名称：《Human Gene Therapy Methods》
88.Laser Photocoagulation Induces Transduction of Retinal Pigment Epithelial Cells by Intravitreally Administered Adeno-Associated Viral Vectors

机译：激光光凝诱导玻璃体内腺相关病毒载体转导视网膜色素上皮细胞。
- 作者：Si Hyung Lee;Yoon Jin Kong;Jungmook Lyu;Heuiran Lee;Keerang Park;Tae Kwann Park
- 期刊名称：《Human Gene Therapy Methods》
89.Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P a Portable Next-Generation Dermal Electroporation Device

机译：使用便携式下一代皮肤电穿孔设备CELLECTRA-3P的皮肤转染模式和电穿孔增强质粒递送的表达动力学
- 作者：Dinah H. Amante;Trevor R.F. Smith;Janess M. Mendoza;Katherine Schultheis;Jay R. McCoy;Amir S. Khan;Niranjan Y. Sardesai;Kate E. Broderick
- 期刊名称：《Human Gene Therapy Methods》
90.Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin

机译：鲁棒的慢病毒基因传递但异种移植人类皮肤中常用的腺相关病毒血清型的转导能力有限。
- 作者：Maria Jakobsen;Anne Louise Askou;Karin Stenderup;Cecilia Rosada;Frederik Dagnæs-Hansen;Thomas G. Jensen;Thomas J. Corydon;Jacob Giehm Mikkelsen;Lars Aagaard
- 期刊名称：《Human Gene Therapy Methods》
91.Stability and Compatibility of Recombinant Adeno-Associated Virus Under Conditions Commonly Encountered in Human Gene Therapy Trials

机译：在人类基因治疗试验中普遍遇到的条件下重组腺相关病毒的稳定性和相容性
- 作者：Alisha M. Gruntman;Lin Su;Qin Su;Guangping Gao;Christian Mueller;Terence R. Flotte
- 期刊名称：《Human Gene Therapy Methods》
92.AAV-8 Is More Efficient than AAV-9 in Transducing Neonatal Dog Heart

机译：在转导新生狗心脏方面AAV-8比AAV-9更有效
- 作者：Xiufang Pan;Yongping Yue;Keqing Zhang;Chady H. Hakim;Kasun Kodippili;Thomas McDonald;Dongsheng Duan
- 期刊名称：《Human Gene Therapy Methods》
93.Standard Free Droplet Digital Polymerase Chain Reaction as a New Tool for the Quality Control of High-Capacity Adenoviral Vectors in Small-Scale Preparations

机译：标准无液滴数字聚合酶链反应作为小规模制备中高容量腺病毒载体质量控制的新工具
- 作者：Philip Boehme;Thorsten Stellberger;Manish Solanki;Wenli Zhang;Eric Schulz;Thorsten Bergmann;Jing Liu;Johannes Doerner;Armin E. Baiker;Anja Ehrhardt
- 期刊名称：《Human Gene Therapy Methods》
94.Targeted Excision of VCP R155H Mutation by Cre-LoxP Technology as a Promising Therapeutic Strategy for Valosin-Containing Protein Disease

机译：Cre-LoxP技术靶向切除VCP R155H突变是一种治疗含Valosin的蛋白质疾病的有前途的治疗策略
- 作者：Angèle Nalbandian;Katrina J. Llewellyn;Christopher Nguyen;Edward S. Monuki;Virginia E. Kimonis
- 期刊名称：《Human Gene Therapy Methods》
95.T Cell Receptor-Engineered T Cells to Treat Solid Tumors: T Cell Processing Toward Optimal T Cell Fitness

机译：T细胞受体工程化T细胞治疗实体瘤：T细胞加工向最佳T细胞适应
- 作者：Cor H.J. Lamers;Sabine van Steenbergen-Langeveld;Mandy van Brakel;Corrien M. Groot-van Ruijven;Pascal M.M.L. van Elzakker;Brigitte van Krimpen;Stefan Sleijfer;Reno Debets
- 期刊名称：《Human Gene Therapy Methods》
96.Pseudotyping Lentiviral Vectors with Lymphocytic Choriomeningitis Virus Glycoproteins for Transduction of Dendritic Cells and In Vivo Immunization

机译：伪装慢病毒载体与淋巴细胞性脑膜炎病毒病毒糖蛋白的树突状细胞的转导和体内免疫。
- 作者：Chupei Zhang;Biliang Hu;Liang Xiao;Yarong Liu;Pin Wang
- 期刊名称：《Human Gene Therapy Methods》
97.Direct Transfection of Dendritic Cells in the Epidermis After Plasmid Delivery Enhanced by Surface Electroporation

机译：通过表面电穿孔增强质粒递送后表皮中树突状细胞的直接转染
- 作者：Dinah H. Amante;Trevor R.F. Smith;Bill B. Kiosses;Niranjan Y. Sardesai;Laurent M.P.F. Humeau;Kate E. Broderick
- 期刊名称：《Human Gene Therapy Methods》
98.Quantitative Evaluation of DNA Dissociation from Liposome Carriers and DNA Escape from Endosomes During Lipid-Mediated Gene Delivery

机译：脂质介导的基因传递过程中从脂质体载体的DNA解离和从内体逃逸的DNA的定量评估。
- 作者：Salomé Magalhães;Sofia Duarte;Gabriel A. Monteiro;Fábio Fernandes
- 期刊名称：《Human Gene Therapy Methods》
99.Excision Efficiency Is Not Strongly Coupled to Transgenic Rate: Cell Type-Dependent Transposition Efficiency of Sleeping Beauty and piggyBac DNA Transposons

机译：切除效率与转基因率没有强耦合：睡美人和piggyBac DNA转座子的细胞类型依赖性转座效率
- 作者：Orsolya Kolacsek;Zsuzsa Erdei;Ágota Apáti;Sára Sándor;Zsuzsanna Izsvák;Zoltán Ivics;Balázs Sarkadi;Tamás I. Orbán
- 期刊名称：《Human Gene Therapy Methods》
100.Engraftment and Lineage Potential of Adult Hematopoietic Stem and Progenitor Cells Is Compromised Following Short-Term Culture in the Presence of an Aryl Hydrocarbon Receptor Antagonist

机译：成年造血干细胞和祖细胞的植入和沿袭潜力受到芳烃受体拮抗剂的短期培养后的损害。
- 作者：Angel Gu;Monica Torres-Coronado;Chy-Anh Tran;Hieu Vu;Elizabeth W. Epps;Janet Chung;Nancy Gonzalez;Suzette Blanchard;David L. DiGiusto
- 期刊名称：《Human Gene Therapy Methods》