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Alzheimer's Dementia : Translational Research Clinical Interventions

【机译】：阿尔茨海默氏症老年痴呆症：转化型研究临床干预

ISSN：-
出版周期：Three times a year
语言：English

起始发布年份：2015
出版者：[New York, NY] : Elsevier Inc., [2015]-
出版地：United States

NLM刊名缩写：Alzheimers Dement (N Y)

数据库引入：PubMed: v2n1, 2016-, PMC

MeSH词表主题词：Alzheimer Disease*; Dementia

备注：Complemented by (work): Alzheimer's & dementia 1552-5260 (DLC) 2004215689展开▼

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1.A multimodal approach to dementia prevention: A report from the Cambridge Institute of Public Health

机译：预防痴呆症的多模式方法：剑桥公共卫生学院的报告
- 作者：Olawale Olanrewaju;Linda Clare;Linda Barnes;Carol Brayne
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
- Aging Cognitive decline Dementia Preventive health Non-pharmacological intervention Expert review;
2.Alzheimers disease assessment scale-cognitive 11-item progression model in mild-to-moderate Alzheimers disease trials of bapineuzumab

机译：bapineuzumab轻度至中度阿尔茨海默氏病试验中的阿尔茨海默氏病评估量表认知的11个项目进展模型
- 作者：Mahesh N. Samtani;Steven X. Xu;Alberto Russu;Omoniyi J. Adedokun;Ming Lu;Kaori Ito;Brian Corrigan;Sangeeta Raje;H. Robert Brashear;Scot Styren;Chuanpu Hu
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
- ADAS-cog/11 Bapineuzumab Alzheimers disease Disease progression model;
3.Pharmocologic treatment with histone deacetylase 6 inhibitor (ACY-738) recovers Alzheimers disease phenotype in amyloid precursor protein/presenilin 1 (APP/PS1) mice

机译：用组蛋白脱乙酰基酶6抑制剂（ACY-738）进行药物治疗可恢复淀粉样蛋白前体蛋白/早老素1（APP / PS1）小鼠的阿尔茨海默氏病表型
- 作者：Tabassum Majid;Deric Griffin;Zachary Criss II;Matthew Jarpe;Robia G. Pautler
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
- HDAC6 Alzheimers disease Axonal transport Acetylated tubulin Microtubule Therapeutic Preclinical ACY-738;
4.A phase 1 study to evaluate the safety and pharmacokinetics of PQ912 a glutaminyl cyclase inhibitor in healthy subjects

机译：一项1期研究用于评估健康受试者中谷氨酰胺环化酶抑制剂PQ912的安全性和药代动力学
- 作者：Inge Lues;Frank Weber;Antje Meyer;Uli Bühring;Torsten Hoffmann;Kerstin Kühn-Wache;Susanne Manhart;Ulrich Heiser;Rolf Pokorny;Joseph Chiesa;Konrad Glund
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
- Alzheimers disease Glutaminyl cyclase QC inhibitor Amyloid-beta Pyroglutamate pE-Aβ Cerebrospinal fluid;
5.Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimers disease

机译：美金刚和加兰他敏-CR的联合治疗与加兰他敏-CR的比较仅适用于初治轻度至中度阿尔茨海默氏病的抗痴呆药物患者
- 作者：Oliver Peters;Manuel Fuentes;Lisa Katharina Joachim;Frank Jessen;Christian Luckhaus;Johannes Kornhuber;Johannes Pantel;Michael Hüll;Klaus Schmidtke;Eckart Rüther;Hans-Jürgen Möller;Alexander Kurz;Jens Wiltfang;Wolfgang Maier;Birgitt Wiese;Lutz Frölich;Isabella Heuser
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
- Memantine Galantamine-CR Combination treatment Acetylcholinesterase inhibitor Alzheimers disease Dementia;
6.Delayed-start analysis for demonstrating disease modification of solanezumab

机译：延迟启动分析用于证明索拉珠单抗的疾病改良
- 作者：Frank J. Wolters;M. Arfan Ikram
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第3期
7.Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimers disease dementia: A phase 1 clinical trial

机译：阿尔茨海默氏病痴呆患者立体定向脑部注射人脐带血间充质干细胞：1期临床试验
- 作者：Hee Jin Kim;Sang Won Seo;Jong Wook Chang;Jung Il Lee;Chi Hun Kim;Juhee Chin;Soo Jin Choi;Hunki Kwon;Hyuk Jin Yun;Jong Min Lee;Sung Tae Kim;Yearn Seong Choe;Kyung-Han Lee;Duk L. Na
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Alzheimers disease Mesenchymal stem cell Stereotactic injection Hippocampus Precuneus;
8.Marked gender differences in progression of mild cognitive impairment over 8 years

机译：轻度认知障碍进展超过8年的明显性别差异
- 作者：Katherine A. Lin;Kingshuk Roy Choudhury;Bharath G. Rathakrishnan;David M. Marks;Jeffrey R. Petrella;P. Murali Doraiswamy
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Beta-amyloid Apolipoprotein ε4 Activities of daily living Gender differences Secondary prevention;
9.Delayed-start analysis: Mild Alzheimers disease patients in solanezumab trials 3.5 years

机译：延迟开始分析：solanezumab试验中的轻度阿尔茨海默氏病患者3.5年
- 作者：Hong Liu-Seifert;Eric Siemers;Karen C. Holdridge;Scott W. Andersen;Ilya Lipkovich;Christopher Carlson;Gopalan Sethuraman;Sharon Hoog;Roza Hayduk;Rachelle Doody;Paul Aisen
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Solanezumab Delayed-start Clinical trials Alzheimers disease Anti-amyloid-β antibody;
10.A 24-week study to evaluate the effect of rilapladib on cognition and cerebrospinal fluid biomarkers of Alzheimers disease

机译：一项为期24周的研究评估利拉帕地对阿尔茨海默氏病认知和脑脊液生物标志物的影响
- 作者：Gareth Maher-Edwards;Jeni DeAth;Carly Barnett;Arseniy Lavrov;Andrew Lockhart
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Lp-PLA2 Alzheimers disease Cerebrovascular disease Cognition Rilapladib SB659032 Tau Amyloid-beta peptide Albumin quotient Neurofilament light chain Cerebrospinal fluid Biomarkers Small vessel disease;
11.Alzheimers disease progression model using disability assessment for dementia scores from bapineuzumab trials

机译：使用残疾评估对bapineuzumab试验中的痴呆症评分的阿尔茨海默氏病进展模型
- 作者：Steven X. Xu;Mahesh N. Samtani;Alberto Russu;Omoniyi J. Adedokun;Ming Lu;Kaori Ito;Brian Corrigan;Sangeeta Raje;H. Robert Brashear;Scot Styren;Chuanpu Hu
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Disability assessment for dementia Bapineuzumab Alzheimers disease Disease progression model;
12.Is late-onset Alzheimers disease really a disease of midlife?

机译：晚期阿尔茨海默氏病真的是中年疾病吗？
- 作者：Karen Ritchie;Craig W. Ritchie;Kristine Yaffe;Ingmar Skoog;Nikolaos Scarmeas
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第2期
- Dementia Risk factors Alzheimers disease Intervention;
13.Web-enabled conversational interactions as a method to improve cognitive functions: Results of a 6-week randomized controlled trial

机译：基于网络的对话交互作为改善认知功能的一种方法：6周随机对照试验的结果
- 作者：Hiroko H. Dodge;Jian Zhu;Nora C. Mattek;Molly Bowman;Oscar Ybarra;Katherine V. Wild;David A. Loewenstein;Jeffrey A. Kaye
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Social engagement Conversational interaction Internet Communication technology Oregon Center for Aging and Technology (ORCATECH) Randomized controlled clinical trial Prevention study Mild cognitive impairment;
14.Impact of the care coordination program Partners in Dementia Care on veterans hospital admissions and emergency department visits

机译：护理协调计划老年痴呆症护理合作伙伴对退伍军人住院和急诊就诊的影响
- 作者：David M. Bass;Katherine S. Judge;Katie Maslow;Nancy L. Wilson;Robert O. Morgan;Catherine A. McCarthy;Wendy J. Looman;A. Lynn Snow;Mark E. Kunik
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Care-coordination Support for veterans and caregivers Hospital and ED use Partnering VA medical centers and community agencies Veteran outcomes Telephone and computer support;
15.Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimers disease

机译：SB742457在轻度至中度阿尔茨海默氏病中的两项随机对照试验
- 作者：Gareth Maher-Edwards;Carolyn Watson;John Ascher;Carly Barnett;Diane Boswell;John Davies;Manuel Fernandez;Alexander Kurz;Orazio Zanetti;Beth Safirstein;Juan Paul Schronen;Marina Zvartau-Hind;Michael Gold
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- 5-HT6 antagonist Alzheimers disease ADAS-Cog CIBIC+ CDR-SB Donepezil;
16.Neural and behavioral substrates of disorientation in mild cognitive impairment and Alzheimers disease

机译：在轻度认知障碍和阿尔茨海默氏病中迷失方向的神经和行为底物
- 作者：Amber Sousa;Jesus J. Gomar;Terry E. Goldberg
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Mild cognitive impairment Alzheimers disease Memory Structural magnetic resonance imaging FDG-PET;
17.Using baseline cognitive severity for enriching Alzheimers disease clinical trials: How does Mini-Mental State Examination predict rate of change?

机译：利用基线认知严重程度来丰富阿尔茨海默氏病的临床试验：迷你精神状态检查如何预测变化率？
- 作者：Richard E. Kennedy;Gary R. Cutter;Guoqiao Wang;Lon S. Schneider
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Alzheimer disease Clinical trials and methods Alzheimers Disease Assessment Scale Mini-Mental State Examination Clinical trials Alzheimers Disease Neuroimaging Initiative (ADNI) Alzheimers Disease Cooperative study (ADCS) Simulations;
18.The design and progress of a multidomain lifestyle intervention to improve brain health in middle-aged persons to reduce later Alzheimers disease risk: The Gray Matters randomized trial

机译：灰色领域随机试验旨在改善中年人脑部健康以降低后来的阿尔茨海默氏病风险的多领域生活方式干预措施的设计和进展：
- 作者：Maria C. Norton;Christine J. Clark;JoAnn T. Tschanz;Phillip Hartin;Elizabeth B. Fauth;Julie A. Gast;Travis E. Dorsch;Heidi Wengreen;Chris Nugent;W. David Robinson;Michael Lefevre;Sally McClean;Ian Cleland;Sydney Y. Schaefer;Sheryl Aguilar
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Lifestyle behavioral intervention Randomized controlled trial Middle age Multidomain Technology;
19.Effect of sample size re-estimation in adaptive clinical trials for Alzheimers disease and mild cognitive impairment

机译：样本量重新估计在阿尔茨海默氏病和轻度认知障碍适应性临床试验中的作用
- 作者：Guoqiao Wang;Richard E. Kennedy;Gary R. Cutter;Lon S. Schneider
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Alzheimers disease Alzheimers Disease Assessment Scale Mild cognitive impairment Sample size re-estimation Adaptive design;
20.Body brain life: A randomized controlled trial of an online dementia risk reduction intervention in middle-aged adults at risk of Alzheimers disease

机译：身体脑部生活：在线老年痴呆症风险降低干预中老年成年人患阿尔茨海默氏病的随机对照试验
- 作者：Kaarin J. Anstey;Alex Bahar-Fuchs;Pushpani Herath;Sarang Kim;Richard Burns;George W. Rebok;Nicolas Cherbuin
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Intervention Dementia prevention Risk reduction Behavior change Cognitive activity Social engagement Risk factor;
21.A phase 2 randomized controlled trial of the α7 agonist ABT-126 in mild-to-moderate Alzheimers dementia

机译：α7激动剂ABT-126在轻度至中度阿尔茨海默氏痴呆症的2期随机对照试验中
- 作者：Laura M. Gault;Craig W. Ritchie;Weining Z. Robieson;Yili Pritchett;Ahmed A. Othman;Robert A. Lenz
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
- Clinical trials randomized controlled (CONSORT agreement) Alzheimers disease Assessment of cognitive disorders/dementia Alzheimers dementia/drug therapy ABT-126;
22.Introducing Alzheimers Dementia: Translational Research Clinical Interventions an open access journal of the Alzheimers Association

机译：阿尔茨海默氏症和痴呆症简介：转化研究与临床干预阿尔茨海默氏症协会的开放期刊
- 作者：Lon S. Schneider
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2015年第1期
23.Communication Bridge: A pilot feasibility study of Internet-based speech–language therapy for individuals with progressive aphasia

机译：沟通桥梁：进行性失语症患者基于互联网的言语治疗的可行性试验研究
- 作者：Emily J. Rogalski;Marie Saxon;Hannah McKenna;Christina Wieneke;Alfred Rademaker;Marya E. Corden;Kathryn Borio;M.-Marsel Mesulam;Becky Khayum
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Primary progressive aphasia Frontotemporal dementia Alzheimers disease Speech–language pathology Apraxia of speech;
24.Alzheimers drug-development pipeline: 2016

机译：阿尔茨海默氏症的药物开发流程：2016年
- 作者：Jeffrey Cummings;Travis Morstorf;Garam Lee
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Alzheimers disease Drug development Phase I Phase II Phase III Biomarkers Amyloid Tau Cognitive enhancement;
25.Design of the NL-ENIGMA study: Exploring the effect of Souvenaid on cerebral glucose metabolism in early Alzheimers disease

机译：NL-ENIGMA研究的设计：探索类风湿关节炎对早期阿尔茨海默氏病脑葡萄糖代谢的影响
- 作者：Nienke M.E. Scheltens;Ingrid S. Kuyper;Ronald Boellaard;Frederik Barkhof;Charlotte E. Teunissen;Laus M. Broersen;Marieke M. Lansbergen;Wiesje M. van der Flier;Bart N.M. van Berckel;Philip Scheltens
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Alzheimers disease Nutritional intervention Diet Randomized clinical trial Synapse formation Synaptic activity sup18/supFFDG-PET;
26.Mnemonic strategy training of the elderly at risk for dementia enhances integration of information processing via cross-frequency coupling

机译：对有痴呆症风险的老年人的记忆策略培训通过交叉频率耦合增强了信息处理的整合
- 作者：Stavros I. Dimitriadis;Ioannis Tarnanas;Mark Wiederhold;Brenda Wiederhold;Magda Tsolaki;Elgar Fleisch
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Older adults Cognitive training Cognitive function Physical activity Augmented reality Brain plasticity Intrinsic coupling modes;
27.A multicenter randomized placebo-controlled trial for cilostazol in patients with mild cognitive impairment: The COMCID study protocol

机译：轻度认知障碍患者西洛他唑的多中心随机安慰剂对照试验：COMCID研究方案
- 作者：Satoshi Saito;Shinsuke Kojima;Naoya Oishi;Ryosuke Kakuta;Takakuni Maki;Fumihiko Yasuno;Kazuyuki Nagatsuka;Haruko Yamamoto;Hidenao Fukuyama;Masanori Fukushima;Masafumi Ihara
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Alzheimers disease Cilostazol Clearance Clinical trial Drug repositioning;
28.Measuring informed consent capacity in an Alzheimers disease clinical trial

机译：在阿尔茨海默氏病临床试验中测量知情同意能力
- 作者：Peter D. Guarino;Julia E. Vertrees;Sanjay Asthana;Mary Sano;Maria D. Llorente;Muralidhar Pallaki;Susan Love;Gerard D. Schellenberg;Maurice W. Dysken
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Informed consent Alzheimers disease Consent forms Comprehension Mental competency Third-Party consent Clinical trials as topic;
29.SAR110894 a potent histamine H3-receptor antagonist displays disease-modifying activity in a transgenic mouse model of tauopathy

机译：SAR110894是一种有效的组胺H3受体拮抗剂在tauopathy的转基因小鼠模型中显示出改善疾病的活性
- 作者：Philippe Delay-Goyet;Véronique Blanchard;Nathalie Schussler;Mati Lopez-Grancha;Jean Ménager;Véronique Mary;Eric Sultan;Armelle Buzy;Jean-Claude Guillemot;Jeanne Stemmelin;Philippe Bertrand;Thomas Rooney;Laurent Pradier;Pascal Barnéoud
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Alzheimers disease Tau pathology Cognition Histamine H3-receptor THY-Tau22 Transgenic;
30.Multiple neuropathologies and dementia in the aging brain: A key role for cerebrovascular disease?

机译：大脑老化中的多种神经病理学和痴呆：脑血管疾病的关键作用？
- 作者：Andreas Charidimou;Anand Viswanathan
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第4期
- Dementia Alzheimers disease Cerebral small vessel disease Stroke Aging;
31.NPT088 reduces both amyloid-β and tau pathologies in transgenic mice

机译：NPT088减少了转基因小鼠的淀粉样蛋白β和tau病理
- 作者：Jonathan M. Levenson;Sally Schroeter;Jenna C. Carroll;Valerie Cullen;Eva Asp;Ming Proschitsky;Charlotte H.-Y. Chung;Sharon Gilead;Muhammad Nadeem;Hemraj B. Dodiya;Shadiyat Shoaga;Elliott J. Mufson;Haim Tsubery;Rajaraman Krishnan;Jason Wright;Beka Solomon;Richard Fisher;Kimberley S. Gannon
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- GAIM General amyloid interaction motif Novel object recognition Spontaneous alternation Limb clasping Thioflavin S Brain weight Cerebrospinal fluid Phospho-tau;
32.Poor cerebrovascular function is an early marker of cognitive decline in healthy postmenopausal women

机译：脑血管功能不良是健康的绝经后妇女认知能力下降的早期标志
- 作者：Rachel H.X. Wong;Hamish M. Evans;Peter R.C. Howe
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Menopause Cerebrovascular function Pulsatility index Depression Mood Cognition;
33.First-in-human double-blind placebo-controlled single-dose escalation study of aducanumab (BIIB037) in mild-to-moderate Alzheimers disease

机译：阿达那单抗（BIIB037）在轻度至中度阿尔茨海默氏病中的首次人类双盲安慰剂对照单剂量递增研究
- 作者：James Ferrero;Leslie Williams;Heather Stella;Kate Leitermann;Alvydas Mikulskis;John OGorman;Jeff Sevigny
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Alzheimers disease Monoclonal antibody Clinical trial Pharmacokinetics Adverse events;
34.Proof of concept demonstration of optimal composite MRI endpoints for clinical trials

机译：用于临床试验的最佳复合MRI终点的概念验证
- 作者：Steven D. Edland;M. Colin Ard;Jaiashre Sridhar;Derin Cobia;Adam Martersteck;M.-Marsel Mesulam;Emily J. Rogalski
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Primary progressive aphasia PPA Clinical trial Sample size Power calculations Composite endpoint Alzheimers disease Structural magnetic resonance imaging MRI Region of interest;
35.Quantile regression to characterize solanezumab effects in Alzheimers disease trials

机译：在阿尔茨海默氏病试验中表征Solanezumab效应的分位数回归
- 作者：Yun-Fei Chen;Xiwen Ma;Karen Sundell;Karla Alaka;Kory Schuh;Joel Raskin;Robert A. Dean
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Alzheimers disease Progression Amyloid Solanezumab Quantile regression;
36.Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911 a potent oral BACE inhibitor

机译：用有效的口服BACE抑制剂JNJ-54861911治疗后分析CSF和血浆Aβ降低的动力学
- 作者：Maarten Timmers;Bianca Van Broeck;Steven Ramael;John Slemmon;Katja De Waepenaert;Alberto Russu;Jennifer Bogert;Hans Stieltjes;Leslie M. Shaw;Sebastiaan Engelborghs;Dieder Moechars;Marc Mercken;Enchi Liu;Vikash Sinha;John Kemp;Luc Van Nueten;Luc Tritsmans;Johannes Rolf Streffer
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- JNJ-54861911 Alzheimers disease Amyloid β β-secretase enzyme BACE1 BACE inhibitors;
37.B-vitamins are potentially a cost-effective population health strategy to tackle dementia: Too good to be true?

机译：B族维生素可能是解决痴呆症的一种具有成本效益的人群健康策略：太好了吗？
- 作者：Apostolos Tsiachristas;A. David Smith
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- B-Vitamins Homocysteine Cost-effectiveness Dementia UK;
38.Insufficient evidence for vitamin E in Alzheimers disease

机译：阿尔茨海默氏病中维生素E的证据不足
- 作者：Dirk M. Hermann
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Alpha-tocopherol Cognition Dementia Free radical scavenger;
39.Vitamin E family: Role in the pathogenesis and treatment of Alzheimers disease

机译：维生素E家族：在阿尔茨海默氏病的发病机理和治疗中的作用
- 作者：Virginia Boccardi;Marta Baroni;Francesca Mangialasche;Patrizia Mecocci
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第3期
- Vitamin E Alzheimers disease Mild cognitive impairment Aging Cognition Supplementation Treatment Antioxidant;
40.Dissociation of Down syndrome and Alzheimers disease effects with imaging

机译：唐氏综合症和阿尔茨海默氏病与影像的分离
- 作者：Dawn C. Matthews;Ana S. Lukic;Randolph D. Andrews;Boris Marendic;James Brewer;Robert A. Rissman;Lisa Mosconi;Stephen C. Strother;Miles N. Wernick;William C. Mobley;Seth Ness;Mark E. Schmidt;Michael S. Rafii
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Down syndrome Alzheimers Imaging Amyloid AV-45 Glucose metabolism FDG PET MRI Clinical trials Prodromal Biomarker initiative DSBI Classifier NPAIRS;
41.The ALFA project: A research platform to identify early pathophysiological features of Alzheimers disease

机译：ALFA项目：确定阿尔茨海默氏病早期病理生理特征的研究平台
- 作者：José Luis Molinuevo;Nina Gramunt;Juan Domingo Gispert;Karine Fauria;Manel Esteller;Carolina Minguillon;Gonzalo Sánchez-Benavides;Gema Huesa;Sebastián Morán;Rafael Dal-Ré;Jordi Camí
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Alzheimers disease Dementia Cohort studies Cognition Prevention Biomarkers Risk factors;
42.Assessing reliability of short and tick box forms of the ANU-ADRI: Convenient alternatives of a self-report Alzheimers disease risk assessment

机译：评估ANU-ADRI短框和滴答框形式的可靠性：自我报告阿尔茨海默氏病风险评估的便捷替代方案
- 作者：Sarang Kim;Nicolas Cherbuin;Kaarin J. Anstey
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Risk assessment Alzheimers disease Short versions Screening;
43.A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects

机译：评估健康受试者中贝沙罗汀对β-淀粉样蛋白和载脂蛋白E代谢影响的随机对照研究
- 作者：Kaushik Ghosal;Michael Haag;Philip B. Verghese;Tim West;Tim Veenstra;Joel B. Braunstein;Randall J. Bateman;David M. Holtzman;Gary E. Landreth
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Alzheimers disease Apolipoprotein E β amyloid Retinoid X receptor Bexarotene;
44.Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimers disease

机译：氟哌啶醇可灭活AMPK并降低阿尔茨海默氏病tau小鼠模型中tau的磷酸化
- 作者：Jeremy Koppel;Heidy Jimenez;Leslie Adrien;Blaine S. Greenwald;Philippe Marambaud;Ezra Cinamon;Peter Davies
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Alzheimers disease Antipsychotics AMPK Dopamine Haloperidol Tau;
45.Demonstration of safety of intravenous immunoglobulin in geriatric patients in a long-term placebo-controlled study of Alzheimers disease

机译：在阿尔茨海默氏病的长期安慰剂对照研究中证明了老年患者静脉注射免疫球蛋白的安全性
- 作者：David Gelmont;Ronald G. Thomas;Jonathan Britt;Jacqueline A. Dyck-Jones;Jennifer Doralt;Sandor Fritsch;James B. Brewer;Robert A. Rissman;Paul Aisen
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- IGIV Intravenous immunoglobulin Adverse events Alzheimers disease Safety of IGIV;
46.The roles of inflammation and immune mechanisms in Alzheimers disease

机译：炎症和免疫机制在阿尔茨海默氏病中的作用
- 作者：Linda J. Van Eldik;Maria C. Carrillo;Patricia E. Cole;Dominik Feuerbach;Barry D. Greenberg;James A. Hendrix;Matthew Kennedy;Nick Kozauer;Richard A. Margolin;José L. Molinuevo;Reinhold Mueller;Richard M. Ransohoff;Donna M. Wilcock;Lisa Bain;Kelly Bales
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第2期
- Microglia Astrocyte Innate immunity Neuroinflammation Alzheimers disease Adaptive immunity;
47.Design of a Bayesian adaptive phase 2 proof-of-concept trial for BAN2401 a putative disease-modifying monoclonal antibody for the treatment of Alzheimers disease

机译：贝叶斯适应性2期概念验证试验的设计用于BAN2401这是一种用于治疗阿尔茨海默氏病的公认的疾病改良单克隆抗体
- 作者：Andrew Satlin;Jinping Wang;Veronika Logovinsky;Scott Berry;Chad Swanson;Shobha Dhadda;Donald A. Berry
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Bayesian analysis Adaptive trial Alzheimers disease Interim analysis Monoclonal antibody Clinical trial simulation;
48.First in human study with a prodrug of galantamine: Improved benefit-risk ratio?

机译：在人类研究中首次使用加兰他敏前药：受益风险比提高了吗？
- 作者：Anne C. Baakman;Ellen t Hart;Denis G. Kay;Jasper Stevens;Erica S. Klaassen;Alfred Maelicke;Geert J. Groeneveld
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Pharmacology Galantamine Donepezil Side effects Alzheimers disease;
49.A survey of knowledge and views concerning genetic and amyloid positron emission tomography status disclosure

机译：关于遗传和淀粉样正电子发射断层扫描状态公开的知识和观点的调查
- 作者：Brian R. Ott;Marissa A. Pelosi;Geoffrey Tremont;Peter J. Snyder
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Alzheimer Prevention Amyloid PET Apolipoprotein E Survey Clinical trials;
50.A genetics-based biomarker risk algorithm for predicting risk of Alzheimers disease

机译：基于遗传学的生物标志物风险算法用于预测阿尔茨海默氏病的风险
- 作者：Michael W. Lutz;Scott S. Sundseth;Daniel K. Burns;Ann M. Saunders;Kathleen M. Hayden;James R. Burke;Kathleen A. Welsh-Bohmer;Allen D. Roses
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Biomarkers Clinical trial design Genetics of Alzheimers disease Comparison of biomarkers Assessment of risk for Alzheimers disease;
51.Suicidal ideation and behavior assessment in dementia studies: An Internet survey

机译：痴呆研究中的自杀意念和行为评估：一项互联网调查
- 作者：Phillip Chappell;Sarah Dubrava;Michelle Stewart;Dean M. Hartley;Larry Alphs;H. Robert Brashear;Yeates Conwell;David Miller;Rachel J. Schindler;Eric R. Siemers;Kristine Yaffe
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Prospective assessment of suicidal ideation and behavior in dementia Suicidal ideation and behavior in dementia clinical trials C-SSRS in dementia trials;
52.How can we really improve screening methods for AD prevention trials?

机译：我们如何才能真正改善AD预防试验的筛查方法？
- 作者：John C.S. Breitner
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
53.Considerations for the assessment of suicidal ideation and behavior in older adults with cognitive decline and dementia

机译：评估认知能力下降和痴呆老年人的自杀意念和行为的注意事项
- 作者：Larry Alphs;H. Robert Brashear;Phillip Chappell;Yeates Conwell;Sarah Dubrava;Ni A. Khin;Nicholas Kozauer;Dean M. Hartley;David S. Miller;Rachel J. Schindler;Eric R. Siemers;Michelle Stewart;Kristine Yaffe
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2016年第1期
- Suicide Suicide assessment Dementia Suicidality Elderly Suicidal ideation Suicidal behavior Suicide risk Cognitive impairment;
54.Measuring brain synaptic vesicle protein 2A with positron emission tomography and 18FUCB-H

机译：正电子发射断层扫描和18F UCB-H测量脑突触小泡蛋白2A
- 作者：Mohamed Ali Bahri;Alain Plenevaux;Joël Aerts;Christine Bastin;Guillaume Becker;Joël Mercier;Anne Valade;Tim Buchanan;Nathalie Mestdagh;Didier Ledoux;Alain Seret;André Luxen;Eric Salmon
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- SV2A Neuroimaging Synapse density Fluorine-18 PET Alzheimers disease;
55.An 8-week open-label dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations

机译：尼莫地平为期8周的开放性剂量寻找研究用于治疗GRN基因突变引起的前颗粒蛋白不足
- 作者：Sharon J. Sha;Zachary A. Miller;Sang-won Min;Yungui Zhou;Jesse Brown;Laura L. Mitic;Anna Karydas;Mary Koestler;Richard Tsai;Chiara Corbetta-Rastelli;Sophie Lin;Emma Hare;Scott Fields;Kirsten E. Fleischmann;Ryan Powers;Ryan Fitch;Lauren Herl Martens;Mehrdad Shamloo;Anne M. Fagan;Robert V. Farese Jr.;Rodney Pearlman;William Seeley;Bruce L. Miller;Li Gan;Adam L. Boxer
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Frontotemporal dementia Progranulin Genetics Nimodipine Dementia;
56.Potential implications of practice effects in Alzheimers disease prevention trials

机译：实践影响在阿尔茨海默氏病预防试验中的潜在影响
- 作者：Diane M. Jacobs;M. Colin Ard;David P. Salmon;Douglas R. Galasko;Mark W. Bondi;Steven D. Edland
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers disease Practice effects Clinical trial Single-blind run-in design Prevention Preclinical;
57.Proton pump inhibitors and the risk of severe cognitive impairment: The role of posttraumatic stress disorder

机译：质子泵抑制剂与严重认知障碍的风险：创伤后应激障碍的作用
- 作者：Sean A.P. Clouston;Oren Shapira;Roman Kotov;Lan Lei;Monika Waszczuk;Evelyn J. Bromet;Benjamin J. Luft
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Cognitive impairment Proton pump inhibitors Posttraumatic stress disorder;
58.Gamma rhythm low field magnetic stimulation alleviates neuropathologic changes and rescues memory and cognitive impairments in a mouse model of Alzheimers disease

机译：伽玛节律低场磁刺激减轻了阿尔茨海默氏病小鼠模型的神经病理变化并挽救了记忆和认知障碍
- 作者：Junli Zhen;Yanjing Qian;Xiechuan Weng;Wenting Su;Jianliang Zhang;Lihui Cai;Lin Dong;Haiting An;Ruijun Su;Jiang Wang;Yan Zheng;Xiaomin Wang
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers disease Deep-brain reachable low field magnetic stimulation Treatment Aβ Gamma oscillations Animal model;
59.The effect of diagnostic criteria on outcome measures in preclinical and prodromal Alzheimers disease: Implications for trial design

机译：诊断标准对临床前和前驱性阿尔茨海默氏病结局指标的影响：试验设计的意义
- 作者：Daniela Bertens;Betty M. Tijms;Lisa Vermunt;Niels D. Prins;Philip Scheltens;Pieter Jelle Visser
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers disease Longitudinal Biomarkers Cognitive markers Preclinical Prodromal Sample size estimates Clinical trial;
60.Characterization of APOE and TOMM40 allele frequencies in the Japanese population

机译：日本人口中APOE和TOMM40等位基因频率的表征
- 作者：Akira Nishimura;Hidenori Nonomura;Shingo Tanaka;Michihiro Yoshida;Yuka Maruyama;Yutaka Aritomi;Ann M. Saunders;Daniel K. Burns;Michael W. Lutz;Grant Runyan;Eric Lai;Kumar Budur;Allen D. Roses
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Allele frequency Alzheimers disease Apolipoprotein E (APOE) Japanese Poly-thymine (poly-T) variants Translocase of outer mitochondrial membrane 40 (TOMM40);
61.Biomathematical screening of amyloid radiotracers with clinical usefulness index

机译：具有临床实用性指标的淀粉样放射性示踪剂的生物数学筛选
- 作者：Ying-Hwey Nai;Miho Shidahara;Chie Seki;Hiroshi Watabe
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers disease Amyloid Biomathematical model Clinical usefulness Positron emission tomography (PET);
62.Impact of programs to reduce antipsychotic and anticholinergic use in nursing homes

机译：减少疗养院中抗精神病药和抗胆碱药使用计划的影响
- 作者：Ryan M. Carnahan;Grant D. Brown;Elena M. Letuchy;Linda M. Rubenstein;Brian M. Gryzlak;Marianne Smith;Jeffrey C. Reist;Michael W. Kelly;Susan K. Schultz;Michelle T. Weckmann;Elizabeth A. Chrischilles
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Antipsychotics Anticholinergics Dementia Nursing home Education;
63.Study protocol of the Intense Physical Activity and Cognition study: The effect of high-intensity exercise training on cognitive function in older adults

机译：激烈的体育活动和认知研究的研究方案：高强度运动训练对老年人认知功能的影响
- 作者：Belinda M. Brown;Stephanie R. Rainey-Smith;Natalie Castalanelli;Nicole Gordon;Shaun Markovic;Hamid R. Sohrabi;Michael Weinborn;Simon M. Laws;James Doecke;Kaikai Shen;Ralph N. Martins;Jeremiah J. Peiffer
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Exercise Cognition Dementia Study design Intervention;
64.Guide to enable health charities to increase recruitment to clinical trials on dementia

机译：指导健康慈善机构增加对痴呆症临床试验的招募
- 作者：Larry W. Chambers;Megan Harris;Elizabeth Lusk;Debbie Benczkowski
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Dementia Volunteers Recruitment Clinical trials Research participation;
65.Traumatic exposures posttraumatic stress disorder and cognitive functioning in World Trade Center responders

机译：世贸中心应对人员的创伤暴露创伤后应激障碍和认知功能
- 作者：Sean Clouston;Robert H. Pietrzak;Roman Kotov;Marcus Richards;Avron Spiro III;Stacey Scott;Yael Deri;Soumyadeep Mukherjee;Candace Stewart;Evelyn Bromet;Benjamin J. Luft
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- World Trade Center Cognitive dysfunction Trauma Particulate exposure Posttraumatic stress disorder;
66.Speed of processing training results in lower risk of dementia

机译：加快培训速度可降低痴呆症的风险
- 作者：Jerri D. Edwards;Huiping Xu;Daniel O. Clark;Lin T. Guey;Lesley A. Ross;Frederick W. Unverzagt
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Cognitive training Cognitive intervention Dementia Nonpharmacological intervention Useful field of view training;
67.Protective effect of antirheumatic drugs on dementia in rheumatoid arthritis patients

机译：抗风湿药对类风湿关节炎患者痴呆的保护作用
- 作者：Andy Judge;Cesar Garriga;Nigel K. Arden;Simon Lovestone;Dani Prieto-Alhambra;Cyrus Cooper;Christopher J. Edwards
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Dementia Rheumatoid arthritis Epidemiology Disease-modifying antirheumatic drugs (DMARDs) Methotrexate Propensity score matching Fine and gray models Clinical Practice Research Datalink Alzheimers disease;
68.A randomized exploratory molecular imaging study targeting amyloid β with a novel 8-OH quinoline in Alzheimers disease: The PBT2-204 IMAGINE study

机译：一项针对淀粉样蛋白β与新型8-OH喹啉针对阿尔茨海默氏病的随机探索性分子成像研究：PBT2-204 IMAGINE研究
- 作者：Victor L. Villemagne;Christopher C. Rowe;Kevin J. Barnham;Robert Cherny;Michael Woodward;Svetlana Bozinosvski;Olivier Salvado;Pierrick Bourgeat;Keyla Perez;Christopher Fowler;Alan Rembach;Paul Maruff;Craig Ritchie;Rudy Tanzi;Colin L. Masters
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Randomised control trial Alzheimers disease Aβ-amyloid PET molecular imaging Novel 8-OH quinoline Clinical trial design Biomarkers for Alzheimers disease;
69.Computerized cognitive training for older diabetic adults at risk of dementia: Study protocol for a randomized controlled trial

机译：对有痴呆风险的老年糖尿病成年人的计算机认知训练：一项随机对照试验的研究方案
- 作者：Rachel Bloom;Michal Schnaider-Beeri;Ramit Ravona-Springer;Anthony Heymann;Hai Dabush;Lior Bar;Shirel Slater;Yuri Rassovsky;Alex Bahar-Fuchs
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Diabetes mellitus Dementia Mild cognitive impairment Computerized cognitive training Brain training Self-management;
70.Integrating sex and gender into neurodegeneration research: A six-component strategy

机译：将性别与性别整合到神经退行性疾病研究中：六部分策略
- 作者：Mary C. Tierney;Ashley F. Curtis;Howard Chertkow;R. Jane Rylett
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Sex Gender Sex differences Sex and gender guidelines Dementia Neurodegeneration;
71.Optimizing the preclinical Alzheimers cognitive composite with semantic processing: The PACC5

机译：通过语义处理优化临床前阿尔茨海默氏症的认知综合：PACC5
- 作者：Kathryn V. Papp;Dorene M. Rentz;Irina Orlovsky;Reisa A. Sperling;Elizabeth C. Mormino
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers disease Preclinical Neuropsychological test Semantic Verbal fluency;
72.A general neurologists perspective on the urgent need to apply resilience thinking to the prevention and treatment of Alzheimers disease

机译：普通神经科医生对迫切需要将弹性思维应用于预防和治疗阿尔茨海默氏病的观点
- 作者：Grazyna Pomorska;Judith K. Ockene
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Complex system Panarchy Resilience thinking Resilience Adaptability Transformability Allostasis Allostatic load Allostatic overload;
73.Concise informed consent to increase data and biospecimen access may accelerate innovative Alzheimers disease treatments

机译：简明的知情同意以增加数据和生物标本的获取可能会加快创新性阿尔茨海默氏病的治疗
- 作者：Ann M. Hake;Penny A. Dacks;Stephen P. Arnerić
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimer disease Biospecimen Consortia Databases Data sharing Drug development tools Informed consent Regulatory sciences;
74.Toward common mechanisms for risk factors in Alzheimers syndrome

机译：寻求阿尔茨海默氏综合症危险因素的常见机制
- 作者：Miguel Medina;Zaven S. Khachaturian;Martin Rossor;Jesús Avila;Angel Cedazo-Minguez
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
- Alzheimers Dementia Syndrome Prevention Pathogenesis Risk factors;
75.Drug discovery and development: Role of basic biological research

机译：药物研发：基础生物学研究的作用
- 作者：Richard C. Mohs;Nigel H. Greig
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
76.Tangled tau: Active pathology or footprint of disease?

机译：纠结的头：活动的病理或疾病足迹？
- 作者：James P. Higham
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第4期
77.Sedentary behavior as a risk factor for cognitive decline? A focus on the influence of glycemic control in brain health

机译：久坐的行为是否会导致认知能力下降？重点关注血糖控制对脑健康的影响
- 作者：Michael J. Wheeler;Paddy C. Dempsey;Megan S. Grace;Kathryn A. Ellis;Paul A. Gardiner;Daniel J. Green;David W. Dunstan
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Dementia Alzheimers disease Cognitive function Diabetes Glucose metabolism Exercise Physical activity Light-intensity activity Sitting Sedentary behavior Breaks in sedentary time;
78.Diagnostic dilemmas in Alzheimers disease: Room for shared decision making

机译：阿尔茨海默氏病的诊断困境：共同决策的余地
- 作者：Wiesje M. van der Flier;Marleen Kunneman;Femke H. Bouwman;Ronald C. Petersen;Ellen M.A. Smets
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Shared decision making Communication Mild cognitive impairment Alzheimer Diagnostic testing;
79.A comprehensive approach to reablement in dementia

机译：综合治疗痴呆症的方法
- 作者：Christopher J. Poulos;Antony Bayer;Lauren Beaupre;Linda Clare;Roslyn G. Poulos;Rosalie H. Wang;Sytse Zuidema;Katherine S. McGilton
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Rehabilitation Dementia Reablement Aged Exercise Pharmacologic management Hip fracture Activities of daily living Recovery of function Caregiver Cognitive impairment;
80.Clinicians views on conversations and shared decision making in diagnostic testing for Alzheimers disease: The ABIDE project

机译：临床医师对阿尔茨海默氏病诊断测试中的对话和共同决策的观点：ABIDE项目
- 作者：Marleen Kunneman;Ellen M.A. Smets;Femke H. Bouwman;Niki S.M. Schoonenboom;Marissa D. Zwan;Ruth Pel-Littel;Wiesje M. van der Flier
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Shared decision making Communication Dementia Alzheimer Diagnostic testing;
81.Patients and caregivers views on conversations and shared decision making in diagnostic testing for Alzheimers disease: The ABIDE project

机译：患者和护理人员对阿尔茨海默氏病诊断测试中的对话和共同决策的看法：ABIDE项目
- 作者：Marleen Kunneman;Ruth Pel-Littel;Femke H. Bouwman;Freek Gillissen;Niki S.M. Schoonenboom;Jules J. Claus;Wiesje M. van der Flier;Ellen M.A. Smets
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Shared decision making Communication Dementia Alzheimer Diagnostic testing;
82.The BDNF Val66Met polymorphism moderates the effect of cognitive reserve on 36-month cognitive change in healthy older adults

机译：BDNF Val66Met多态性减轻了健康老年人的认知储备对36个月认知变化的影响
- 作者：David D. Ward;Ross Andel;Nichole L. Saunders;Megan E. Thow;Shannon Z. Klekociuk;Aidan D. Bindoff;James C. Vickers
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Cognitive reserve Brain reserve Brain-derived neurotrophic factor BDNF Aging Cognitive function Cognitive change;
83.Technology for home dementia care: A prototype locating system put to the test

机译：家庭痴呆症护理技术：经过测试的原型定位系统
- 作者：Herlind Megges;Silka Dawn Freiesleben;Natalie Jankowski;Brigitte Haas;Oliver Peters
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Assistive living technologies Technology Caregivers Dementia Locating systems Tracking systems User experience Usability;
84.Multiple-dose ponezumab for mild-to-moderate Alzheimers disease: Safety and efficacy

机译：轻度至中度阿尔茨海默氏病多剂量ponezumab的安全性和有效性
- 作者：Jaren W. Landen;Sharon Cohen;Clare B. Billing Jr.;Carol Cronenberger;Scot Styren;Aaron H. Burstein;Catherine Sattler;Jae-Hong Lee;Clifford R. Jack Jr.;Kejal Kantarci;Pamela F. Schwartz;William T. Duggan;Qinying Zhao;Ken Sprenger;Martin M. Bednar;Brendon Binneman
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Amyloid β Biomarkers Cerebrospinal fluid Immunotherapy Monoclonal antibody Pharmacokinetics Pharmacodynamics Phase-II study Ponezumab;
85.The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimers disease

机译：非编码aquaporin-4单核苷酸多态性对阿尔茨海默氏病认知和功能进展的影响
- 作者：Kevin G. Burfeind;Charles F. Murchison;Shawn K. Westaway;Matthew J. Simon;Deniz Erten-Lyons;Jeffrey A. Kaye;Joseph F. Quinn;Jeffrey J. Iliff
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Genetics Glymphatic system Aquaporin-4 Amyloid β Cognitive decline Cohort study;
86.Power analysis to detect treatment effects in longitudinal clinical trials for Alzheimers disease

机译：在纵向临床试验中检测阿尔茨海默氏病治疗效果的功效分析
- 作者：Zhiyue Huang;Graciela Muniz-Terrera;Brian D.M. Tom
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Power analysis Clinical trial Sample size Multivariate linear mixed-effects model Composite score Alzheimers disease;
87.Determining the impact of psychosis on rates of false-positive and false-negative diagnosis in Alzheimers disease

机译：确定精神病对阿尔茨海默氏病假阳性和假阴性诊断率的影响
- 作者：Corinne E. Fischer;Winnie Qian;Tom A. Schweizer;Zahinoor Ismail;Eric E. Smith;Colleen P. Millikin;David G. Munoz
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Psychosis Alzheimers disease Misdiagnosis Neuropathology Delusions Hallucinations Diagnosis;
88.Ponezumab in mild-to-moderate Alzheimers disease: Randomized phase II PET-PIB study

机译：轻度至中度阿尔茨海默氏病中的Ponezumab：随机II期PET-PIB研究
- 作者：Jaren W. Landen;Niels Andreasen;Carol L. Cronenberger;Pamela F. Schwartz;Anne Börjesson-Hanson;Henrik Östlund;Catherine A. Sattler;Brendon Binneman;Martin M. Bednar
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Antibody Amyloid Pharmacokinetics Pharmacodynamics Ponezumab PIB Safety Tolerability Anti-drug antibodies;
89.Serum concentrations of vitamin E and carotenoids are altered in Alzheimers disease: A case-control study

机译：阿尔茨海默氏病患者血清维生素E和类胡萝卜素的浓度发生变化：一项病例对照研究
- 作者：Kathryn Mullan;Michael A. Williams;Chris R. Cardwell;Bernadette McGuinness;Peter Passmore;Giuliana Silvestri;Jayne V. Woodside;Gareth J. McKay
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- α-Carotene α-Tocopherol β-Carotene β-Cryptoxanthin γ-Tocopherol Lutein Lycopene Retinol Zeaxanthin;
90.Combined mnemonic strategy training and high-definition transcranial direct current stimulation for memory deficits in mild cognitive impairment

机译：联合记忆策略训练和高清经颅直流电刺激治疗轻度认知障碍患者的记忆缺陷
- 作者：Benjamin M. Hampstead;Krishnankutty Sathian;Marom Bikson;Anthony Y. Stringer
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Aging Dementia Alzheimers disease Learning Memory Cognitive rehabilitation Cognitive training Neurorehabilitation fMRI tDCS Neurostimulation Neuromodulation;
91.Midlife anticholinergic drug use risk of Alzheimers disease and brain atrophy in community-dwelling older adults

机译：在社区居住的老年人中使用中年抗胆碱能药物患阿尔茨海默氏病的风险和脑萎缩
- 作者：Yi-Fang Chuang;Palchamy Elango;Christopher E. Gonzalez;Madhav Thambisetty
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Anticholinergic medication Alzheimers disease Brain atrophy Cortical thickness Longitudinal change Brain aging Midlife;
92.Alzheimers disease drug development pipeline: 2017

机译：阿尔茨海默氏病药物开发流程：2017年
- 作者：Jeffrey Cummings;Garam Lee;Travis Mortsdorf;Aaron Ritter;Kate Zhong
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Phase I Phase II Phase III Biomarkers Preclinical AD Prodromal AD AD dementia;
93.Phase II clinical trials of anti–amyloid β antibodies: When is enough enough?

机译：抗淀粉样β抗体的II期临床试验：何时足够？
- 作者：Michael Gold
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Clinical trials Pharmacology Phase II Phase III Monoclonal antibodies Amyloid β Investment;
94.Lower brain and blood nutrient status in Alzheimers disease: Results from meta-analyses

机译：阿尔茨海默氏病中较低的大脑和血液营养状况：荟萃分析的结果
- 作者：Martijn C. de Wilde;Bruno Vellas;Elodie Girault;Aysun Cetinyurek Yavuz;John W. Sijben
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Brain Cerebrospinal fluid Plasma Nutrient Nutritional requirement Metabolism Omega-3 polyunsaturated fatty acids DHA Choline Vitamins Phosphatidylcholine Phospholipid synthesis Synapse Neuronal membrane;
95.Neuropsychiatric signs and symptoms of Alzheimers disease: New treatment paradigms

机译：阿尔茨海默氏病的神经精神症状和体征：新的治疗范例
- 作者：Krista L. Lanctôt;Joan Amatniek;Sonia Ancoli-Israel;Steven E. Arnold;Clive Ballard;Jiska Cohen-Mansfield;Zahinoor Ismail;Constantine Lyketsos;David S. Miller;Erik Musiek;Ricardo S. Osorio;Paul B. Rosenberg;Andrew Satlin;David Steffens;Pierre Tariot;Lisa J. Bain;Maria C. Carrillo;James A. Hendrix;Heidi Jurgens;Brendon Boot
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Alzheimers disease Neuropsychiatric symptoms Trial design Delusions Hallucinations Agitation Apathy Depression Sleep disturbance;
96.A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study

机译：听力治疗以减少认知能力下降的随机可行性试验性试验：老年人试点研究中的年龄和认知健康评估结果
- 作者：Jennifer A. Deal;Marilyn S. Albert;Michelle Arnold;Shrikant I. Bangdiwala;Theresa Chisolm;Sonia Davis;Ann Eddins;Nancy W. Glynn;Adele M. Goman;Melissa Minotti;Thomas Mosley;George W. Rebok;Nicholas Reed;Elizabeth Rodgers;Victoria Sanchez;A. Richey Sharrett;Josef Coresh;Frank R. Lin
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第3期
- Clinical trials Cognition Dementia Epidemiology Hearing Longitudinal study Memory Presbycusis;
97.The effect of statins on rate of cognitive decline in mild cognitive impairment

机译：他汀类药物对轻度认知障碍患者认知能力下降的影响
- 作者：Kyle B. Smith;Paul Kang;Marwan N. Sabbagh
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第2期
- Statin Alzheimers disease Mild cognitive impairment ADAS ADNI;
98.Design of the ExCersion-VCI study: The effect of aerobic exercise on cerebral perfusion in patients with vascular cognitive impairment

机译：ExCersion-VCI研究的设计：有氧运动对血管性认知障碍患者脑灌注的影响
- 作者：Anna E. Leeuwis;Astrid M. Hooghiemstra;Raquel Amier;Doeschka A. Ferro;Leonie Franken;Robin Nijveldt;Joost P.A. Kuijer;Anne-Sophie G.T. Bronzwaer;Johannes J. van Lieshout;Marc B. Rietberg;Janne M. Veerbeek;Rosalie J. Huijsmans;Frank J.G. Backx;Charlotte E. Teunissen;Esther E. Bron;Frederik Barkhof;Niels D. Prins;Rahil Shahzad;Wiro J. Niessen;Albert de Roos;Matthias J.P. van Osch;Albert C. van Rossum;Geert J. Biessels;Wiesje M. van der Flier
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第2期
- Cerebral blood flow Exercise Arterial spin labeling Randomized clinical trial Cognition Vascular cognitive impairment;
99.Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimers disease

机译：靶向丁酰胆碱酯酶用于阿尔茨海默氏病的临床前单光子发射计算机断层扫描（SPECT）成像
- 作者：Drew R. DeBay;George A. Reid;Ian R. Pottie;Earl Martin;Chris V. Bowen;Sultan Darvesh
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第2期
- Alzheimers disease Butyrylcholinesterase Acetylcholinesterase Single-photon emission computed tomography Molecular imaging Neuroimaging sup123/supIodine Alzheimer mouse model with 5 familial mutations;
100.Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimers disease in Vietnam Veterans using the Alzheimers Disease Neuroimaging Initiative: Preliminary report

机译：使用阿尔茨海默氏病神经影像学举措越南脑部创伤性创伤和创伤后应激障碍对阿尔茨海默氏病发展的影响：初步报告
- 作者：Michael W. Weiner;Danielle Harvey;Jacqueline Hayes;Susan M. Landau;Paul S. Aisen;Ronald C. Petersen;Duygu Tosun;Dallas P. Veitch;Clifford R. Jack Jr.;Charles Decarli;Andrew J. Saykin;Jordan Grafman;Thomas C. Neylan
- 期刊名称：《Alzheimer's Dementia : Translational Research Clinical Interventions》 | 2017年第2期
- Traumatic brain injury Posttraumatic stress disorder Alzheimers disease Vietnam veterans Mild cognitive impairment;