Paeonidanins F-H: Three new dimeric monoterpene glycosides from Paeonia lactiflora and their anti-inflammatory activity

摘要

Three new dimeric monoterpene glycosides, paeonidanins F-H (1-3) were isolated from the roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Compounds 1-3 showed inhibitory effects against nitric oxide (NO) and pro-inflammatory cytokine TNF-alpha release in LPS-induced RAW 246.7 macrophages. (c) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.