Oxytrofalcatins AF, N-benzoylindole analogues from the roots of Oxytropis falcata (Leguminosae)

摘要

Indole alkaloids, oxytrofalcatins AF (16), together with five other known alkaloids (711), were isolated from the roots of Oxytropis falcata. Their structures were elucidated by comprehensive spectroscopic analyses, including using 1D and 2D NMR spectroscopy and mass spectrometry. This is the first report of N-benzoylindoles from a natural source. Compounds 16 lacked significant cytotoxicity against SGC-7901 and HL-60 tumor cell lines.