Pregnanes and pregnane glycosides from Marsdenia roylei

摘要

Two pregranes namely desacylkondurangogenin C (1) and deniagenin (3, new) and two new pregnane glycosides designated as denin (5) and marsin (12) have been isolated from chloroform soluble extract of dried stem of Marsdenia rovlei. Chemical and spectroscopic evidences are consistent with the structures of deniagenin, denin and marsin as 3beta, 11alpha, 12p, 14beta, 17beta, 20-hexahydroxy pregn-5-ene,desacylkondurangogenin C-3-O-alpha-D-glucopyranosyl-(1-->4)-O-alpha-L-fucopyranoside and ketocalogenin-3-O-alpha-L-fucopyranoside, respectively.