Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats

Jurga Agnieszka M.; Piotrowska Anna; Starnowska Joanna; Rojewska Ewelina; Makuch Wioletta; Mika Joanna

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Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats

机译：一氧化碳释放分子（CORM-2）的治疗可抑制神经性疼痛并增强大鼠阿片类药物的功效

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Background: Experiments were conducted to evaluate the contribution of P2X4 receptors to the modulation of neuropathy and their ability to amplify opioid effectiveness.

机译：背景：进行了实验，以评估P2X4受体对神经病调节的贡献及其增强阿片样物质功效的能力。

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来源
《Pharmacological reports: PR》 |2016年第1期|共8页
作者
Jurga Agnieszka M.; Piotrowska Anna; Starnowska Joanna; Rojewska Ewelina; Makuch Wioletta; Mika Joanna;
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正文语种 eng
中图分类药学;
关键词
P2X4R; Chronic constriction injury; Morphine; Buprenorphine; CORM-2;

机译：P2X4R;慢性压迫性损伤;吗啡;丁丙诺啡;CORM-2;

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1. Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats [J] . Jurga Agnieszka M., Piotrowska Anna, Starnowska Joanna, Pharmacological reports: PR . 2016,第1期

机译：一氧化碳释放分子（CORM-2）的治疗可抑制神经性疼痛并增强大鼠阿片类药物的功效
2. Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of μ-opioid receptors during neuropathic pain [J] . HerveraA., LeánezS., MotterliniR., Anesthesiology . 2013,第5期

机译：一氧化碳释放分子和HO-1诱导剂的治疗增强了神经性疼痛中μ阿片受体的作用和表达
3. Treatment with a carbon monoxide-releasing molecule inhibits chronic inflammatory pain in mice: Nitric oxide contribution [J] . NegreteR., HerveraA., LeánezS., Psychopharmacology . 2014,第5期

机译：一氧化碳释放分子治疗可抑制小鼠的慢性炎症性疼痛：一氧化氮的贡献
4. Design and Synthesis of Novel Blfunctional Ligands (Opioid Agonist and Bradykinin Antagonist) for Treatment of Chronic and Neuropathic Pain [C] . Srinivas Deekonda, David Rankin, Peg Davis American Peptide Symposium . 2011

机译：设计与合成新型血官能配体（阿片类激动剂和Bradykinin拮抗剂）治疗慢性和神经性疼痛
5. The role of N-acetyl-L-cysteine (NAC) as an adjuvant to opioid treatment in patients with inadequately controlled chronic neuropathic pain. [D] . Moore, Thomas Burton. 2016

机译：N-乙酰-L-半胱氨酸（NAC）作为阿片类药物治疗辅助剂在慢性神经性疼痛控制不当的患者中的作用。
6. The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells [O] . J Megías, J Busserolles, M J Alcaraz 2007

机译：一氧化碳释放分子CORM-2抑制Caco-2细胞中细胞因子诱导的炎症反应
7. The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells [O] . Megías, J, Busserolles, J, Alcaraz, M J 2009

机译：一氧化碳释放分子CORM-2抑制Caco-2细胞中细胞因子诱导的炎症反应

Treatment with a carbon monoxide-releasing molecule (CORM-2) inhibits neuropathic pain and enhances opioid effectiveness in rats

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