A simple and efficient one-step synthesis of 2,4,10a-triaryl-1,10a-dihydro-2H-pyrazino[2,1-b][1,3] benzothiazoles catalyzed by p-toluene sulfonic acid

摘要

A series of 2,4,10a-triaryl-1,10a-dihydro-2H-pyrazino[2,1-b][1,3]benzothiazoles were prepared in good yields by the reaction of 2-[(2-oxo-2-arylethyl) anilino]-laryl-1-ethanones with 2-aminothiophenol in the presence of p-toluenesulfonic acid under solventless, conditions. The products were characterized by H-1 NMR and C-13 NMR spectroscopy.