Dipolar cycloaddition reactions with thiazolonylhydrazones: A new route for the synthesis of several new thienyl- and furyl-thiazolonylpyrrolopyrazole derivatives of expected biological activities

摘要

Several new pyrrolopyrazoles were synthesized via the reactions of each of 2-thiophenecarboxaldehyde thiazolonylhydrazone or 2-furaldehyde thiazolonylhydrazone with N-substituted maleimides followed by partial dehydogenation using bromobenzene and complete aromatization using nitrobenzene. Structures were established on the basis of elemental analyses and spectroscopic data studies. [References: 22]