Dinitrogen tetroxide impregnated charcoal (N2O4/charcoal): Selective oxidation of thiols to disulfides or thiosulfonates

摘要

Selective oxidation of thiols to disulfides (RSSR) was performed by using catalytic amounts of dinitrogen tetroxide/charcoal in chloroform at r.t. while the reaction of thiols with four molar equivalents of the reagent in dichloromethane afforded thiosulfonates (RSO2SR) with excellent yields.