Synthesis of competitive inhibitors of phospholipase A(2) (PLA(2))

摘要

The synthetic routes for preparation of several phospholipid analogues such as lithium alkyl-3-alkoxy allylvinyl-sn-glycerol 5 and 6 and lithium trans-2-amidomethyl phosphate 7 and lithium cholesterol ester phosphate 8 containing ether, amide, and phosphate ester moieties are described. [References: 18]