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Technical considerations for implementation of x-ray CT polymer gel dosimetry.

机译:实施X射线CT聚合物凝胶剂量测定的技术注意事项。

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摘要

Gel dosimetry is the most promising 3D dosimetry technique in current radiation therapy practice. X-ray CT has been shown to be a feasible method of reading out polymer gel dosimeters and, with the high accessibility of CT scanners to cancer hospitals, presents an exciting possibility for clinical implementation of gel dosimetry. In this study we report on technical considerations for implementation of x-ray CT polymer gel dosimetry. Specifically phantom design, CT imaging methods, imaging time requirements and gel dose response are investigated. Where possible, recommendations are made for optimizing parameters to enhance system performance. The dose resolution achievable with an optimized system is calculated given voxel size and imaging time constraints. Results are compared with MRI and optical CT polymer gel dosimetry results available in the literature.
机译:凝胶剂量测定是当前放射治疗实践中最有前途的3D剂量测定技术。 X射线CT已被证明是一种读取聚合物凝胶剂量计的可行方法,并且由于CT扫描仪对癌症医院的高度可达性,为临床进行凝胶剂量测定提供了令人兴奋的可能性。在这项研究中,我们报告了实施X射线CT聚合物凝胶剂量测定的技术考虑。特别是幻像设计,CT成像方法,成像时间要求和凝胶剂量响应进行了调查。如有可能,建议优化参数以增强系统性能。在给定体素大小和成像时间限制的情况下,可以使用优化的系统获得剂量分辨率。将结果与文献中提供的MRI和光学CT聚合物凝胶剂量测定结果进行比较。

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