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Development of an easy-to-handle range measurement tool using a plastic scintillator for proton beam therapy

机译:使用塑料闪烁体进行质子束治疗的易于操作的距离测量工具的开发

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Proton beam therapy can concentrate the dose on a tumour. In order to offer high-precision proton beam therapy to the patient, it is important to confirm the range every day. At the National Cancer Center Hospital East ( NCC), the range measurement tool consists of a water phantom and an ionization chamber. These large and heavy tools take a long time to set up. Therefore, we developed a simple and easy-to-handle range measurement tool for proton beam therapy. This tool consists of a plastic scintillator block and a CCD camera. We recorded visible scintillation light generated by proton irradiation on the scintillator, and could measure the range from the shape of light distribution by using a computer with automatic analysis software installed. We carried out proton irradiation experiments with this tool to examine its performance as a tool of daily range measurements. The precision of the range measurement is within 0.3 mm ( sd). The tool can measure possible short-term range variation with 1 s sampling time during the time interval of a typical treatment in a few minutes. We conclude that this tool can measure the range with sufficient resolution in a short time, and is useful for range control in a clinical setting.
机译:质子束治疗可以将剂量集中在肿瘤上。为了向患者提供高精度的质子束治疗,每天确定范围非常重要。在东部的美国国家癌症中心医院(NCC),范围测量工具由一个水模和一个电离室组成。这些大型而繁重的工具需要很长时间才能建立。因此,我们开发了用于质子束治疗的简单易用的距离测量工具。该工具由一个塑料闪烁体块和一个CCD照相机组成。我们在闪烁器上记录了质子辐照产生的可见闪烁光,并且可以通过使用装有自动分析软件的计算机来测量光分布形状的范围。我们使用此工具进行了质子辐照实验,以检查其作为日常范围测量工具的性能。范围测量的精度在0.3毫米(sd)以内。该工具可以在几分钟内一次典型治疗的时间间隔内以1 s的采样时间测量可能的短期范围变化。我们得出的结论是,该工具可以在短时间内以足够的分辨率测量范围,对于临床环境中的范围控制非常有用。

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