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In vitro uses of biological cryoprotectants

机译:生物冷冻保护剂的体外用途

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摘要

Ice can be anything from a highly destructive agent in agriculture to a useful building material. Established industries are based on the known rules of physics and chemistry which allow some control of amounts of ice or ice crystal geometry. However, organisms have much more subtle requirements to maintain their delicate internal structure if they are to survive freezing. As a result they have selected specific molecules for freezing-point depression, osmotic regulation, ice nucleation and crystal growth inhibition. All these active species may have potential commercial use once they are identified, understood and produced at economic scales. We examine the progress made so far in extending biological subtlety into commercial processes, and look for prospects for further innovation. [References: 39]
机译:冰可以是任何东西,从农业中的高破坏力剂到有用的建筑材料。已建立的行业基于已知的物理和化学规则,可以对冰或冰晶的几何形状进行一定程度的控制。但是,如果要在冰冻环境中生存,生物对维持其脆弱的内部结构的要求就更高得多。结果,他们选择了特定的分子来降低冰点,调节渗透,制冰和抑制晶体生长。一旦确定,理解并以经济规模生产它们,所有这些活性物种都可能具有潜在的商业用途。我们检查了迄今为止在将生物细微之处扩展到商业流程中所取得的进展,并寻找了进一步创新的前景。 [参考:39]

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