Sample size calculation for the one-sample log-rank test

摘要

In this paper, an exact variance of the one-sample log-rank test statistic is derived under the alternative hypothesis, and a sample size formula is proposed based on the derived exact variance. Simulation results showed that the proposed sample size formula provides adequate power to design a study to compare the survival of a single sample with that of a standard population. Copyright (c) 2014 John Wiley & Sons, Ltd.