Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions

Duarte Iris; Santos Jose Luis; Pinto Joao F.; Temtem Marcio

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Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions

机译：喷雾干燥无定形固体分散体开发的筛选方法

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摘要

To present a new screening methodology intended to be used in the early development of spray-dried amorphous solid dispersions.

机译：介绍一种旨在用于喷雾干燥无定形固体分散体早期开发的新筛选方法。

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来源
《Pharmaceutical research》 |2015年第1期|共16页
作者
Duarte Iris; Santos Jose Luis; Pinto Joao F.; Temtem Marcio;
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正文语种 eng
中图分类生药学（天然药物学）;
关键词
Amorphous solid dispersion; miscibility; screening method; solvent casting; spray drying;

机译：非晶态固体分散体;混溶性;筛选方法;溶剂流延;喷雾干燥;

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专利

1. Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions [J] . Íris Duarte, José Luís Santos, João F. Pinto, Pharmaceutical Research . 2015,第1期

机译：喷雾干燥无定形固体分散体开发的筛选方法
2. Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions [J] . Duarte Iris, Santos Jose Luis, Pinto Joao F., Pharmaceutical research . 2015,第1期

机译：用于开发喷雾干燥无定形固体分散体的筛选方法
3. Investigation into the Solid-State Properties and Dissolution Profile of Spray-Dried Ternary Amorphous Solid Dispersions: A Rational Step toward the Design and Development of a Multicomponent Amorphous System [J] . Baghel Shrawan, Cathcart Helen, OReilly Niall J. Molecular pharmaceutics . 2018,第9期

机译：喷雾干燥三元无定形实体分散体的固态特性和溶出曲线的研究：朝向多组分非晶系统的设计和开发的理性步骤
4. A practical computational tool to predict formulation and process variables during the development of spray-dried amorphous solid dispersions [C] . Iris Duarte, José Luís Santos, Jo?o F. Pinto, AIChE Meeting . 2015

机译：一种实用的计算工具，用于在喷雾干燥的无定形固体分散体的开发过程中预测配方和过程变量
5. Pharmaceutical cocrystals and amorphous spray-dried dispersions of tenoxicam: Solubility and dissolution enhancement approaches. [D] . Patel, Jagdishwar R. 2012

机译：替诺昔康的药物共晶体和无定形喷雾干燥分散体：溶解度和溶解度提高方法。
6. Prediction of Phase Behavior of Spray-Dried Amorphous Solid Dispersions: Assessment of Thermodynamic Models Standard Screening Methods and a Novel Atomization Screening Device with Regard to Prediction Accuracy [O] . Aymeric Ousset, Pierre-François Chavez, Joke Meeus, 2018

机译：喷雾干燥无定形固体分散体的相行为预测：热力学模型评估标准筛选方法和一种基于预测准确性的新型雾化筛选装置
7. Development and Characterization of Spray-dried Amorphous Solid Dispersion of Sildenafil: In vivo Evaluation [O] . Mohammed Muqtader A, Farhat Fatima, Md. Khalid Anw, 2020

机译：Sildenafil喷雾干燥无定形固体分散体的开发和表征：体内评价
8. Development of a High-Throughput Method for the Optical Screening of Phase Transformations Related to Amorphous Materials for Harsh Environment Applications. [R] . Ludwig, A. 2012

机译：用于恶劣环境应用的非晶材料相变光学筛选的高通量方法的开发。

Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions

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