Search For New Drugs Synthesis And Antileukemic Activity Of N-Phthaloyl-2-Aminoalcohols

摘要

Optically active 2-aminoalcohols have found wide use as ligands for the catalysts of asymmetric synthesis [1] and are key intermediates in the synthesis of some biologically active substances [2, 3]. Being structurally similar to native amino acids, 2-aminoalcohol residues can be used instead of the amino acid residues in the synthesis of peptide analogs and related isosteric compounds [4]. However, some simpler derivatives of 2-aminoalcohols also possess significant physiological activity.