Cumulative Organic Anion Transporter-Mediated Drug-Drug Interaction Potential of Multiple Components in Salvia Miltiorrhiza (Danshen) Preparations

Wang Li; Venitz Juergen; Sweet Douglas H.

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Cumulative Organic Anion Transporter-Mediated Drug-Drug Interaction Potential of Multiple Components in Salvia Miltiorrhiza (Danshen) Preparations

机译：丹参制剂中多种成分的累积有机阴离子转运体介导的药物-药物相互作用潜能

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摘要

To evaluate organic anion transporter-mediated drug-drug interaction (DDI) potential for individual active components of Danshen (Salvia miltiorrhiza) vs. combinations using in vitro and in silico approaches.

机译：若要评估丹参（丹参）各个活性成分与组合使用体外和计算机模拟方法的有机阴离子转运蛋白介导的药物相互作用（DDI）的潜力。

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《Pharmaceutical research》 |2014年第12期|共12页
作者
Wang Li; Venitz Juergen; Sweet Douglas H.;
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正文语种 eng
中图分类生药学（天然药物学）;
关键词
Drug elimination; OATs; Solute carriers; Traditional Chinese medicine; Transporter modeling;

机译：药物消除;OAT;溶媒;中药;运输模型;

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1. Cumulative Organic Anion Transporter-Mediated Drug-Drug Interaction Potential of Multiple Components in Salvia Miltiorrhiza (Danshen) Preparations [J] . Wang Li, Venitz Juergen, Sweet Douglas H. Pharmaceutical research . 2014,第12期

机译：丹参制剂中多种成分的累积有机阴离子转运体介导的药物-药物相互作用潜能
2. Competitive inhibition of human organic anion transporters 1 (SLC22A6), 3 (SLC22A8) and 4 (SLC22A11) by major components of the medicinal herb Salvia miltiorrhiza (Danshen) [J] . WangL., SweetD.H. Drug metabolism and pharmacokinetics. . 2013,第3期

机译：药草丹参的主要成分对人有机阴离子转运蛋白1（SLC22A6），3（SLC22A8）和4（SLC22A11）的竞争抑制作用
3. Competitive Inhibition of Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8) and 4 (SLC22A11) by Major Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) [J] . Li WANG, Douglas H. SWEET Drug metabolism and pharmacokinetics. . 2013,第3期

机译：药草丹参的主要成分对人类有机阴离子转运蛋白1（SLC22A6），3（SLC22A8）和4（SLC22A11）的竞争抑制作用
4. Preparation and characterization of organically modified silica monolithic weak anion-exchange column for CEC [C] . International Beijing conference and exhibition on instrumental analysis;BCEIA 2003 . 2003

机译：用于CEC的有机改性二氧化硅整体式弱阴离子交换柱的制备和表征
5. Assessment of the drug-drug interaction potential of anionic components in the diet and herbal medicines on organic anion transporters (SLC22 family). [D] . Wang, Li. 2013

机译：评估饮食和草药中阴离子成分在有机阴离子转运蛋白（SLC22系列）上的药物-药物相互作用潜力。
6. Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) [O] . Li Wang, Douglas H. Sweet 2012

机译：药用丹参（丹参）的活性亲水成分有效抑制有机阴离子转运蛋白1（Slc22a6）和3（Slc22a8）
7. Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) [O] . Wang Li, Sweet Douglas H. 2012

机译：药用丹参（丹参）的活性亲水成分有效抑制有机阴离子转运蛋白1（Slc22a6）和3（Slc22a8）

Cumulative Organic Anion Transporter-Mediated Drug-Drug Interaction Potential of Multiple Components in Salvia Miltiorrhiza (Danshen) Preparations

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